Navigation Links
One-third of psoriatic arthritis patients are not receiving optimal dosing of adalimumab
Date:6/11/2014

imab dose with subsequent step up therapy seems to be an efficient strategy.

Danish patients received higher infliximab doses than Icelandic patients at baseline (median (IQR) 3.1 (3.0-3.8) mg/kg vs. 2.3 (2.1-2.9) mg/kg, p<0.05) and after 12 months (3.3 (3.0-4.5) mg/kg vs. 2.9 (2.2-3.5) mg/kg, p<0.0001). In Danish patients, the start dose was ≤3 mg/kg in 110 patients (29%), 3-5 mg/kg in 157(42%), ≥5 mg/kg in 38(10%) and unregistered in 71(19%). In Icelandic patients, the corresponding numbers were 64 (74%), 17 (27%), 0 (0%) and 5 (6%). Patients with higher body weight received lower infliximab doses per kg.

"Despite these important differences between Icelandic and Danish patients, they were found to have similar one-year response rates," said Dr Glintborg. After 12 months, 58% of Danish and 66% of Icelandic patients maintained treatment. In univariate analyses stratified by country, the time until dose escalation, ACR20/50/70 or EULAR-response rates, drug adherence and one-year's disease activity were independent of the baseline dose of infliximab," Dr Glintborg explained.

This was an observational cohort study based on the nationwide DANBIO and ICEBIO registries. Among the 1,589 psoriatic arthritis patients identified in the two registries, 462 patients (29%, 376 Danish, 86 Icelandic) received treatment with infliximab. Dose escalation was defined as an increase in either the dose and/or frequency. Treatment response was evaluated by ACR20/50/70 and EULAR-good-response after six months of treatment and disease activity after one year of treatment. Kaplan-Meier plots and regression analyses were performed to analyse adherence to treatment and to identify predictors of treatment response and adherence.


'/>"/>

Contact: EULAR Press Office
eularpressoffice@cohnwolfe.com
44-078-801-73209
European League Against Rheumatism
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. New autism definition may decrease diagnosis by one-third, Columbia University finds
2. Gene driver of Waldenstroms Macroglobulinemia in up to one-third of patients identified
3. More than one-third of populations worldwide may have low levels of vitamin D, study shows
4. CHADS2 risk score assigns over one-third of stroke patients to low or intermediate stroke risk
5. Pain relief technique cuts hospital stay by one-third for some surgical patients
6. Nearly one-third of children with autism also have ADHD
7. More than one-third of Texas women still receive unnecessary breast biopsy surgery
8. Only one-third of parents follow doctors orders for kids all of the time
9. Nearly One-Third of Kids With Food Allergies May Be Bullied
10. Streetcar tracks blamed in one-third of Toronto bike accidents
11. Surgical patient safety program lowers SSIs by one-third following colorectal operations
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... Principle Business Enterprises, a family owned ... top-of-the-line absorbent products. The company has recently made ... brand, Tranquility® Premium Protection absorbent products. The company ... its packaging a new look, and is currently working ... the public. , The new website, developed with Thread ...
(Date:10/20/2014)... PA (PRWEB) October 20, 2014 ... Matthew Voicheck as Assistant Director of their ... role in managing the innovative turnkey drug sourcing, ... , Matthew brings over 12 years of industry ... joins Myoderm at the peak of their international ...
(Date:10/20/2014)... Succeed is proud to announce that they ranked ... the Every Body Walk! campaign by Kaiser Permanente. ... encourages workers to be more active outside of the workplace. ... at the end of September, was a friendly competition between ... Participating companies gave their staff pedometers and each day, ...
(Date:10/20/2014)... 2014 National Teen Driver Safety Week is ... Academy of Pediatrics (Ohio AAP, http://www.ohioaap.org ) is joining ... of teen drivers to talk to their teens and always ... vehicle crashes are the leading cause of death for U.S. ... fatal crashes, and 859 (42%) of those teen drivers were ...
(Date:10/20/2014)... Unveiled at the Sept. 18 board meeting, The Center ... hospital ROI on membership dues at 12.5. In other words, ... in value to member hospitals. The calculation used to determine ... , “This is the first time we’ve actually been ... methodology is really sound,” said Bill Ryan , president ...
Breaking Medicine News(10 mins):Health News:Tranquility® Premium Protection Incontinence Products Releases New Logo and Website 2Health News:Myoderm Hires Matthew Voicheck to Lead Turnkey Drug Sourcing Service 2Health News:Succeed Management Solutions, LLC Competes in Walking Challenge and Achieves 12th Place in Portland 2Health News:Ohio AAP Promotes National Teen Driver Safety Week 2Health News:Scorecard Estimates Hospital ROI at $12.50 for every $1 Spent on Dues 2Health News:Scorecard Estimates Hospital ROI at $12.50 for every $1 Spent on Dues 3Health News:Scorecard Estimates Hospital ROI at $12.50 for every $1 Spent on Dues 4
... River Valley Water Supply Project's key agenda is to transfer ... heavily populated areas in the red river drainage basin. // ... proposition, due to a perceptible risk of foreign biota filling ... of the Earth Canada, feels that a task of such ...
... pneumonia, bronchitis and other infections. Bristol-Myers Squibb Co. (BMY) ... Food and Drug Administration said that the drug would ... blood-sugar changes due to this drug. ,This ... serious cases of hypoglycemia (low blood sugar) and hyperglycemia ...
... Ranbaxy has introduced a diagnostic test for Bird Flu that ... accurate results within 24 hours. Named as RT-PCR test, // ... be available in a day. Certainly a blessing in the ... available to check for Bird Flu report results only after ...
... of dance lovers in discos has been found to work ... was first synthesised in 1910. It was patented two years ... suppressant. ,The study finds that loud music exacerbates ... was conducted by Italian scientists on rats. Who were given ...
... on either couple, men seem to be more vulnerable, according ... his research team from Harvard Medical School. ,The ... the risk of illness in the other partner in a ... ,They found that when a spouse was hospitalized, ...
... Medicines Racket is growing at alarming proportions. The United Nations ... wide initiative , by way of a task force team ... of counterfeit drugs. A three day meeting is underway in ... - Pharamaceutical companies, Regulatory bodies and groups which represent the ...
Cached Medicine News:Health News:The effects of Ecstasy more pronounced in presence of music 2
(Date:10/20/2014)... -- Indianapolis interventional medical device maker NICO Corporation ... visualization leader Synaptive Medical announced today ... that they have joined forces to integrate their ... the first of its kind and will make ... BrainPath® interventional access technology and Synaptive,s BrightMatter™ real-time ...
(Date:10/20/2014)...  AnaptysBio, Inc., a leader in the discovery ... appointment of Marco Londei , M.D. as ... preclinical and clinical development of AnaptysBio,s proprietary antibody ... welcome Dr. Londei to AnaptysBio,s executive leadership team," ... Executive Officer of AnaptysBio. "Dr. Londei,s extensive expertise ...
(Date:10/20/2014)... -- Norgine B.V. today announced that the ... preparation, NER1006, presented at the 79 th Annual ... Philadelphia, PA , has met its ... endpoint of cleansing success. The study demonstrated high quality ... in screening colonoscopy patients. [1] (Logo: ...
Breaking Medicine Technology:Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 2Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 3Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 4Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 5AnaptysBio Appoints Dr. Marco Londei to Newly Created Chief Development Officer Position Clinical Immunologist to Lead AnaptysBio's Pipeline Advancement 2Positive Results from Phase II Data Show NER1006 Achieves High Quality Bowel Cleansing Efficacy 2
... 2011 The Radiosurgery Society™ (RSS), a non-profit organization ... clinical practice of stereotactic body radiotherapy (SBRT) and radiosurgery ... at the La Costa Resort in Carlsbad, Calif.   ... Radiosurgery Society has been expanded to serve as a ...
... To reward loyal shoppers, CVS/pharmacy today ... multiple free gift cards just by shopping for essentials ... began on Sunday October 16 and will go through ... can earn $10 gift cards to Macy,s, Gap, Applebee,s, ...
Cached Medicine Technology:Announcing The Radiosurgery Society™ And Its 2012 SRS/SBRT Scientific Meeting 2Announcing The Radiosurgery Society™ And Its 2012 SRS/SBRT Scientific Meeting 3Save Big This Fall with CVS/pharmacy's Free Gift Cards Promotion 2Save Big This Fall with CVS/pharmacy's Free Gift Cards Promotion 3
Straight 9 mm downcutting Royce blade. Can be placed in closed handle for protection. Handle length folded 109 mm, 4.3 inches. Blade can be set automatically and rigidly at any point from straight to...
Duckbill. 3.5 mm tip. Light curve....
Duckbill type, sharp. 3 mm x 8 mm curved blade. Octagonal handle....
4 mm x 9 mm tip....
Medicine Products: