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Omega-3 EPA: Treatment for a Heart Condition
Date:6/11/2009

properties of fish oil. If there was anything out there that could strengthen her heart and help her to avoid a heart operation in future, I was going to find it," said Dr Nazemi.

"My wife, Anne, had always been very clued up about complementary treatments, and with her scrupulous ability to research the internet we began a long process which, unusually, ended up with the discovery that there wasn't anything on the market that was quite what our daughter needed. We decided there and then that we would invest what we could into creating the supplement which would help Roxana, and indeed many others too."

During this time, Dr Puri's research evolved and it wasn't long before he was extolling the virtues of an active component within fish oil, a specific omega-3 fatty acid called EPA (eicosapentaenoic acid). Although another fatty acid in fish oil - DHA (docosahexaenoic acid) - is also known to be essential for health in its natural form in food, studies were showing that when combined in concentrated supplement form it was inhibiting the beneficial effects of EPA. Dr Puri, now Professor, and Head of the Lipid Neuroscience Department at Hammersmith Hospital, was and is still adamant that as the ratio of EPA to DHA in a supplement rises, so does its efficacy. "It was clear that EPA in its pure form, extracted from fish oil, would have to be sourced, in order to maximise the benefits," Jav added.

Further research refined the formulation, since the body requires a precise ratio of omega-3 and omega-6 fatty acids. Generally, it is thought that we now have too many omega-6s (particularly from vegetable oils and red meat) in the Western diet and that the balance has shifted too far in favour of the omega-6 pathway. Scientists suggest that this shift is responsible for many problems, especially excess inflammation in the body. One specific type of omega-6, however, has potent anti-inflammatory properties, namely GLA (gamma
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