Navigation Links
One Shot May Someday Replace Six for Rabies
Date:9/23/2009

Experimental vaccine offers hope for millions of people worldwide, researchers say

WEDNESDAY, Sept. 23 (HealthDay News) -- An experimental rabies vaccine that may require only one injection produced promising results in animals, U.S. researchers report.

Currently, people exposed to rabies have to undergo six shots over 28 days -- five injections of the rabies vaccine and one injection of rabies immunoglobulin.

The new replication-deficient rabies virus vaccine lacks a key gene called the matrix (M) gene, according to a news release from Thomas Jefferson University, where the research was performed.

"The M gene is one of the central genes of the rabies virus, and its absence inhibits the virus from completing its life cycle. The virus in the vaccine infects cells and induces an immune response, but the virus is deficient in spreading," James McGettigan, an assistant professor of microbiology and immunology at Jefferson Medical College at the university in Philadelphia, said in the news release.

The immune response triggered by the vaccine is so strong that a single injection may be sufficient to protect a person who has been exposed to rabies, usually through being bitten by a rabid animal. The vaccine produced a rapid and efficient anti-rabies immune response in mice and non-human primates. The vaccine also appears to be efficient when used both before and after exposure to rabies, according to the research, which was published online Sept. 18 in the Journal of Infectious Diseases.

Worldwide, rabies kills between 40,000 and 70,000 people each year. Rabies is endemic in developing regions, where the six-shot anti-rabies regimen isn't feasible for many people due to cost and availability. Each year, about 10 million people undergo the post-exposure regimen, according to the World Health Organization.

"Developing countries do not have the resources to vaccinate people six times aft
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Patch Shots May Someday Replace Injections
2. Vaccine May Someday Thwart Ear Infections
3. UCF researchers nanoparticles could someday lead to end of chemotherapy
4. Alzheimers Drug May Someday Help Head Trauma Victims
5. Gene-Based Sunscreen Might Someday Prevent Skin Cancer
6. Advanced Alopecia Treatment developed by London-based Hair Replacement Provider
7. NorthShore University HealthSystem First in Illinois to Perform Remarkable Robotic Arm Guided Partial Knee Replacement Surgery
8. New Published Diet Study Reveals Meal Replacements as Top Strategy for Weight Loss
9. UK study finds meal replacements aid weight loss
10. New DrainEx(TM) Catheter Simplifies Insertion and Replacement
11. New DrainEx(TM) Catheter Simplifies Insertion and Replacement
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
One Shot May Someday Replace Six for Rabies 
(Date:12/20/2014)... 20, 2014 Parker & Sons, Inc. ... years of experience in contractor services announces reaching a ... for the homeowners of Arizona. Parker and Sons is ... contractor technicians that make customer service the number one ... Arizona and started with one service vehicle and has ...
(Date:12/19/2014)... (PRWEB) December 19, 2014 Sub Zero Ice ... sponsor a blood drive Sunday the 28th from 2pm-6pm at ... & Sawyer Road in Sarasota, FL. , Inquiries regarding time ... you for participating in the donating process, Sub Zero Ice ... flash frozen, custom ice cream. , About Sub Zero Ice ...
(Date:12/19/2014)... 2014 Eufaula, Oklahoma, located just 9 ... the state’s largest lake with more than 600 miles ... to a little more than 3,000 residents, hosted its ... the 6th of December. , Featuring Santa, Christmas lights ... Eufaula on Main Street. Narconon Arrowhead’s parade float ...
(Date:12/19/2014)... warns parents that buying an older car for their teens may ... drivers killed in the United States between 2008 and 2012 were ... lacked important safety features that are available on newer cars, the ... were in cars at least six years old, 34 percent were ... cars 11 to 15 years old, and 17 percent were in ...
(Date:12/19/2014)... 2014 (HealthDay News) -- Dense bunches of bacteria called biofilms ... new study finds. The researchers said these biofilms ... The presence of these biofilms may represent an increased ... to predict a person,s risk for the disease, the researchers ... these biofilms may coat the mucus layer of cells lining ...
Breaking Medicine News(10 mins):Health News:Parker & Sons Announces Reaching A Milestone By Providing 40 Years Of Dedicated Contractor Services For Homeowners Of Arizona 2Health News:Parker & Sons Announces Reaching A Milestone By Providing 40 Years Of Dedicated Contractor Services For Homeowners Of Arizona 3Health News:Shark Tank’s Sub Zero Ice Cream Sponsors Blood Drive 2Health News:Narconon Arrowhead Debuts Float at Checotah and Eufaula Christmas Parades 2Health News:Narconon Arrowhead Debuts Float at Checotah and Eufaula Christmas Parades 3Health News:Older Cars a Bad Choice for Younger Drivers 2Health News:Could Bacteria Play a Role in Colon Cancer? 2
... A majority of Floridians (87%) believe it is important for ... research, according to a new state poll commissioned by Research!America. ... scientific research is important for Florida,s economy in terms of ... believe the state should lead in science and technology education ...
... Are children suffering needlessly after surgery? UC Irvine ... An operation can be one of the most traumatic ... many of them experience unnecessary postsurgical pain lasting weeks ... and treated in adults but has been generally overlooked ...
... have determined that master transcription factors determine the genes ... pathways are targeted to genes that are most relevant ... control cell state, growth, differentiation, and death. ... cell receives instructions from its neighbors and the environment ...
... of the things that makes inhalational anthrax so worrisome for ... inhaled anthrax spores can turn into a lethal infection. By ... something worse than the flu and seeks treatment, it,s often ... help against the spreading bacteria and the potent toxins they ...
... and early adulthood takes its toll on the body, and ... and women, irrespective of how tough things have been in ... University in Sweden and colleagues, experience of social and material ... to a rise in disease risk factors in middle age, ...
... -- The mere presence of a predator causes enough stress ... get at its prey to eat it, say biologists at ... fear of being eaten is an important topic in ecology, ... affect predator and prey interactions," says Professor Locke Rowe, chair ...
Cached Medicine News:Health News:Florida poll: Research important for state economy, jobs 2Health News:Florida poll: Research important for state economy, jobs 3Health News:How major signaling pathways are wired to our genome gives new insight into disease processes 2Health News:How major signaling pathways are wired to our genome gives new insight into disease processes 3Health News:Natural killer cells could be key to anthrax defense 2Health News:Hard times during adolescence point to health problems later in life 2Health News:Insects are scared to death of fish 2
(Date:12/17/2014)... , The new ... of information concerning the biopharmaceutical Group,s national and international clinical ... to the recently launched institutional website that is receiving accolades ... by a new chapter in the fascinating story of Drug ... and panoramic hub on the world of clinical research, ranging ...
(Date:12/17/2014)... Mass. , Dec. 17, 2014  RXi ... biotechnology company focused on discovering, developing and commercializing ... RNA-targeted technologies, today announced completion of enrollment in its ... from the 3-month observations confirmed the 1-month findings ... Logo - http://photos.prnewswire.com/prnh/20130917/NE80755LOGO ...
(Date:12/15/2014)... , December 15, 2014 ... Am 19. und 20. Februar sind alle ... SAFE MEDICINE ECOSYSTEM PARTNER PROGRAMM ™ 2015 ... besuchen. Diese Tagung soll dazu ... Möglichkeit geben, die neue profitablen Unternehmensdienstleistungen, die ...
Breaking Medicine Technology:Dompé Offers a New "Window" on the World of Scientific Research, with the http://www.dompetrials.com Website, Dedicated to Clinical Trials 2Dompé Offers a New "Window" on the World of Scientific Research, with the http://www.dompetrials.com Website, Dedicated to Clinical Trials 3RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301 2RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301 3RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301 4RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301 5Symposium über Aegates Ecosystem-Partner-Programm für sichere Medikamente vom 19. - 20. Februar 2015 in Amsterdam 2
The cemented hip joint prosthesis system....
The uncemented hip joint prosthesis system....
The cemented hip joint prosthesis system....
The Quatroloc primary hip system offers 35 primary stems to fit almost all femurs for primary hip arthroplasty....
Medicine Products: