COLUMBUS, Ohio A new study gauging the impact of consuming more fish oil showed a marked reduction both in inflammation and, surprisingly, in anxiety among a cohort of healthy young people.
The findings suggest that if young participants can get such improvements from specific dietary supplements, then the elderly and people at high risk for certain diseases might benefit even more.
The findings by a team of researchers at Ohio State University were just published in the journal Brain, Behavior and Immunity. It is the latest from more than three decades of research into links between psychological stress and immunity.
Omega-3 polyunsaturated fatty acids, such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have long been considered as positive additives to the diet. Earlier research suggested that the compounds might play a role in reducing the level of cytokines in the body, compounds that promote inflammation, and perhaps even reduce depression.
Psychological stress has repeatedly been shown to increase cytokine production so the researchers wondered if increasing omega-3 might mitigate that process, reducing inflammation.
To test their theory, they turned to a familiar group of research subjects medical students. Some of the earliest work these scientists did showed that stress from important medical school tests lowered students' immune status.
"We hypothesized that giving some students omega-3 supplements would decrease their production of proinflammatory cytokines, compared to other students who only received a placebo," explained Janice Kiecolt-Glaser, professor of psychology and psychiatry.
"We thought the omega-3 would reduce the stress-induced increase in cytokines that normally arose from nervousness over the tests."
The team assembled a field of 68 first- and second-year medical students who volunteered for the clinical trial. The students were randomly
|Contact: Janice Kiecolt-Glaser|
Ohio State University