Navigation Links
Oosight Imaging System Enables a Breakthrough: The Viable Transfer of Genetic Material for Stem Cell Nuclear Reprogramming in Primates
Date:11/16/2007

WOBURN, Mass., Nov. 16 /PRNewswire/ -- Cambridge Research & Instrumentation, Inc. (CRi) announced today that their Oosight(TM) Imaging System has been used by Dr. Shoukhrat Mitalipov to successfully transfer nuclear genetic material from somatic cells from a 10-year-old male macaque to enucleated eggs to generate cloned macaque embryos. In a soon to be published Nature paper, Dr. Mitalipov of the Oregon National Primate Research Center and the Oregon Stem Cell Center, reports that use of Oosight's polarized light imaging technology allowed him to visualize and extract nuclear material from somatic cells and then transfer that material to enucleated eggs without perturbing the viability of the recipient cells. Further, he was able to extract viable stem cells from the embryos and stimulate them to develop into mature heart and nerve cell clones. This is the first report with convincing evidence that nuclear reprogramming is feasible in primates. The ultimate goal is to develop clones of patient-specific stem cells that can be use to treat life-limiting conditions such as Diabetes, Parkinson's, Huntington's and cystic fibrosis.

"Enucleation with Oosight improves primate somatic cell nuclear transfer development to blastocyst," says Dr. Shoukhrat Mitalipov. The current results would not have been possible using the traditional method of Hoechst-UV enucleation.

The Oosight is a real-time, non-invasive imaging system that utilizes proprietary polarized light imaging methods. It dramatically improves somatic cell nuclear transfer efficiency through imaging and identification of structures (nuclear material) that are otherwise invisible with traditional contrast enhancement. "We're extremely excited to play a role in this exciting research advance by providing the enabling imaging technology used by Dr. Mitalipov," says Cathy Boutin, Marketing Manager of Polarized Light Imaging Systems at CRi. "This system was designed and developed to provide real-time, non-invasive imaging of live cells that maintains viability, the key to success."

"As a company, CRi is focused on developing advanced imaging solutions that are enabling our customers to breakthrough roadblocks in the development of new therapies, including the promise of translational, personalized and regenerative medicine," states George Abe, CRi's President and CEO. "Our whole team is driven to support the work of scientists and medical professionals such as Dr. Mitalipov."

CRi is a Boston-based biomedical imaging company providing innovative optical imaging solutions to our customers for more than 20 years. Our multidisciplinary team is dedicated to working with our academic and commercial customers to provide high-value solutions. We provide comprehensive imaging and analysis solutions that enable the user to investigate and characterize biological phenotypes while preserving spatial context. With over 80 patents issued and pending, CRi's solution platforms encompass sub-cellular, cellular and whole animal applications. Our innovations are being utilized around the world to enable new breakthroughs in research, health and medicine. For more information visit our website at http://www.cri-inc.com or contact:

David Daniels, Ph.D.

Director of Marketing

CRi

35-B Cabot Road, Woburn, MA 01801 USA

Tel: 1-781-935-9099, extension 149

E-mail: ddaniels@cri-inc.com


'/>"/>
SOURCE Cambridge Research & Instrumentation
Copyright©2007 PR Newswire.
All rights reserved

Related medicine news :

1. Brain imaging reveals breakdown of normal emotional processing
2. Clarity Imaging International, Inc. Rolls Out Mobile DEXA Program
3. Fry Construction Selected for High-Profile Medical Imaging Project
4. Elbit Medical Imaging Ltd. Announces Publication of a Prospectus in Israel
5. Ultrasonix Adds Global Medical Imaging Into Its North American Sales Force
6. Imaging Software Helps Track, Treat Injured Brains
7. SNM seeks novel approaches to molecular imaging to showcase at annual meeting
8. SNM seeks novel approaches to molecular imaging to showcase at annual meeting
9. Revision: Ziehm Imaging and BrainLAB Announce Partnership for Intra-Operative 3D Imaging and Computer Assisted Surgery (CAS)
10. Brain Imaging Expert Recruited to Study Autism at The Childrens Hospital of Philadelphia
11. Medical Imaging Revolutionizes Modern Medicine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... Oklahoma City, Oklahoma (PRWEB) , ... June 25, ... ... to helping both athletes and non-athletes recover from injury. Recently, he has implemented ... for the Oklahoma City area —Johnson is one of the first doctors to ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits ... terms of the latter, setting the bar too high can result in disappointment, perhaps ... slow progress toward their goal. , Research from PsychTests.com reveals that ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic events may suffer ... unhealthy avenues, such as drug or alcohol abuse, as a coping mechanism. To avoid ... healthy coping following a traumatic event. , Trauma sufferers tend to feel a range ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, ... at his family verbally and physically. , “When something upset him, he couldn’t control his ... it. He would throw rocks at my other children and say he was going to ...
(Date:6/24/2016)... ... , ... Global law firm Greenberg Traurig, P.A. announced that 20 Florida attorneys ... peers for this recognition are considered among the top 2 percent of lawyers practicing ... members of this year’s Legal Elite Hall of Fame: Miami Shareholders Mark D. ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 ... Markets has announced the addition of the " ... offering. This ... and provides an updated review, including its applications in ... the total market, which includes three main industries: pharmaceutical ...
(Date:6/24/2016)... 24, 2016 The Academy of Managed Care ... that would allow biopharmaceutical companies to more easily ... make formulary and coverage decisions, a move that addresses ... medicines. The recommendations address restrictions in the ... the drug label, a prohibition that hinders decision makers ...
(Date:6/24/2016)... Calif. , June 24, 2016  American Respiratory Labs (ARL), ... is now able to perform sophisticated lung assessments in patients, homes, ... , Inc. Patients are no longer limited to ... EasyOne PRO ® , ARL patients like Jeanne R. of ... in the comfort of her own home. ...
Breaking Medicine Technology: