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OpportunityAnalyzer: Acute Myeloid Leukemia (AML) - Opportunity Analysis and Forecasts to 2017

ssment 189
10.4 Top Line Five-Year Forecast 190
10.4.1 US 192
10.4.2 5EU 194
11 Appendix 197
11.1 Bibliography 197
11.2 Abbreviations 215
11.3 Methodology 217
11.4 Forecasting Methodology 217
11.4.1 Diagnosed AML Patients 217
11.4.2 Percent Drug-treated Patients 218
11.4.3 Drugs Included in Each Therapeutic Class 218
11.4.4 Launch and Patent Expiry Dates 218
11.4.5 General Pricing Assumptions 219
11.4.6 Individual Drug Assumptions 220
11.4.7 Generic Erosion 223
11.4.8 Pricing of Pipeline Agents 223
11.5 Physicians and Specialists Included in this Study 224
11.6 About the Authors 226
11.6.1 Authors 226
11.6.2 Epidemiologist 227
11.6.3 Global Head of Healthcare 227
11.7 About GlobalData 228
11.8 Disclaimer 228

1.1 List of Tables

Table 1: Classification of AML Subtypes – WHO System 22
Table 2: Common Cytogenetic Abnormalities in AML 24
Table 3: Symptoms of AML 31
Table 4: Risk Factors and Comorbidities for AML in Adults 34
Table 5: Estimated Frequencies of Cytogenetic Abnormalities in AML 44
Table 6: Risk Group Classification Guidelines 45
Table 7: 6MM, Sources of AML Incidence 46
Table 8: 6MM, Incident Cases of AML, Men and Women Aged ?20 Years, N, Selected Years, 2012–2022 58
Table 9: 6MM, Incident Cases of AML by Age, Men and Women, N (row %), 2012 60
Table 10: 6MM, Incident Cases of AML by Sex, N (Row %), 2012 62
Table 11: 6MM, Incident Cases of APL, Men and Women Aged ?20 Years, N (Column %), Selected Years, 2012–2022 65
Table 12: 6MM, Incident Cases of MDS/Therapy-related AML, Men and Women Aged ?20 Years, N (Column %), Selected Years 2012–2022 66
Table 13: 6MM, Incident Cases of AML Subtypes by Age, Men and Women, N (Row % in Each Subtype), 2012 68
Table 14: 6MM, Incident Cases of AML with FLT3 Mut

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