Navigation Links
Optimal Warfarin Dosing Improves Anticoagulation Control
Date:12/30/2008

Increasing time within the therapeutic range of utmost importance, study finds

TUESDAY, Dec. 30 (HealthDay News) -- While the anticoagulant warfarin can be highly effective in preventing strokes and treating venous thromboembolism, doctors have long struggled with finding the best way manage the drug therapy.

Boston University School of Medicine (BUSM) researchers now claim to have figured out the optimal dosing levels to help patients, according to a study published in December online issue of the Journal of Thrombosis and Haemostasis.

The research team analyzed warfarin use in almost 4,000 patients to determine what are the most effective levels of the drug in a patient's system under different circumstances.

"The study suggests that anticoagulation control could be improved considerably by changing the warfarin dose only when the ratio is 1.7 or lower/3.3 or higher," lead author Dr. Adam Rose, an assistant professor of medicine at BUSM, said in a university news release. "In addition to offering warfarin to as many optimal candidates as possible, we also need to optimize warfarin dose management to fully realize the benefits of anticoagulation."

Previous studies have found that doctors often do not prescribe warfarin enough or at less than optimal doses for patients who could most benefit from it. Part of the reason is not enough is known about proper dosing levels, and misuse of warfarin can put patients at a higher risk of stroke, bleeding and other medical complications.

"This lack of evidence regarding optimal management strategies probably contributes to our limited success in maintaining patients within the therapeutic range," said Rose, who is also a core investigator in the Center for Health Quality, Outcomes and Economic Research at Bedford VA Medical Center in Massachusetts. "Previous studies have clearly shown that time spent outside the therapeutic range contributes to more adverse events for patients, such as stroke and gastrointestinal hemorrhage. Therefore, increasing the time in the therapeutic range is of utmost importance."

More information

The U.S. National Library of Medicine has more about warfarin.



-- Kevin McKeever



SOURCE: Boston University School of Medicine, news release, Dec. 22, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Study shows optimal dose management of warfarin improves anticoagulation control
2. Doctors Receive Bonuses for Providing Optimal Care to Patients Through Bridges to Excellence
3. Penn scientists show how body determines optimal amount of germ-fighting B cells
4. New National Patient and Surgeon Surveys Show Post-Surgical Care Critical to Optimal Weight Loss After Bariatric Surgery
5. Statement on CDC Announcement That 70 Percent of the U. S. Population Now Receives Optimally Fluoridated Water By Mark J. Feldman, DMD, President, American Dental Association
6. High-Performing Sales Forces Share Key Practices to Achieve Optimal Performance
7. eHealth Initiative and the Center for Improving Medication Management to Present Report Detailing Both Impact of E-Prescriptions on U.S. Health Care System and Guidelines for Achieving Optimal Results
8. Medco, Healthways Launch Center for Health Action to Deliver Optimal Health(TM)
9. Optimal Readings Selected to Present at CEDs 25th Annual Venture Conference
10. Optimal Readings Appoints Operations Veteran Rita Edwards as SVP Clinical Operations
11. Navigenics(TM) Launches Health Compass Service, a Personal Genetic Assessment for Optimal Health
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Optimal Warfarin Dosing Improves Anticoagulation Control
(Date:1/17/2017)... Lehi, Utah (PRWEB) , ... January 17, 2017 ... ... provider of accredited, online continuing education for EMS and firefighting professionals, has released ... Training (VILT) Solution. These new courses are taught live in an online classroom ...
(Date:1/17/2017)... TEXAS (PRWEB) , ... January 17, 2017 , ... ... provider, today announced its partnership with Sigfox in the U.S.A. to ... cities nationwide including new offerings on large-scale environmental sensor deployments such as ...
(Date:1/17/2017)... ... January 17, 2017 , ... Livionex, Inc., a Silicon Valley healthcare company focused ... study for its dental gel that shows significant reduction in plaque levels and gum ... The study was conducted at the Beckman Laser Institute at UC Irvine and has ...
(Date:1/17/2017)... , ... January 17, 2017 , ... ... private companies and ranked among the top US security companies for consecutive years, ... This announcement brings a year-long independent board nomination process to a close ...
(Date:1/16/2017)... ... January 17, 2017 , ... ... an internationally recognized leader in the fast-casual category, announces a hearty and wholesome ... Good Egg Breakfast Sandwich, Turkey Mash-Up Sandwich, Cranberry Crunch & Honey Parfait, Slow ...
Breaking Medicine News(10 mins):
(Date:1/17/2017)... Jan. 17, 2017 EU5 Glucose Monitoring Market ... report, "EU5 Glucose Monitoring Market Outlook to 2022", provides ... The report provides value, in millions of US dollars, ... segments - Blood Glucose Meters, Blood Glucose Test Strips ... and distribution shares data for each of these market ...
(Date:1/17/2017)... Jan. 17, 2017 Paragon Bioservices received a ... development services for a variety of National ... medical product development activities. The IDIQ mechanism will ... for task order awards up to $159 million. ... manufacturing and process development of biopharmaceuticals, is one ...
(Date:1/17/2017)... 2017  Pennsylvania Secretary of Health Dr. ... marijuana growers/processors and dispensaries are now available on ... Permit applications will be accepted from February 20 ... an important step forward in getting this valuable ... Murphy said. "We,ve developed a thorough application that ...
Breaking Medicine Technology: