Navigation Links
One-third of psoriatic arthritis patients are not receiving optimal dosing of adalimumab
Date:6/11/2014

imab dose with subsequent step up therapy seems to be an efficient strategy.

Danish patients received higher infliximab doses than Icelandic patients at baseline (median (IQR) 3.1 (3.0-3.8) mg/kg vs. 2.3 (2.1-2.9) mg/kg, p<0.05) and after 12 months (3.3 (3.0-4.5) mg/kg vs. 2.9 (2.2-3.5) mg/kg, p<0.0001). In Danish patients, the start dose was ≤3 mg/kg in 110 patients (29%), 3-5 mg/kg in 157(42%), ≥5 mg/kg in 38(10%) and unregistered in 71(19%). In Icelandic patients, the corresponding numbers were 64 (74%), 17 (27%), 0 (0%) and 5 (6%). Patients with higher body weight received lower infliximab doses per kg.

"Despite these important differences between Icelandic and Danish patients, they were found to have similar one-year response rates," said Dr Glintborg. After 12 months, 58% of Danish and 66% of Icelandic patients maintained treatment. In univariate analyses stratified by country, the time until dose escalation, ACR20/50/70 or EULAR-response rates, drug adherence and one-year's disease activity were independent of the baseline dose of infliximab," Dr Glintborg explained.

This was an observational cohort study based on the nationwide DANBIO and ICEBIO registries. Among the 1,589 psoriatic arthritis patients identified in the two registries, 462 patients (29%, 376 Danish, 86 Icelandic) received treatment with infliximab. Dose escalation was defined as an increase in either the dose and/or frequency. Treatment response was evaluated by ACR20/50/70 and EULAR-good-response after six months of treatment and disease activity after one year of treatment. Kaplan-Meier plots and regression analyses were performed to analyse adherence to treatment and to identify predictors of treatment response and adherence.


'/>"/>

Contact: EULAR Press Office
eularpressoffice@cohnwolfe.com
44-078-801-73209
European League Against Rheumatism
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. New autism definition may decrease diagnosis by one-third, Columbia University finds
2. Gene driver of Waldenstroms Macroglobulinemia in up to one-third of patients identified
3. More than one-third of populations worldwide may have low levels of vitamin D, study shows
4. CHADS2 risk score assigns over one-third of stroke patients to low or intermediate stroke risk
5. Pain relief technique cuts hospital stay by one-third for some surgical patients
6. Nearly one-third of children with autism also have ADHD
7. More than one-third of Texas women still receive unnecessary breast biopsy surgery
8. Only one-third of parents follow doctors orders for kids all of the time
9. Nearly One-Third of Kids With Food Allergies May Be Bullied
10. Streetcar tracks blamed in one-third of Toronto bike accidents
11. Surgical patient safety program lowers SSIs by one-third following colorectal operations
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/27/2014)... 2014 In a world enveloped ... sleep has lessened, and due to the intrusion ... of sleep has eroded. According to Web MD, ... job (Reference: http://www.webmd.com/sleep-disorders/features/sleep-deprivation-workplace ). This remarkably high ... an incalculable amount, leading not only to dissatisfied ...
(Date:11/27/2014)... "As a nurse I see patients every ... incontinence," said an inventor from Whiting, N.J. "I put ... to prevent leakage and keep them dry and comfortable." ... This prevents stains on pants, skirts and bottoms, which ... that the individual has time to get to the ...
(Date:11/27/2014)... 2014 (HealthDay News) -- Most babies and young children ... U.S. Food and Drug Administration says. Over-the-counter (OTC) ... children younger than 2 because they could cause serious ... American adults average about three colds a year, but ... cold, parents might want to give them pain relievers, ...
(Date:11/27/2014)... 2014 In order to enable people to ... designed an easy way to avoid touching a toilet seat ... created a prototype of the patent-pending Toilet Tamer, a device ... seat and/or lid in a more sanitary manner. It avoids ... germs. Overall, it promotes good hygiene and peace of mind. ...
(Date:11/27/2014)... Now that Thanksgiving is finally here ... Emassagechair.com has announced its eagerly awaited, once ... , Negotiating on behalf of their customers, and drawing ... Emassagechair.com has generated significant buzz in the industry with ... yet. , Shoppers are excited for significant savings available ...
Breaking Medicine News(10 mins):Health News:Research Shows Surprising Number of US Workers Affected by Lack of Sleep 2Health News:Steer Clear of Cold Meds for Babies, FDA Advises 2Health News:Emassagechair.com is Excited to Announce Their Biggest Discount Event of the Year, Starting the Day After Thanksgiving and Lasting Through The Holiday Weekend. 2Health News:Emassagechair.com is Excited to Announce Their Biggest Discount Event of the Year, Starting the Day After Thanksgiving and Lasting Through The Holiday Weekend. 3Health News:Emassagechair.com is Excited to Announce Their Biggest Discount Event of the Year, Starting the Day After Thanksgiving and Lasting Through The Holiday Weekend. 4
... - A University of Illinois researcher advises caution when ... country,s Latino adolescents and young adults. "When a ... a 90-minute program, the Latino students in my classes thought ... right!" said Marcela Raffaelli, a U of I professor of ...
... ... requirements with convenient and affordable online courses that are peer reviewed and state ... ... online career information resource and social networking Web site for physical therapy ...
... , ... Dr. Katherine Galina of City Dental, offers lifetime teeth bleaching services to new patients ... Los Angeles (PRWEB) February 22, ... City Dental announces their Free Bleaching for Life services. New patients who visit Dr. Galina ...
... ... ... ... ...
... , , ... ... ... ...
... Academy at the University of Gothenburg, Sweden and Karolinska ... genetic patterns of neuroblastoma, an aggressive form of childhood ... the treatment of this malignant disease, which mainly affects ... the respected scientific journal, Proceedings of the National ...
Cached Medicine News:Health News:Are Latino teens sexual risk takers? It's complicated, researcher says 2Health News:Are Latino teens sexual risk takers? It's complicated, researcher says 3Health News:DavisPTnetwork Partners with the Florida Physical Therapy Association to Provide Online Continuing Education 2Health News:LA Dentist, Dr. Katherine Galina, Offers Free Bleaching for Life 2Health News:57 Year-Old Grandmother Travels to Atacama Desert to Run First of Four Ultramarathons for Charity 2Health News:57 Year-Old Grandmother Travels to Atacama Desert to Run First of Four Ultramarathons for Charity 3Health News:57 Year-Old Grandmother Travels to Atacama Desert to Run First of Four Ultramarathons for Charity 4Health News:57 Year-Old Grandmother Travels to Atacama Desert to Run First of Four Ultramarathons for Charity 5Health News:57 Year-Old Grandmother Travels to Atacama Desert to Run First of Four Ultramarathons for Charity 6Health News:Remuda Ranch Programs for Eating and Anxiety Disorders Sponsors a Special Edition of the Award-Winning Documentary America The Beautiful 2Health News:Remuda Ranch Programs for Eating and Anxiety Disorders Sponsors a Special Edition of the Award-Winning Documentary America The Beautiful 3Health News:Remuda Ranch Programs for Eating and Anxiety Disorders Sponsors a Special Edition of the Award-Winning Documentary America The Beautiful 4Health News:Remuda Ranch Programs for Eating and Anxiety Disorders Sponsors a Special Edition of the Award-Winning Documentary America The Beautiful 5Health News:New DNA technique leads to a breakthrough in child cancer research 2
(Date:11/26/2014)... FRANCISCO , Nov. 25, 2014  goBalto, Inc., ... has been recognized as a winner of Red Herring,s ... a Global Top 100 North America award in 2013, ... international technology landscape. Red Herring,s Top 100 ... identifying promising new companies and entrepreneurs. Red Herring editors ...
(Date:11/26/2014)... 25, 2014 Nanomix Inc., (Nanomix), ... development of mobile diagnostic tests to enable ... and pre-hospital settings, today announced it has ... The certification was awarded by the British ... leading certification bodies. ISO ...
(Date:11/26/2014)... BOULDER, Colo. , Nov. 25, 2014 ... ARRY ) today announced that its Chief ... speak at the following upcoming conferences.  The ... conferences through webcasts on the Array BioPharma ... ConferenceDate:Wednesday, December 3, 2014Time:1:30 p.m.  Eastern Time ...
Breaking Medicine Technology:goBalto Selected as a 2014 Red Herring Top 100 Global Company 2goBalto Selected as a 2014 Red Herring Top 100 Global Company 3Nanomix Receives ISO 13485:2003 Certification 2
... CONCORD, N.H., Oct. 5 A new statewide prescription assistance ... New Hampshire Rx Card will offer savings of up to ... across the country. All New Hampshire residents are eligible to ... can download a "FREE" card by visiting www.nhrxcard.com ...
... 5 BioWa, Inc. announced today that it ... Co. Ltd. (Otsuka) to provide Otsuka with access ... development and commercialization of their antibody therapeutics with ... Japanese pharmaceutical POTELLIGENT® License was initiated in May, ...
Cached Medicine Technology:New Hampshire Rx Card Launching Statewide 2BioWa Announces Second Japanese License of POTELLIGENT(R) Technology to Otsuka Pharmaceutical 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: