Navigation Links
One Strain Behind Epidemic of Staph Infections
Date:1/21/2008

Government study found most MRSA infections in community linked to single evolving bacterium

MONDAY, Jan. 21 (HealthDay News) -- A single strain of an evolving bacterium has been responsible for most of the community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections that have spread rapidly in the United States during the past five years, a new government study finds.

Typically, CA-MRSA causes boils, but it can lead to life-threatening conditions that are difficult to treat, according to the study.

The National Institute of Allergy and Infectious Diseases (NIAID) researchers said their findings resolve debate about the molecular evolution of CA-MRSA in the United States and rule out the possibility that multiple strains of USA300 emerged randomly with similar characteristics.

This single strain of USA300, which has spread with "extraordinary transmissibility" in the past five years, was identified by analyzing the genomes of USA300 collected from 10 patients infected in different parts of the United States between 2002 and 2005. Eight of the 10 samples had almost identical genomes, indicating they were from a common strain. The remaining two were related to the other eight, but more distantly.

The researchers also found that two of the eight almost identical USA300 samples caused far fewer deaths in laboratory mice than the other samples. This appears to support an emerging belief that tiny genetic changes among evolving strains have a major impact on disease severity and the potential for development of drug resistance.

The study was published in this week's online issue of the Proceedings of the National Academy of Sciences.

"The USA300 group of strains appears to have extraordinary transmissibility and fitness," research leader Frank R. DeLeo said in a prepared statement. "We anticipate that new USA300 derivatives will emerge within the next several years and that these strains will have a wide range of disease-causing potential."

It's hoped this research will lead to new test that can quickly identify specific MRSA strains.

A second study, led by the same NIAID scientists, discovered new information about how MRSA bacteria -- including the USA300 group -- avoid destruction by the human immune system's white blood cells. The study found that MRSA senses danger and turns the tables, killing the white blood cells.

That study was recently published online in The Journal of Immunology.

"Scientists are pressing ahead quickly to learn more about how some MRSA strains evade the immune system and spread quickly. The information presented in these two studies adds important new insights into that expanding knowledge base," NIAID Director Dr. Anthony S. Fauci said in a prepared statement.

More information

The U.S. Centers for Disease Control and Prevention has more about MRSA.



-- Robert Preidt



SOURCE: National Institute of Allergy and Infectious Diseases, news release, Jan. 21, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Computer-Related Eye Strain Not Just for Adults
2. Figure Skater Peggy Fleming, HealthSaver Says: Take Pains For Back Strains, 2nd Most Common Doctor Complaint
3. K-State Veterinary Lab Routinely Tests For Bluetongue Virus; Lab Director Says Strains Found in Kansas, U.S. Usually Less-Virulent
4. Chronic job strain doubles the risk of a second heart attack
5. High and mighty: first common height gene identified by researchers behind obesity gene finding
6. Lung Cancer Alliance Stands Behind CT Screening for Lung Cancer
7. The science behind the food we eat and the earth on which it grows
8. Plastic Surgery 2007: Where Truth Behind Emerging Cosmetic Treatments Meets Amazing Reconstructive Advances
9. Second pathway behind HIV-associated immune system dysfunction identified
10. Nationally Recognized Corporations and Retailers Rally Behind breastcancer.org
11. P&G Reports EPS of $0.92, Up 16% Behind 8% Sales Growth
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
One Strain Behind Epidemic of Staph Infections
(Date:5/27/2016)... ... 27, 2016 , ... More than a third of American adults are considered ... surgery has received increased attention in recent years, as an article published ... weight loss, most people are familiar with the basic requirements of maintaining a healthy ...
(Date:5/27/2016)... ... ... With over 60 percent of acute stroke survivors being left unable to ... in the rehabilitation process has steadily increased. Ekso Bionics had been working to help ... stroke. , Ekso Bionics has now received clearance from the U.S. Food and Drug ...
(Date:5/27/2016)... ... May 27, 2016 , ... Aimed ... by inspiring human interest stories, courtesy of leaders in the nursing and health ... the industry, from leading advocates and associations—namely Jones & Bartlett Learning. , Jones ...
(Date:5/26/2016)... ... ... There are many ways to cook a hot dog, but new research commissioned ... dogs straight off the grill. Of the 90 percent of Americans who say they ... hot dog, far outpacing other cooking methods such as steaming (12 percent), microwaving (9 ...
(Date:5/26/2016)... , ... May 26, 2016 , ... Connor Sports, ... basketball as a partner for the Tamika Catchings Legacy Tour that will ... industry leader in hardwood basketball surfaces in all forms and levels of the game, ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... MedDay, a biotechnology company focused on the treatment ... "High doses of biotin in progressive multiple sclerosis: extension phase ... Ayman Tourbah , Principal Investigator of the Phase 3 ... Neurology (EAN) in Copenhagen, Denmark . The ... on Sunday, 29 May 2016 from 14:45 to 16:15 CEST ...
(Date:5/24/2016)... --   , ... Endpunkte und demonstriert Ebenbürtigkeit bei der Gesamtreinigung des ... guter , Reinigung des ... (Logo: http://photos.prnewswire.com/prnh/20130829/633895-a ) , ... der MORA-Studie der Phase III für NER1006 (1 ...
(Date:5/24/2016)... Celsion Corporation (NASDAQ: CLSN ... an update on its ongoing OVATION study, a ... the Company,s DNA-based immunotherapy, with the standard of ... advanced ovarian cancer who will undergo neoadjuvant chemotherapy ... IL-12 DNA plasmid vector formulated as a nanoparticle ...
Breaking Medicine Technology: