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Oldest Heart Patients May Get Most From Warfarin
Date:8/31/2009

the reduction in ischemic stroke attributable to treatment against the increase in intracranial bleeding associated with the drug. Since intracranial hemorrhages usually have worse outcomes than ischemic strokes, bleeding events were given greater weight in the comparison.

While warfarin therapy benefited most atrial fibrillation patients, the balance of benefits over risks was greatest in those at highest risk of stroke -- those with multiple risk factors, those with a history of stroke and the oldest patients. Benefits of treatment increased with age, with no clear value seen in patients younger than 65. However, a reduction of more than two strokes per 100 patients was seen in people 85 and older.

More information

The American Heart Association has more on atrial fibrillation here.



SOURCE: Massachusetts General Hospital, news release, Aug. 31, 2009


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