Navigation Links
Opioid overdose prevention programs may reduce deaths, reports Journal of Addiction Medicine
Date:6/3/2014

June 3, 2014 Community opioid overdose prevention programs (OOPPs)including the use of naloxone for rapid drug reversalcan improve bystander responses to overdose of heroin and related drugs, according to a review in the June Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health . Based on the available evidence, "Bystanders (mostly opioid users) can and will use naloxone to reverse opioid overdoses when properly trained, andthis training can be done successfully through OOPPs," write Dr. Christine M. Wilder and colleagues of University of Cincinnati School of Medicine. But higher-quality research is needed to determine whether OOPPs can meet the goal of reducing deaths from opioid overdose.

Initial Results from OOPPsAre They Working?

There is growing interest in OOPPs to fight the rising number of deaths from overdose of opioids, including heroin and prescription painkillers. In these programs, kits containing naloxonethe generic name for Narcan, a drug that can rapidly reverse the effects of opioidsare distributed directly to patients at risk for overdose. Naloxone kits and training are often delivered in conjunction with needle exchange programs.

Dr. Wilder and colleagues identified and analyzed the results of 19 published studies evaluating OOPPs. The training programs included recognition, prevention, and risk factors for overdose; and how to respond to an overdose, including naloxone administration. Naloxone was usually given by injection, but sometimes by nasal administration.

Fourteen studies provided follow-up data on more than 9,000 OOPP participants. Nearly half of patients participating in OOPP programs had experienced an overdose during their lifetime, and about 80 percent had witnessed an overdose.

Eighteen studies provided data on nearly 1,950 naloxone administrations. When naloxone was given in response to an overdose, the person giving it was usually also an opioid user.

Eleven studies reported 100 percent survival; the rest reported survival rates of 83 to 96 percent. Two studies provided data suggesting that OOPPs were associated with community-wide reductions in opioid overdose deaths. The studies also provided information on 12 unsuccessful administrations, in which naloxone did not reverse the overdose for various reasons.

Need for More Research on OOPP Implementation and Effectiveness

Studies suggested that OOPP training increased bystanders' knowledge of overdose prevention and risk factors. Training also increased the use of appropriate overdose strategiesalthough many bystanders continued to use inappropriate strategies as well. Training didn't seem to increase bystanders' willingness to call EMS.

Many communities have established or are interested in establishing OOPPs to help stem the rising tide of deaths from opioid overdose. However, there are continued questions about the implementation and effectiveness of these programs. So far, research studies on OOPPs have been limited in number and quality.

An accompanying article discusses the experience of establishing an OOPP at one substance use disorders treatment center. The experience highlights some of the challenges to introducing this new approachfor example, getting "buy-in" from addiction center professionals and staff.

"OOPP participation is associated with overdose reversals, increased knowledge and ability to respond appropriately in an overdose situation, and the ability of non-medical bystanders to safely administer naloxone," Wilder and coauthors conclude. While naloxone is clearly life-saving in individual cases, more research will be needed to establish whether providing opioid users with overdose training and naloxone kits is an effective way to reduce the number of overdose deaths in the community. The authors emphasize the need for "well-designed studies" to assess the true impact on overdose deaths, how best to integrate OOPPs into current practice, and the benefits of OOPPs at the population level.


'/>"/>

Contact: Connie Hughes
Connie.Hughes@wolterskluwer.com
646-674-6348
Wolters Kluwer Health
Source:Eurekalert

Related medicine news :

1. A new target for alcoholism treatment: Kappa opioid receptors
2. Extended-release medication offers promise for treating alcohol, opioid dependence
3. HHS leaders call for expanded use of medications to combat opioid overdose epidemic
4. Researchers identify similarities between HIV/AIDS and opioid addiction epidemics
5. Tested a drug that strengthens the analgesic effect of opioids without increasing constipation
6. Prescriptions for opioids stabilizing after fivefold increase in 10-year span
7. Webinar: WCRI and Brandeis University Discuss Opioids
8. Proportion of opioid treatment programs offering on-site testing for HIV and STIs declines
9. VitaPro Labs Launches New Withdrawal Aid System at WithdrawalAid.com, a Supplement Proven To Ease Opioid Withdrawal Symptoms
10. Prescription opioid abusers prefer to get high on oxycodone and hydrocodone
11. Modern Medical’s Opioid Defense Manager Sees Measureable Results in Just 12 Months.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2017)... ... April 28, 2017 , ... Accreditation Commission for ... Care Association of America (HCAOA). This agreement allows HCAOA members to receive special ... as discounts on Accreditation University (AU) educational resources that help prepare HCAOA members ...
(Date:4/28/2017)... , ... April 28, 2017 , ... Horizon Blue Cross ... the company’s credit rating of “A” and its outlook as “stable.” At the same ... reserves, which have fallen in recent years, dip below “capital adequacy” thresholds required for ...
(Date:4/28/2017)... , ... April 28, 2017 , ... ... Replace tubes . These lamps offer an instant energy-saving solution for F32T8 fluorescent ... rewire fixtures or disconnect ballasts. These 50,000 hour rated lamps utilize the existing ...
(Date:4/28/2017)... ... April 28, 2017 , ... The Texas Cord Blood Bank (TCBB), a program ... delivery team at Women’s Hospital at Renaissance in Edinburg for their outstanding efforts in ... and decide to donate. , “Women’s Hospital at Renaissance has been a collection ...
(Date:4/28/2017)... ... April 28, 2017 , ... Bill Howe started his sewer and drain ... After Tina Howe joined the team, the Bill Howe brand was born and they ... rates, and giving back to the San Diego community in which they worked, lived ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... DUBLIN , April 20, 2017 Research ... Delivery Technologies - Innovation Driven by Rapidly Expanding Injectables Market and ... to their offering. ... market for drug delivery technologies will rise from USD 20 Billion ... Global Drug Delivery Technologies - Innovation Driven by Rapidly ...
(Date:4/20/2017)... Research and Markets has announced the ... Application Analysis, Regional Outlook, Growth Trends, Key Players, Competitive Strategies ... ... was valued at US$ 7,167.6 Mn in 2015, and is ... a CAGR of 5.6% from 2016 to 2024. ...
(Date:4/19/2017)... 19, 2017 /PRNewswire/ - CRH Medical Corporation (TSX: CRH) (NYSE MKT: CRHM) (the ... Co. Healthcare Investor Conference 2017 at the Sheraton Hotel in ... Chief Executive Officer of the Company is scheduled to present on ... Bear and the Chairman of the Board, Tony Holler ... ...
Breaking Medicine Technology: