Navigation Links
Once-Daily Combo Works for New HIV Patients
Date:8/2/2008

Tazanavir/ritonavir as good as twice-daily dose of lopinavir/ritonavir, study says

FRIDAY, Aug. 1 (HealthDay News) -- Once-daily treatment with tazanavir/ritonavir (A/R) is as effective as twice-daily treatment with lopinavir/ritonavir (L/R) in HIV patients who are starting antiretroviral treatment for the first time, a European study shows.

Based on their findings, the researchers recommended once-daily A/R as a first-line treatment option for treatment-naive HIV patients since it has a number of advantages over the currently recommended twice-daily L/R.

The study included 883 treatment-naive HIV patients who were randomly assigned to receive A/R 300/100 milligrams once daily (440 patients) or L/R 400/100 milligrams twice daily (443 patients). Both regimens were in combination with tenofovir/emtricitabine 300/200 once daily, as is standard.

After 48 weeks of treatment, 78 percent of patients receiving A/R and 76 percent of those receiving L/R had a viral load of less than 50 copies per milliliters in their blood, and both groups showed similar increases in the numbers of immune system CD4 cells. Six percent of patients in both groups failed on the treatments, and two patients in the A/R group developed resistance mutations to treatment, compared with none in the L/R group.

Serious side effects were reported in 12 percent of the A/R patients and 10 percent of the L/R patients, but fewer A/R patients experienced treatment-related diarrhea (2 percent vs. 11 percent) and nausea (4 percent vs. 8 percent). None of the L/R patients developed jaundice, which occurred in 4 percent of A/R patients.

"In treatment-naive patients, atazanavir/ritonavir once-daily demonstrated similar antiviral efficacy to lopinavir/ritonavir twice daily, with less gastrointestinal toxicity but with a higher rate of hyperbilirubinaemia...the results of this study support the use of once-daily atazanavir/ritonavir as a recom
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Labopharms Once-Daily Tramadol Product Launched in South Korea, Australia, Romania and Austria
2. New Data Highlights Positive Results of Namenda (Memantine HCl) Once-Daily Extended-Release Formulation
3. FDA accepts Labopharms response for once-daily tramadol as complete Class 2 response
4. Labopharm Reaquires UK Sales And Marketing Rights to Its Once-Daily Tramadol Product
5. Labopharm Submits Complete Response to FDA as a Result of Outcome of Appeal Process for Once-Daily Tramadol
6. Labopharm Receives Response from FDA Regarding its Once-Daily Tramadol Product
7. FDA approves VYVANSE, first and only once-daily prodrug stimulant to treat ADHD in adults
8. Labopharm Appeals FDAs Decision on Once-Daily Tramadol to Next Supervisory Level After Additional Analysis Supports Efficacy
9. Once-Daily Insulin Shot Proves Effective in Study
10. A Once-Daily Oral Drug for Chronic Obstructive Pulmonary Disease That Treats COPD-Related Inflammation Could Achieve Blockbuster Status
11. Labopharms Once-Daily Tramadol Approved in South Korea and Australia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/6/2015)... (PRWEB) May 06, 2015 Corporate ... behalf of MEBC, an Alliance Award for excellence ... during FOCUS 2015, JDA’s annual user conference which ... retail and wholesale distribution sectors. This award recognizes ... are receiving services that advance their supply chain ...
(Date:5/6/2015)... Baptist Medical Center Jacksonville and ... north Florida and southeast Georgia region offering MAKOplasty® ... in total hip replacement surgery performed using the ... that enables the accurate alignment and positioning of ... MAKOplasty® partial knee resurfacing using the RIO system ...
(Date:5/6/2015)... 06, 2015 “ SideChef ” was featured on ... at the latest and coolest applications on the market for iOS, ... expert, conducted the app review and shared with viewers how this ... day when to be a good navigator people had to know ... now everyone is a master navigator. Well what if people could ...
(Date:5/6/2015)... 06, 2015 Anitha Nallari, MD ... Oncology Consultants, Inc. in Columbus, OH. Dr. Nallari will ... special focus in breast cancer, lung cancer, GI and gallbladder ... well as benign hematology. , Dr. Anitha Nallari ... by the American Board of Internal Medicine. She completed her ...
(Date:5/6/2015)... Follow us on LinkedIn ... by the rising consumer awareness over the importance of ... Hand washing is becoming a part of personal hygiene ... infections. Periodic outbreak of Avian flu, Swine flu, and ... disease (EVD) epidemic in West Africa are mega ...
Breaking Medicine News(10 mins):Health News:MEBC Receives Award for Consulting Excellence in Retail 2Health News:Baptist Health and Jacksonville Orthopaedic Institute Offering MAKOplasty® Total Hip Replacement 2Health News:Baptist Health and Jacksonville Orthopaedic Institute Offering MAKOplasty® Total Hip Replacement 3Health News:Baptist Health and Jacksonville Orthopaedic Institute Offering MAKOplasty® Total Hip Replacement 4Health News:An Application to Guide Users through Recipes Was Featured on NewsWatch Television 2Health News:New Oncologist to Join Hematology Oncology Consultants, Inc. 2Health News:New Oncologist to Join Hematology Oncology Consultants, Inc. 3Health News:Growing Apprehension Amid Disease Outbreaks Drives Global Sales of Hand Sanitizers, According to a New Report by Global Industry Analysts, Inc. 2Health News:Growing Apprehension Amid Disease Outbreaks Drives Global Sales of Hand Sanitizers, According to a New Report by Global Industry Analysts, Inc. 3Health News:Growing Apprehension Amid Disease Outbreaks Drives Global Sales of Hand Sanitizers, According to a New Report by Global Industry Analysts, Inc. 4
... to reduce the problems caused by pollen , SATURDAY, ... many allergy sufferers, will soon be in bloom. , ... nose, sore throat, congestion and problems sleeping for the ... the American Academy of Allergy, Asthma & Immunology (AAAAI). ...
... ... spreading, one of the best protections may actually be right under our nose. FDNSC, ... adding another much needed layer of prevention against the flu viruses. , ... Tampa, FL (PRWEB) August 29, 2009 -- As ...
... infected with type D were affected, study found , ... HIV a person has may determine their odds for ... Cognitive difficulties, even dementia, are a common hallmark of ... led by Dr. Ned Sacktor noted that people in ...
... New White Paper Reveals the Proposed Rationing of Quality Hospital ... Today, the Senior Center for Health and Security (SCHS) announced ... the critical nature of high-quality physician hospitals for seniors, their promise ... completely out of existence. , , "According to ...
... PITTSBURGH, Aug. 28 Children,s Hospital of Pittsburgh ... research organization, as the leader in its use of healthcare ... , KLAS interviewed leaders at virtually every ... actively using commercially available software to order and chart under ...
... , CINCINNATI, Aug. 28 Dr. Will ... that the American public is NOT getting adequate information on how ... Flu (Swine Flu)! Sawyer,s advice includes, crucially, "Do NOT Touch ... contamination (inoculation) of mucus membranes, which are the portal of entry ...
Cached Medicine News:Health News:Get Ready for Ragweed 2Health News:First Defense Nasal Screen Comp. Releases New Protection Product Just in Time for Pandemic Flu Season 2Health News:First Defense Nasal Screen Comp. Releases New Protection Product Just in Time for Pandemic Flu Season 3Health News:First Defense Nasal Screen Comp. Releases New Protection Product Just in Time for Pandemic Flu Season 4Health News:America Needs More Physician Hospitals 2Health News:Children's Hospital of Pittsburgh of UPMC Recognized for Deepest Use of Electronic Health Records for a Pediatric Hospital in Nation 2Health News:Children's Hospital of Pittsburgh of UPMC Recognized for Deepest Use of Electronic Health Records for a Pediatric Hospital in Nation 3Health News:Solution to PREVENT Novel H1N1 (Swine Flu) From Closing Down Schools! 2
(Date:5/6/2015)... , May 6, 2015 The Parenteral Drug ... has finalized agreement with Richard M. Johnson ... "We are very pleased to have Richard ... Hal Baseman , the Chair of the Board ... performance and growth.  Richard has led a strong staff ...
(Date:5/6/2015)... PARIS , May 6, 2015 ... the development and manufacture of filtration products, mainly for ... ZenPure designs custom filters manufactured in a state-of-the-art plant ... are marketed and sold across the globe and will ... Plastics business. This acquisition is fully in ...
(Date:5/6/2015)... DUBLIN , May 06, 2015 Research ... announced the addition of the "Global Suture ... The Global Suture Industry Report 2015 ... current state of the suture industry. ... industry including definitions, classifications, applications and industry chain ...
Breaking Medicine Technology:PDA Extends Richard M. Johnson as President/CEO for Six Additional Years 2Saint-Gobain Acquires ZenPure, a Specialist in Filtration Products 2Global Suture Industry Report 2015 - Forecast Trends to 2021 2Global Suture Industry Report 2015 - Forecast Trends to 2021 3
... effort to meet industry demands for expanded Cephalosporin ... administration, B. Braun Medical Inc. (B. Braun) announced ... USP and Dextrose Injection USP in B. ... will be available for purchase beginning today. ...
... NXTM ), a leading manufacturer of innovative dialysis ... the third quarter ended September 30, 2010 on Thursday, November ... NxStage will also host a conference call at 9:00 ... its third quarter financial results. To listen to the conference ...
Cached Medicine Technology:FDA-Approved Cefepime Now Available for Use in B. Braun's DUPLEX® System 2NxStage to Report Third Quarter Fiscal 2010 Financial Results 2
... Neonatal and Pediatric TRACH ... for intubated patients. Rounded ... provide smooth surface interface. ... locking thumb port. Multiple ...
... spiral reinforced. X-ray opaque. Super safety low ... use. Adjustable Flange: The flange can be ... the thickness of the cervical soft tissue. ... the flange is tightly connected to the ...
... patients with obstructive sleep apnea necessitating tracheotomy, ... support. Also indicated where airway access for ... ,Another excellent choice for a sleep ... tube series. Available with a low profile ...
... patient safety, the laryngectomy tube ... 15 mm ISO termination that ... ventilator, with or without the ... ,Portex® laryngectomy tubes are ...
Medicine Products: