Navigation Links
One Shot May Someday Replace Six for Rabies
Date:9/23/2009

Experimental vaccine offers hope for millions of people worldwide, researchers say

WEDNESDAY, Sept. 23 (HealthDay News) -- An experimental rabies vaccine that may require only one injection produced promising results in animals, U.S. researchers report.

Currently, people exposed to rabies have to undergo six shots over 28 days -- five injections of the rabies vaccine and one injection of rabies immunoglobulin.

The new replication-deficient rabies virus vaccine lacks a key gene called the matrix (M) gene, according to a news release from Thomas Jefferson University, where the research was performed.

"The M gene is one of the central genes of the rabies virus, and its absence inhibits the virus from completing its life cycle. The virus in the vaccine infects cells and induces an immune response, but the virus is deficient in spreading," James McGettigan, an assistant professor of microbiology and immunology at Jefferson Medical College at the university in Philadelphia, said in the news release.

The immune response triggered by the vaccine is so strong that a single injection may be sufficient to protect a person who has been exposed to rabies, usually through being bitten by a rabid animal. The vaccine produced a rapid and efficient anti-rabies immune response in mice and non-human primates. The vaccine also appears to be efficient when used both before and after exposure to rabies, according to the research, which was published online Sept. 18 in the Journal of Infectious Diseases.

Worldwide, rabies kills between 40,000 and 70,000 people each year. Rabies is endemic in developing regions, where the six-shot anti-rabies regimen isn't feasible for many people due to cost and availability. Each year, about 10 million people undergo the post-exposure regimen, according to the World Health Organization.

"Developing countries do not have the resources to vaccinate people six times aft
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Patch Shots May Someday Replace Injections
2. Vaccine May Someday Thwart Ear Infections
3. UCF researchers nanoparticles could someday lead to end of chemotherapy
4. Alzheimers Drug May Someday Help Head Trauma Victims
5. Gene-Based Sunscreen Might Someday Prevent Skin Cancer
6. Advanced Alopecia Treatment developed by London-based Hair Replacement Provider
7. NorthShore University HealthSystem First in Illinois to Perform Remarkable Robotic Arm Guided Partial Knee Replacement Surgery
8. New Published Diet Study Reveals Meal Replacements as Top Strategy for Weight Loss
9. UK study finds meal replacements aid weight loss
10. New DrainEx(TM) Catheter Simplifies Insertion and Replacement
11. New DrainEx(TM) Catheter Simplifies Insertion and Replacement
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
One Shot May Someday Replace Six for Rabies 
(Date:1/22/2015)... 2015 Yesterday, Senator Holly Mitchell ... Kristin Olsen (R-Modesto) were honored by the California ... biotechnology, biomedical science, medical device and pharmaceutical innovation ... the “2014 Life Sciences Champion” award from CHI ...
(Date:1/22/2015)... Florida (PRWEB) January 22, 2015 IsoComforter, Inc. ... therapy machine with patented IsoTube design to treat specific body ... introduced the most progressive and easy to use patented cold ... post-operative and sports related orthopedic and muscle injuries. IsoComforter ...
(Date:1/22/2015)... WASHINGTON, DC (PRWEB) January 22, 2015 ... conditions in vulnerable communities and cause financial distress to ... report by analysts at Howard University’s Center on Race ... of dollars in economic activity, payday loans at the ...
(Date:1/22/2015)... 22, 2015 As interest in the value ... gains momentum worldwide, Rev. Eric J. Hall , president ... (HCCN), will be the keynote speaker on January 27 ... public health system. , The conference, “Hope and Resilience: Innovative ...
(Date:1/22/2015)... 22, 2015 Compare-autoinsurance.org has released a new blog ... an auto insurance policy . , Some types of ... should check the newly released blog post to see if their ... dangerously damaged vehicles are some of the cars that cannot be ...
Breaking Medicine News(10 mins):Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 3Health News:IsoComforter Introduces Best of Class Cold Therapy Product to the Worldwide Market 2Health News:Howard University Spotlights the Economic Impact of Payday Lending in Southern States 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 3Health News:Some Vehicles Cannot Be Covered By An Auto Insurance Policy! 2
... to be an effective anti-depressant is also found to ... sure about the mechanism of serotonin inhibitors on human ... and team from Georgetown University Medical center have found ... found to be an effective antidepressant by passing ...
... ambulance service will be established in the Indian city of ... providing patients with critical help.// The project is estimated at ... Hinduja Hospital. The annual recurring cost of the project will ... four medical colleges will initially be a part of the ...
... report has unraveled how the neurons located in different areas ... human eye visualizes, be it a letter, number or some ... and is fitted together like a puzzle to help in ... (funded by the National Institutes of Health) appear in the ...
... of the men in the US suffer from erectile dysfunction ... heart diseases. // The number of visits to doctors rose ... 1998. The data available from the National Health and Nutrition ... his colleagues. ,About 2,126 men aged over 20 ...
... Cleveland Clinic, is a very reputed hospital in the US ... 2006. // ,The online service extends the Clinic's ... East. Middle-East has many a number of excellent doctors but ... opinion. ,To avoid this situation the Cleveland Clinic ...
... drug plan came in to effect on Jan 1st, but ... trouble dealing with the issue//. ,The plan has ... of Medicare came to know about it when they received ... was very difficult to understand which prescription drug services from ...
Cached Medicine News:Health News:Mumbai To Get Emergency Ambulance Service 2Health News:Visualization Found To Be Largely Dependent On The Brain 2Health News:The Cleveland Clinic Expands Its Services across the World via the Net 2Health News:Bush’s new prescription drug plan, a complex puzzle for the citizen 2
(Date:1/23/2015)... , Jan. 23, 2015  Pete Rose, baseball,s all-time hits leader, ... arthritis pain reliever Myoflex, Ducere Pharma has announced. ... are excited to have him on board with Myoflex," said ... is a legendary player who is known across all generations. ...
(Date:1/23/2015)... , Jan. 23, 2015  iMD Companies, Inc. (ICBU) has ... increase market share and grab a foothold in the hydroponic, ... production capabilities and a presence in the sector, and recently ... the growth of hemp and medical marijuana, iMD is committing ...
(Date:1/23/2015)... Africa , Jan. 23, 2015   Leatt Corporation ... personal protective equipment for all forms of sports, including ... Leatt-Brace® neck brace, announced today that the UISP Lega ... now requires all riders to wear a neck brace ...
Breaking Medicine Technology:Pete Rose bets on Myoflex to relieve aches and pains 2iMD Companies Poised to Make Impact in Multi-Billion Dollar Medical Marijuana Sector With Recent Investments and Strategic Partnerships 2Leatt Announces Neck Braces Now Required For Motocross/Minicross Racing In Italy 2Leatt Announces Neck Braces Now Required For Motocross/Minicross Racing In Italy 3
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: