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OpportunityAnalyzer: Nonalcoholic Steatohepatitis (NASH) - Opportunity Analysis and Forecasts to 2017
Date:10/25/2013

Rockville, MD (PRWEB) October 25, 2013

OpportunityAnalyzer: Nonalcoholic Steatohepatitis (NASH) - Opportunity Analysis and Forecasts to 2017

The level of unmet needs for NASH, including both environmental and clinical, is high and includes patient awareness, physician education, and approved therapies specific to NASH. These issues compound the reasons why the NASH market space is very sparse. A series of unknowns exist for the disease, due to its heterogeneous nature, and its slow progression poses problems for drug development.

Vitamin E, the current goldstandard therapy, dominates what little drug therapy NASH market there is. We expect Genfit’s small molecule GFT505 to claim patient share within the diabetic subpopulation, and Intercept Pharmaceuticals/DSP’s small molecule OCA to claim patients in all subpopulations, thus giving it an advantage. These products will likely solve the top unmet need - the dire need for an approved therapy for NASH.

The growing global rate of obesity and diabetes will boost the NASH market from $233 million in 2012 to $863 million by 2017, at a significant CAGR of 30%. The US will have the largest share of the market, contributing $827 million towards global sales, followed by the five major European markets - France, Germany, Italy, Spain and the UK. Currently, there are 29.3 million prevalent cases of NASH across these six major markets.

Dina Rufo, MS, GlobalData's Analyst covering Immunology, says: “Since there is neither cure, nor one specific therapy currently available for NASH, R&D strategies in this market space are complicated. Challenges range from unraveling the pathophysiology of NASH and designing diagnostic tools for more accurate diagnosis and staging, to the design of clinical trials. Furthermore, the level of unmet needs for NASH, including both environmental and clinical, is high and requires patient awareness and physician education.&quo
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