Navigation Links
Online tool supports more dialogue on prostate cancer risk
Date:2/4/2008

Toronto (February 4, 2008) A comprehensive, clinical nomogram tool, the Sunnybrook Prostate Cancer Risk Calculator the first to use all known risk factors for prostate cancer is available online to help men determine individual prostate cancer risk in consultation with their primary care physician. A nomogram is a statistical model to determine risk for disease based on risk factors using a table and chart format.

"This tool facilitates proactive dialogue between patients and their primary care physicians about prostate cancer risk, and management and treatment options," says Dr. Robert Nam, lead investigator and urologic oncologist, Odette Cancer Centre, Sunnybrook. In addition to helping men avoid unnecessary biopsies this nomogram better detects prostate cancer at an earlier more curable stage and helps identify high risk patients who may need to make immediate dietary and lifestyle changes and need repeat biopsies.

Sunnybrook researchers developed and validated the nomogram with 3,108 Canadian men including a subset of 408 volunteers with normal PSA (prostate specific antigen) levels who underwent a prostate biopsy. Of the 3,108 men, 42 per cent were diagnosed with prostate cancer. The nomogram was shown to perform better than conventional screening with PSA and DRE (digital rectal exam) alone, especially for patients with a known normal PSA level. Among the 408 men with a normal PSA, 24 per cent were diagnosed with prostate cancer. Further evaluation of the nomogram is underway with a multi-institutional, cross-Canada study group of another 5,000 men.

At age 70, Colin Grahams PSA level was considered normal (less than or equal to 4.0 ng/ML). When the nomogram was used to assess all his risk factors, Dr. Nam recommended a prostate biopsy. The biopsy diagnosed aggressive prostate cancer and Colin underwent immediate and successful treatment through surgery. "I cant express enough the relief I felt, knowing things were caught in time," says Graham, "and though this cancer was removed successfully, because I know my risk, Im also aware I still need to be monitored."

"In Colins case, though his PSA was normal, a biopsy was justified based on the nomogram. On the other hand, in the case of an older patient with a high PSA level, if the nomogram predicts a low chance of having aggressive prostate cancer, then it would be reasonable to forego a biopsy," says Dr. Nam, assistant professor, department of surgery, University of Toronto.

Unlike current prostate cancer nomograms, this nomogram evaluates the risk of having prostate cancer in patients undergoing PSA screening. Known risk factors and tumour markers used are age, family, history of prostate cancer, ethnicity, urinary symptoms, PSA, free:total PSA ratio, and DRE (performed by the primary care physician). The Sunnybrook Prostate Cancer Risk Calculator is best used in collaboration with an individuals primary care physician. If a patient determines he is at risk for aggressive prostate cancer, he can discuss management and treatment options in consultation with his primary care physician.


'/>"/>

Contact: Natalie Chung-Sayers
natalie.chung-sayers@sunnybrook.ca
416-480-4040
Sunnybrook Health Sciences Centre
Source:Eurekalert

Related medicine news :

1. MGMA Hires 90octane for Online Lead Generation Program
2. Celebrities Encourage Women to Take Steps for Heart Health Through Online Red Shoe Charity Auction
3. First-of-Its-Kind National Online Survey Uncovers Obstacles to Comprehensive Healthcare for People With Schizophrenia
4. MWW Group Selected by First-Ever Online Doctor Evaluation Service Vitals.com
5. WebTribes Offers Online Home for Those with Illnesses
6. Emmy(R)- and Golden Globe(R)-Nominated Actress Marcia Cross and Lifetime Television Deliver 20 Million Online Petition Signatures to Capitol Hill to Urge Congress to Stop Drive-Through Mastectomies
7. Snap Fitness Launches Partnerships with Leading Online Health & Fitness Companies
8. Battling potential disease outbreaks online
9. Local Oncology Group Leads Online Effort to Revolutionize Cancer Care
10. Simple online methods increase physician disease reporting
11. JCI online early table of contents: Jan. 10 2008
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 26, 2016 , ... On June 10-11, 2016, A ... 2016 Cereal Festival and World’s Longest Breakfast Table in Battle Creek, MI, where the ... history as home to some of the world’s leading providers of cereal and other ...
(Date:6/25/2016)... , ... June 25, 2016 , ... ... policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at ... on several important health care topics including advance care planning, healthcare costs and ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... As a ... Magna Cum Laude and his M.D from the David Geffen School of Medicine at ... returned to Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars ...
(Date:6/24/2016)... ... ... Those who have experienced traumatic events may suffer from a complex set of ... or alcohol abuse, as a coping mechanism. To avoid this pain and suffering, Serenity ... event. , Trauma sufferers tend to feel a range of emotions, from depression, guilt, ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda Cheng, an ... Cheng has extensive experience with all areas of orthodontics, including robotic Suresmile technology, ... , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It can be ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... June 24, 2016 Research ... "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" ... In-Mold Electronics, Smart Skin, Structural Health ... Structural electronics involves electronic and/or electrical ... structures, replacing dumb structures such as vehicle bodies ...
(Date:6/24/2016)... Research and Markets has announced the addition of ... report to their offering. ... The World Market for Companion Diagnostics covers the world market ... the report includes the following: , World ... Region (N. America, EU, ROW), 2015-2020 , World IVD ...
(Date:6/24/2016)... , June 24, 2016  Arkis BioSciences, ... less invasive and more durable cerebrospinal fluid treatments, ... funding.  The Series-A funding is led by Innova ... Fund, and other private investors.  Arkis, new financing ... instrumentation and the market release of its in-licensed ...
Breaking Medicine Technology: