Navigation Links
Older age doesn't affect survival after bone marrow transplant
Date:12/8/2008

SAN FRANCISCO ― Age alone should not determine whether an older patient with acute myeloid leukemia or myelodysplastic syndrome receives a blood stem cell transplant from a matched donor, researchers of the Center for International Blood and Marrow Transplant Research reported today at the 50th annual meeting of the American Society of Hematology.

Patients older than 65 do just as well as younger patients with transplants that are preceded by a milder chemotherapy regimen, according to an intensive analysis of every such transplant for AML or MDS conducted in North America between 1995-2005, said senior researcher Sergio Giralt, M.D., professor in The University of Texas M. D. Anderson Cancer Center Department of Stem Cell Transplantation and Cellular Therapy. The analysis also included international transplant data.

The retrospective study of 551 transplants for MDS and 565 for AML showed that age had no statistically significant impact on transplant-related mortality, relapse, leukemia-free survival or overall survival.

"These findings will be important in changing practice for the treatment of older patients," Giralt said. "We also hope the findings persuade the Centers for Medicaid and Medicare Services to recommend coverage of this therapy for MDS patients, as it does now for AML."

Findings will be presented at the meeting Monday morning by Dan McClune, D.O., of the University of Minnesota Masonic Cancer Center Department of Leukemia.

Matched donor, or allogenic, blood stem cell transplants originally were preceded with high-dose chemotherapy that destroyed the patient's blood supply before transplant. For patients over 65, this "myeloablative" chemotherapy was too toxic and therefore outcomes were poor.

Giralt and colleagues at M. D. Anderson pioneered the use of less-intensive chemotherapy that did not annihilate a patient's blood supply. This "non-myeloablative" preparation opened the do
'/>"/>

Contact: Scott Merville
smerville@mdanderson.org
713-516-4855
University of Texas M. D. Anderson Cancer Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Most Newer Antipsychotics No Better Than Older Ones, Just Different
2. Leading Government and Advocacy Stakeholders Engage in Public Health Dialogue on Improving Disposal of Unused Medications
3. Vitamin K Slows Insulin Resistance in Older Men
4. Varian Medical Systems Schedules Annual Stockholder Meeting in Palo Alto
5. 11.4% Shareholders & Former Executive Management of LCA-Vision Seek Board Representation and Executive Management Positions
6. MedQuist Announces Resolution of the DOJ Investigation and Dismissal of Shareholder Lawsuits
7. HLTH Corporation and WebMD to Webcast Annual Meetings of Stockholders
8. NUCRYST Receives Requisition to Call a Special Meeting of Shareholders From Majority Shareholder
9. The Westaim Corporation requisitions meeting of shareholders of NUCRYST Pharmaceuticals to return capital to NUCRYST shareholders
10. Older Adults Who Exercise Boost Blood Flow in Brain
11. Guideline Urges HIV Tests for All Patients 13 and Older
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... HealthDay Reporter , TUESDAY, Oct. 21, 2014 ... are only about half as likely as white women to ... indicates, and the racial disparity persists even when donor eggs ... white patients became pregnant after IVF, compared to about 17 ... cycles over two years to tease out the impact of ...
(Date:10/22/2014)... Salamon HealthDay Reporter TUESDAY, ... conventional in vitro fertilization (IVF) -- the incubation of embryos ... a device inside the vagina, new research suggests. Scientists ... called an INVOcell, might sharply cut costs for pricey IVF ... more accessible to those who don,t live near big-city assisted ...
(Date:10/22/2014)... HealthDay Reporter TUESDAY, Oct. 21, ... Ebola while working for NBC News in Liberia has ... isolation unit at Nebraska Medical Center in Omaha, where he had ... A blood test confirmed by the U.S. Centers for Disease ... to Providence, R.I., NBC News reported Tuesday night. ...
(Date:10/20/2014)... PA (PRWEB) October 20, 2014 Allegheny ... minimally-invasive procedure that enables physicians to repair a damaged ... The MitraClip system, developed by Abbott ... (MR), a progressive and life-threatening condition in which the ... blood to flow backward from the heart’s left ventricle ...
(Date:10/20/2014)... 20, 2014 Women’s health specialist, Dr. ... & Gynecology of Columbus, Inc., A Division of MaternOhio ... to more than 100,000 patients annually. Dr. Murphy will ... and stages of a women’s life. She is accepting ... in Westerville and Dublin. , Dr. Murphy offers a ...
Breaking Medicine News(10 mins):Health News:Black Women Fare Worse With Fertility Treatments, Study Says 2Health News:Black Women Fare Worse With Fertility Treatments, Study Says 3Health News:Experimental Infertility Treatment Seems Effective, Cheaper 2Health News:Experimental Infertility Treatment Seems Effective, Cheaper 3Health News:Experimental Infertility Treatment Seems Effective, Cheaper 4Health News:U.S. Cameraman Treated for Ebola 'Free' of the Virus 2Health News:U.S. Cameraman Treated for Ebola 'Free' of the Virus 3Health News:Allegheny General Hospital Introduces New, Beating-Heart Procedure for Mitral Valve Repair 2Health News:Allegheny General Hospital Introduces New, Beating-Heart Procedure for Mitral Valve Repair 3Health News:OhioHealth Welcomes New Women’s Health Specialist to MaternOhio Specialists in Obstetrics & Gynecology of Columbus, Inc. 2Health News:OhioHealth Welcomes New Women’s Health Specialist to MaternOhio Specialists in Obstetrics & Gynecology of Columbus, Inc. 3
... epic, a prince donates his youth to his father so that ... kind of help is at hand now. For scientists say they ... ageing process. And by manipulating that gene perhaps one could live ... in extending the lifespan of animals that are subjected to a ...
... According to the latest on breast-feeding, there is no hard and ... Most young mothers would be more than glad to ... feeding, can prove too painful for motherly feelings to override. ... a horrendous time trying to breastfeed when her daughter Deborah was ...
... nurse to avoid common errors which effect 1in 10 patients. ... workers help spread disease to unexpected quarters. ,The ... the world and lessen the number of health care related ... in both developed and developing countries. ,The nine ...
... higher levels of calcium and vitamin D are significantly more ... damage that can increase risk of cognitive impairment, dementia, ... co-investigators from Duke and the University of North Carolina examined ... (79 men, 153 women) between the ages of 60 and ...
... epidemic diseases has entered the phase of clinical experiments, claimed ... that rely on antigen or antibody test, the new technology ... or RNA, to confirm epidemic diseases such as hepatitis or ... of US National Institutes of Health (NIH). ,Xiang ...
... that can enable the blind to hear what they cannot see ... reads texts through an embedded system and converts them into voice ... it can only read text, but later it is likely to ... team that took six months to develop the device and the ...
Cached Medicine News:Health News:Gene Responsible for Ageing Process Discovered and Calorie Restriction Could Help 2Health News:New Research Promises To Take The Pain Off Breast Feeding 2Health News:New Research Promises To Take The Pain Off Breast Feeding 3Health News:UN Agencys Checklist on Health Care Error 2Health News:Higher Intake of Calcium and Vitamin D Linked With Brain Lesions in Older People 2
(Date:10/22/2014)... , Oct. 22, 2014   Reproductive Medicine ... leader in the field of infertility, presents new ... embryonic screening. The research abstract, released during the ... Medicine (ASRM) meeting in Honolulu, Hawaii ... single gene defect (SGD) pre-implantation genetic diagnosis (PGD). ...
(Date:10/22/2014)... A new report by Allied ... Form, End user, Application and Geography) - Size, Share, ... Opportunities, Segmentation and Forecast, 2013 - 2020", considers commercial ... key trends tracked, it is anticipated that the market ... 2020, registering a CAGR of 6.2% from 2014 to ...
(Date:10/22/2014)... 21, 2014   BioNano Genomics , the ... research centers to purchase an Irys™ System . ... Cancer Institute (NCI), NIH Intramural Sequencing Center (NISC) and ... obtaining a comprehensive view of a genome was ... does not deliver the scalability or reliability to ...
Breaking Medicine Technology:New IVF Research Highlights Improved Genetic Screening Approach To Help Parents Have Healthier Babies 2New IVF Research Highlights Improved Genetic Screening Approach To Help Parents Have Healthier Babies 3Global Disposable Gloves Market Expected to Grow to $7.9 Billion by 2020 - Allied Market Research 2Global Disposable Gloves Market Expected to Grow to $7.9 Billion by 2020 - Allied Market Research 3Global Disposable Gloves Market Expected to Grow to $7.9 Billion by 2020 - Allied Market Research 4BioNano's Irys System Adopted by Leading Genomics Centers for Comprehensive Detection of Human Genome Structural Variation 2BioNano's Irys System Adopted by Leading Genomics Centers for Comprehensive Detection of Human Genome Structural Variation 3
... KALAMAZOO, Mich., Jan. 3, 2011 Stryker Corporation (NYSE: ... its previously announced acquisition of the assets of the ... the approximately $900 million worldwide neurovascular market, which includes ... and ischemic stroke. "With the acquisition of ...
... MED Group, a Managed Health Care Associates, Inc. (MHA) ... website was created to help answer questions for Medicare ... competitive bidding and how patients can receive their medical ... for Medicare and Medicaid Services (CMS) will be implementing ...
Cached Medicine Technology:New Program for Medicare Beneficiaries Will Mean Major Changes Effective January 1, 2011 - The Carolinas 2New Program for Medicare Beneficiaries Will Mean Major Changes Effective January 1, 2011 - The Carolinas 3
... disposable pH catheter is used by ... for evaluating acid reflux events., ... pH monitoring. , ,Alpine's VersaFlex ... catheter on the market (4.7 French), ...
... pH catheters are efficient, economical, eliminate ... greater patient comfort during the test ... systems have been designed to use ... accurate room-temperature calibration. The temperature correction ...
FLEXILOG accessory....
FLEXILOG spare part....
Medicine Products: