Navigation Links
One Strain Behind Epidemic of Staph Infections
Date:1/21/2008

Government study found most MRSA infections in community linked to single evolving bacterium

MONDAY, Jan. 21 (HealthDay News) -- A single strain of an evolving bacterium has been responsible for most of the community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections that have spread rapidly in the United States during the past five years, a new government study finds.

Typically, CA-MRSA causes boils, but it can lead to life-threatening conditions that are difficult to treat, according to the study.

The National Institute of Allergy and Infectious Diseases (NIAID) researchers said their findings resolve debate about the molecular evolution of CA-MRSA in the United States and rule out the possibility that multiple strains of USA300 emerged randomly with similar characteristics.

This single strain of USA300, which has spread with "extraordinary transmissibility" in the past five years, was identified by analyzing the genomes of USA300 collected from 10 patients infected in different parts of the United States between 2002 and 2005. Eight of the 10 samples had almost identical genomes, indicating they were from a common strain. The remaining two were related to the other eight, but more distantly.

The researchers also found that two of the eight almost identical USA300 samples caused far fewer deaths in laboratory mice than the other samples. This appears to support an emerging belief that tiny genetic changes among evolving strains have a major impact on disease severity and the potential for development of drug resistance.

The study was published in this week's online issue of the Proceedings of the National Academy of Sciences.

"The USA300 group of strains appears to have extraordinary transmissibility and fitness," research leader Frank R. DeLeo said in a prepared statement. "We anticipate that new USA300 derivatives will emerge within the next several years and that these strains will have a wide range of disease-causing potential."

It's hoped this research will lead to new test that can quickly identify specific MRSA strains.

A second study, led by the same NIAID scientists, discovered new information about how MRSA bacteria -- including the USA300 group -- avoid destruction by the human immune system's white blood cells. The study found that MRSA senses danger and turns the tables, killing the white blood cells.

That study was recently published online in The Journal of Immunology.

"Scientists are pressing ahead quickly to learn more about how some MRSA strains evade the immune system and spread quickly. The information presented in these two studies adds important new insights into that expanding knowledge base," NIAID Director Dr. Anthony S. Fauci said in a prepared statement.

More information

The U.S. Centers for Disease Control and Prevention has more about MRSA.



-- Robert Preidt



SOURCE: National Institute of Allergy and Infectious Diseases, news release, Jan. 21, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Computer-Related Eye Strain Not Just for Adults
2. Figure Skater Peggy Fleming, HealthSaver Says: Take Pains For Back Strains, 2nd Most Common Doctor Complaint
3. K-State Veterinary Lab Routinely Tests For Bluetongue Virus; Lab Director Says Strains Found in Kansas, U.S. Usually Less-Virulent
4. Chronic job strain doubles the risk of a second heart attack
5. High and mighty: first common height gene identified by researchers behind obesity gene finding
6. Lung Cancer Alliance Stands Behind CT Screening for Lung Cancer
7. The science behind the food we eat and the earth on which it grows
8. Plastic Surgery 2007: Where Truth Behind Emerging Cosmetic Treatments Meets Amazing Reconstructive Advances
9. Second pathway behind HIV-associated immune system dysfunction identified
10. Nationally Recognized Corporations and Retailers Rally Behind breastcancer.org
11. P&G Reports EPS of $0.92, Up 16% Behind 8% Sales Growth
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
One Strain Behind Epidemic of Staph Infections
(Date:6/27/2016)... ... 27, 2016 , ... TherapySites, the leading website ... Tennessee Counseling Association. This new relationship allows TherapySites to continue to ... adding exclusive benefits and promotional offers. , "TCA is extremely excited about this ...
(Date:6/27/2016)... ... June 27, 2016 , ... A revolution ... the emergency ambulance transport experience for the millions of people who require these ... disrupted the taxi industry through the use of technology. Now, SmartEMS has put ...
(Date:6/26/2016)... PLAINSBORO, N.J. (PRWEB) , ... June 27, 2016 , ... ... same sources, yet in many ways they remain in the eye of the beholder, ... Oncology (EBO), a publication of The American Journal of Managed Care. For the full ...
(Date:6/26/2016)... ... June 26, 2016 , ... Pixel Film Studios Released ProSlice Levels, a ... can give their videos a whole new perspective by using the title layers ... Film Studios. , ProSlice Levels contains over 30 Different presets to choose from. ...
(Date:6/26/2016)... NC (PRWEB) , ... June 26, 2016 , ... Brent Kasmer, a legally blind and ... to be personalized through a fitness app. The fitness app plans to fix the two ... currently only offer a one size fits all type program , They don’t ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Mass. , June 24, 2016   ... Spaulding Rehabilitation Network,s Dean Center for Tick ... Physical Medicine and Rehabilitation, MIT Hacking Medicine, University ... for Innovation, today announced the five finalists of ... for Lyme disease.  More than 100 scientists, clinicians, ...
(Date:6/24/2016)... and SAN CLEMENTE, Calif. , June ... -based mobile pulmonary function testing company, is now able to ... devices developed by ndd Medical Technologies , Inc. ... done in hospital-based labs.  Thanks to ndd,s EasyOne PRO ® , ... , can get any needed testing done in the comfort of ...
(Date:6/24/2016)... , June 24, 2016  Arkis BioSciences, ... less invasive and more durable cerebrospinal fluid treatments, ... funding.  The Series-A funding is led by Innova ... Fund, and other private investors.  Arkis, new financing ... instrumentation and the market release of its in-licensed ...
Breaking Medicine Technology: