Navigation Links
Onconova to present clinical trials update on ON 01910.Na at American Society of Hematology Meeting
Date:12/3/2010

NEWTOWN, PA and PRINCETON, NJ Dec. 3, 2010 / PRNewswire-FirstCall / Onconova Therapeutics announces its late-stage anticancer agent, Estybon (ON 01910.Na), will be featured in three presentations at the 52nd American Society of Hematology (ASH) Annual Meeting in Orlando, FL, December 4-7, 2010.

Principal investigators at four centers, Dr. Lewis Silverman (Mount Sinai Medical Center), Dr. Azra Raza (Columbia University Medical Center), Dr. Elaine Sloand (NHLBI), and Dr. Peter Greenberg (Stanford University Medical Center) report that in 48 higher risk patients with MDS or AML (who failed or became resistant to previous drug treatments), when treated with ON 01910.Na showed increases in overall survival, which correlated with bone marrow blast responses. The most dramatic improvement in overall survival was seen in 19 patients who also showed either bone marrow complete response (CR) or initial >50% decrease in blast cells (Abstract #3998). Dr. Greenberg's team reports encouraging efficacy and drug tolerance results in a Phase II trial with patients who had all failed the standard hypomethylating agent treatments (Abstract #4010). Dr. Silverman and colleagues have observed 50% responders in a Phase I study (Abstract #2944).

Estybon (ON 01910.Na) is a small molecule, targeted therapeutic with a broad spectrum of activity. It has been tested in patients with solid tumors, myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) at major centers in the U.S. and abroad. MDS and AML are blood disorders widely recognized as difficult to manage, with limited therapeutic options for patients, especially those with drug-resistant disease. The presentations will describe the latest results on activity and safety of Estybon (ON 01910.Na) in MDS and AML patients treated in on-going Phase I and Phase II clinical trials.

These studies are a part of comprehensive evaluation of the safety and activity of Estybon (ON 01910.Na). To
'/>"/>

Contact: Kathryn Morris
kathryn@proncall.com
845-635-9828
PR on Call
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Onconova Therapeutics presents new data demonstrating radioprotection by Ex-RAD at RRS annual meeting
2. Connor Sport Court Lays the Ground for NBA All-Star Jam Session Presented by Adidas
3. FAB-HOMES™ Presents First Passive House Collection
4. Researchers Who Discovered First Genes for Stuttering will Present Findings to the National Stuttering Association
5. Digital Signatures Presented at Electronic Document Management Conference
6. Compex , Leaders in Electronic Muscle Stimulators, Sponsors the Jelly Belly Cycling Team Presented by Kenda
7. Game Ready(R) Presented with Frost & Sullivan 2010 Product Differentiation Excellence Award
8. Great Salt Lake Chapter of National Contract Management Association Hosts Presentation on False Claims Act by Qui Tam Attorney Tim Terry
9. NOVAVAX Presents Positive Clinical Results at The World Health Organization Conference, Geneva, Switzerland
10. AADR presents honorary membership to Senator Tom Harkin
11. WebMD to Present at the Goldman Sachs Technology and Internet Conference 2010
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... Women’s health specialist, Dr. Amber Murphy, MD, Ob/Gyn ... Inc., A Division of MaternOhio Clinical Associates, Inc., who ... patients annually. Dr. Murphy will provide a full range ... women’s life. She is accepting new patients at two ... , Dr. Murphy offers a wide variety of services ...
(Date:10/20/2014)... 2014 JZ Fitness, an independently operated ... wellness programming, authorship, international lecturing and community wellness, created ... the release of the JZ Fitness nutrition app, available ... coaching thousands of individuals on nutrition, Jenn Zerling (“JZ”) ... not require calorie counting or cumbersome food logging. ...
(Date:10/20/2014)... PA (PRWEB) October 20, 2014 ... Matthew Voicheck as Assistant Director of their ... role in managing the innovative turnkey drug sourcing, ... , Matthew brings over 12 years of industry ... joins Myoderm at the peak of their international ...
(Date:10/20/2014)... 20, 2014 National Teen Driver Safety Week ... American Academy of Pediatrics (Ohio AAP, http://www.ohioaap.org ) is ... parents of teen drivers to talk to their teens and ... Motor vehicle crashes are the leading cause of death for ... in fatal crashes, and 859 (42%) of those teen drivers ...
(Date:10/20/2014)... New York, NY (PRWEB) October 20, 2014 ... to be introduced in the U.S., has a lot to ... time when our country recognizes the achievements and contributions of ... marks the anniversary for Punzoné, and today it shares its ... and take a trip to Italy - even if it ...
Breaking Medicine News(10 mins):Health News:OhioHealth Welcomes New Women’s Health Specialist to MaternOhio Specialists in Obstetrics & Gynecology of Columbus, Inc. 2Health News:OhioHealth Welcomes New Women’s Health Specialist to MaternOhio Specialists in Obstetrics & Gynecology of Columbus, Inc. 3Health News:JZ Fitness Nutrition App Launches on iTunes 2Health News:JZ Fitness Nutrition App Launches on iTunes 3Health News:Myoderm Hires Matthew Voicheck to Lead Turnkey Drug Sourcing Service 2Health News:Ohio AAP Promotes National Teen Driver Safety Week 2Health News:Celebrate Italian Heritage Month With Authentic Cocktails from Punzoné: The Only Ultra Premium Line of Organic Imported Italian Vodka 2Health News:Celebrate Italian Heritage Month With Authentic Cocktails from Punzoné: The Only Ultra Premium Line of Organic Imported Italian Vodka 3Health News:Celebrate Italian Heritage Month With Authentic Cocktails from Punzoné: The Only Ultra Premium Line of Organic Imported Italian Vodka 4
... rate since 1999, WASHINGTON, Sept. 11 ... eight years, marking the fourth,consecutive year premium increases ... Published by the Kaiser Family Foundation and ... 2007 Annual Survey found,that health insurance premiums increased ...
... Sept. 11 GlaxoSmithKline (NYSE:,GSK) believes that conclusions ... Nissen et. al. and Furberg et. al. in ... not confirm a difference in the,safety profile of ... that are common to all meta-analyses, by,the authors, ...
... Local Business Community Comes Together in Support of Event, ... still available for the fourth annual Detroit Uncorked, one ... Center, is held at Ford Field, Sept. 28 from ... Motor Company and Ford Field and created and,organized by ...
... Pennsylvania with substantial experience in infection control ... The Pennsylvania,Patient Safety Authority,s Board of Directors ... to help implement Act 52 of 2007. The,act ... in July to help reduce and,eliminate healthcare-associated infections ...
... Journal of the America Heart Association confirms that when young ... influence their heart disease risk later in life. ... have landmark implications on how children should be taught to ... reduction in intake of saturated fat, was found to be ...
... 11 (HealthDay News) -- Carvedilol, a newer member of the beta ... failure, did not help children with the condition, a new study ... it -- was almost exactly the same for 103 young heart-failure ... got a placebo. , "Heart failure in children is both not ...
Cached Medicine News:Health News:Health Insurance Premium Growth Slows for Fourth Straight Year 2Health News:GlaxoSmithKline Responds to JAMA Articles 2Health News:GlaxoSmithKline Responds to JAMA Articles 3Health News:GlaxoSmithKline Responds to JAMA Articles 4Health News:GlaxoSmithKline Responds to JAMA Articles 5Health News:Tickets Still Available for Detroit Uncorked; 2Health News:Patient Safety Authority Board of Directors Names Infection Advisory Panel 2Health News:Patient Safety Authority Board of Directors Names Infection Advisory Panel 3Health News:Patient Safety Authority Board of Directors Names Infection Advisory Panel 4Health News:Patient Safety Authority Board of Directors Names Infection Advisory Panel 5Health News:Patient Safety Authority Board of Directors Names Infection Advisory Panel 6Health News:Patient Safety Authority Board of Directors Names Infection Advisory Panel 7Health News:Patient Safety Authority Board of Directors Names Infection Advisory Panel 8Health News:Patient Safety Authority Board of Directors Names Infection Advisory Panel 9Health News:Children who learn heart healthy eating habits lower heart disease risk 2Health News:Children who learn heart healthy eating habits lower heart disease risk 3Health News:Beta Blocker Doesn't Help Children With Heart Failure 2
(Date:10/17/2014)... October 17, 2014 ... has announced the addition of the  "China ... their offering.       (Logo: http://photos.prnewswire.com/prnh/20130307/600769) ... in China impacted ... in consumption concept, dietary habit, way of ...
(Date:10/17/2014)... 17, 2014 Investor-Edge has initiated ... ARNA ), NPS Pharmaceuticals Inc. (NASDAQ: ... ), Momenta Pharmaceuticals Inc. (NASDAQ: MNTA ), ... on these five companies can be accessed at: ... October 16, 2014, ended on a mixed note as ...
(Date:10/17/2014)... BALTIMORE , Oct. 17, 2014  Ameritox SM ... announced the appointment of Thomas Smith , M.D., ... lead a field-based team offering scientific resources for healthcare ... Smith has held leadership positions at a variety of ... will benefit both the pain and behavioral health sides ...
Breaking Medicine Technology:China Interventional Cardiovascular Device Industry Report 2014-2017 2China Interventional Cardiovascular Device Industry Report 2014-2017 3Biotech Equities Technical Briefing - Arena Pharma, NPS Pharma, XOMA, Momenta Pharma, and Catalyst Pharma Partners 2Biotech Equities Technical Briefing - Arena Pharma, NPS Pharma, XOMA, Momenta Pharma, and Catalyst Pharma Partners 3Biotech Equities Technical Briefing - Arena Pharma, NPS Pharma, XOMA, Momenta Pharma, and Catalyst Pharma Partners 4Biotech Equities Technical Briefing - Arena Pharma, NPS Pharma, XOMA, Momenta Pharma, and Catalyst Pharma Partners 5Ameritox Appoints New Chief Medical Officer 2
... Pharmaceuticals, Inc. announced the appointment of Dave Lemus as ... 2011.  Lemus will join the leadership team at Sigma-Tau ... For the past 13 years, Lemus served as chief ... Segment; TecDAX), one of the Europe,s leading biotechnology companies ...
... Pharmaceuticals, Inc. (NASDAQ: AVNR ) today announced ... indicates that an Abbreviated New Drug Application (ANDA) for ... sulfate) capsules was submitted on March 7, 2011. The ... 2011. Avanir intends to vigorously enforce its ...
Cached Medicine Technology:Sigma-Tau Pharmaceuticals, Inc. Announces Addition of VP of Finance 2Avanir Pharmaceuticals Announces Paragraph IV ANDA Filing for NUEDEXTA 2Avanir Pharmaceuticals Announces Paragraph IV ANDA Filing for NUEDEXTA 3Avanir Pharmaceuticals Announces Paragraph IV ANDA Filing for NUEDEXTA 4
The PICO50 is used for arterial line sampling....
The safePICO is a prebarcoded arterial sampler that helps you ensure patient and caregiver safety. SafePICO is part of 1st automatic, the worlds first automatic blood gas analysis system....
Non-invasive and continuous tcpCO2 and tcpO2 patient monitoring....
The TCM400 is the first and only portable instrument to provide up to six simultaneous measurements of transcutaneous oxygen tension (tcpO2)...
Medicine Products: