Navigation Links
Online tool supports more dialogue on prostate cancer risk
Date:2/4/2008

Toronto (February 4, 2008) A comprehensive, clinical nomogram tool, the Sunnybrook Prostate Cancer Risk Calculator the first to use all known risk factors for prostate cancer is available online to help men determine individual prostate cancer risk in consultation with their primary care physician. A nomogram is a statistical model to determine risk for disease based on risk factors using a table and chart format.

"This tool facilitates proactive dialogue between patients and their primary care physicians about prostate cancer risk, and management and treatment options," says Dr. Robert Nam, lead investigator and urologic oncologist, Odette Cancer Centre, Sunnybrook. In addition to helping men avoid unnecessary biopsies this nomogram better detects prostate cancer at an earlier more curable stage and helps identify high risk patients who may need to make immediate dietary and lifestyle changes and need repeat biopsies.

Sunnybrook researchers developed and validated the nomogram with 3,108 Canadian men including a subset of 408 volunteers with normal PSA (prostate specific antigen) levels who underwent a prostate biopsy. Of the 3,108 men, 42 per cent were diagnosed with prostate cancer. The nomogram was shown to perform better than conventional screening with PSA and DRE (digital rectal exam) alone, especially for patients with a known normal PSA level. Among the 408 men with a normal PSA, 24 per cent were diagnosed with prostate cancer. Further evaluation of the nomogram is underway with a multi-institutional, cross-Canada study group of another 5,000 men.

At age 70, Colin Grahams PSA level was considered normal (less than or equal to 4.0 ng/ML). When the nomogram was used to assess all his risk factors, Dr. Nam recommended a prostate biopsy. The biopsy diagnosed aggressive prostate cancer and Colin underwent immediate and successful treatment through surgery. "I cant express enough the relief I felt, knowing things were caught in time," says Graham, "and though this cancer was removed successfully, because I know my risk, Im also aware I still need to be monitored."

"In Colins case, though his PSA was normal, a biopsy was justified based on the nomogram. On the other hand, in the case of an older patient with a high PSA level, if the nomogram predicts a low chance of having aggressive prostate cancer, then it would be reasonable to forego a biopsy," says Dr. Nam, assistant professor, department of surgery, University of Toronto.

Unlike current prostate cancer nomograms, this nomogram evaluates the risk of having prostate cancer in patients undergoing PSA screening. Known risk factors and tumour markers used are age, family, history of prostate cancer, ethnicity, urinary symptoms, PSA, free:total PSA ratio, and DRE (performed by the primary care physician). The Sunnybrook Prostate Cancer Risk Calculator is best used in collaboration with an individuals primary care physician. If a patient determines he is at risk for aggressive prostate cancer, he can discuss management and treatment options in consultation with his primary care physician.


'/>"/>

Contact: Natalie Chung-Sayers
natalie.chung-sayers@sunnybrook.ca
416-480-4040
Sunnybrook Health Sciences Centre
Source:Eurekalert

Related medicine news :

1. MGMA Hires 90octane for Online Lead Generation Program
2. Celebrities Encourage Women to Take Steps for Heart Health Through Online Red Shoe Charity Auction
3. First-of-Its-Kind National Online Survey Uncovers Obstacles to Comprehensive Healthcare for People With Schizophrenia
4. MWW Group Selected by First-Ever Online Doctor Evaluation Service Vitals.com
5. WebTribes Offers Online Home for Those with Illnesses
6. Emmy(R)- and Golden Globe(R)-Nominated Actress Marcia Cross and Lifetime Television Deliver 20 Million Online Petition Signatures to Capitol Hill to Urge Congress to Stop Drive-Through Mastectomies
7. Snap Fitness Launches Partnerships with Leading Online Health & Fitness Companies
8. Battling potential disease outbreaks online
9. Local Oncology Group Leads Online Effort to Revolutionize Cancer Care
10. Simple online methods increase physician disease reporting
11. JCI online early table of contents: Jan. 10 2008
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/20/2017)... SANTA CLARA, CA (PRWEB) , ... July 20, ... ... some form of travel protection services since 2014, top travel insurance solution company ... agents the tools to sell all major international travel insurance products online, under ...
(Date:7/20/2017)... ... 2017 , ... A local summer theatre camp is celebrating ... support fine arts programs in Chester County’s Elementary Schools. In late June, students ... , More than 850 people attended the two performances, an increase from ...
(Date:7/20/2017)... ... ... Med Tech Solutions (MTS), a leading health care cloud computing company, recently announced ... move that will help the company better serve its clients and promote continued growth. ... to help MTS expand its presence in the Midwest and deepen MTS’ ...
(Date:7/20/2017)... ... 2017 , ... A July 5th article on Reuters Health News ... received a body contouring procedure reported experiencing a better quality of life, compared to ... provides both types of procedures, notes that this report jibes with what they regularly ...
(Date:7/20/2017)... ... ... the Buffalo and Her Adventures”: a collection of heartwarming children’s stories. “Lucky the Buffalo ... Jr. was born in Toledo, Ohio. He attended Woodward High School. He earned ... to a brilliant woman with a caring heart named Tiina, who is a hospice nurse. ...
Breaking Medicine News(10 mins):
(Date:7/11/2017)... Oramed Pharmaceuticals Inc. (NASDAQ: ORMP ) ( ... development of oral drug delivery systems, announced today that ... to schedule an End-of-Phase II meeting with Oramed for ... insulin capsule ORMD-0801 in the treatment of type 2 ... endpoints by indicating a statistically significant lowering of glucose ...
(Date:7/10/2017)...  The tenth annual BioPharm America™ will ... at the Sheraton Boston Hotel, September 26–27. The event ... decision makers and innovative biotech startup companies. The event ... two impactful days. BioPharm America is now part of ... opportunities with 4,500+ life science industry influencers participating in ...
(Date:7/5/2017)... , July 5, 2017 ... www.oramed.com ), a clinical-stage pharmaceutical company focused ... that it has received approval from the Israel Securities Authority ... Exchange (TASE). Oramed common stock will commence trading on the ... on the current market capitalization of the Company, it is ...
Breaking Medicine Technology: