Navigation Links
Older Diabetics Using Avandia Face Increased Death Risk
Date:12/11/2007

Canadian study also found those over 65 more likely to have heart trouble with drug

TUESDAY, Dec. 11 (HealthDay News) -- Older patients using the diabetes drug Avandia faced an increased risk of heart attack, heart failure and even death, new research shows.

According to the Canadian authors of the study, which is published in the Dec. 12 issue of the Journal of the American Medical Association, this is the first population-based look at the class of drugs to which Avandia belongs and the first report to find an increase in mortality rates.

"Our study looked at an older population in the real world who tend to be underrepresented in research trials and are at higher risk," said study author Dr. Lorraine L. Lipscombe, a researcher with the Institute for Clinical Evaluative Sciences in Toronto. "While the overall risk versus benefit is difficult to interpret in all people, in older people, the risks may outweigh the benefit."

"This is very striking data," added Dr. Steven Nissen, chairman of the department of cardiovascular medicine at the Cleveland Clinic Foundation. "This and other studies are going to put tremendous pressure on the FDA [U.S. Food and Drug Administration] to act more forcefully with regard to Avandia."

But the maker of Avandia (rosiglitazone), GlaxoSmithKline, took issue with the findings.

In a prepared statement, the company said the Canadian study "has significant limitations and generates misleading conclusions regarding acute myocardial infarction and death. These conclusions are inconsistent with a more robust body of evidence from large, long-term, prospective, well-designed clinical studies, including ADOPT and RECORD. These long-term trials in diabetic patients comparing rosiglitazone to other oral anti-diabetic medicines show no increased risk for cardiovascular events compared to other commonly used medications, other than the well-known risk of congestive hea
'/>"/>

Copyright©2007 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Ability to cope with stress can increase good cholesterol in older white men, study finds
2. Many Older Americans Have Active Sex Lives
3. Good Cholesterol Wont Help Heavy-Drinking Older Men
4. Manor Care, Inc. Announces Record Date for Special Stockholder Meeting
5. Arrow International Urges Shareholders To Vote for Approval of the $45.50 Teleflex Inc. Merger and for the Current Board of Directors
6. Manor Care, Inc. Announces Change of Location for Special Stockholder Meeting
7. Frequent alcohol consumption increases cancer risk in older women
8. Zimmer Holdings Offer and ORTHOsoft Directors Circular Mailed to Shareholders
9. ISS and Glass Lewis Recommend Cholestech Stockholders Vote FOR Merger
10. Glass Lewis Recommends Arrow Shareholders Vote on the White Proxy Card for Merger With Teleflex and for Current Board of Directors at Arrow Annual Meeting
11. Drug-free treatments offer hope for older people in pain
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Older Diabetics Using Avandia Face Increased Death Risk
(Date:12/19/2014)... LENEXA, Kan. (PRWEB) December 19, 2014 ... dedicated exclusively to healthcare providers, has been retained to ... for Johnson Memorial Hospital in Franklin, Ind. The top ... Smith has recently placed more than 900 healthcare executives ... 100-bed, county-owned, full service hospital providing care to the ...
(Date:12/19/2014)... (PRWEB) December 19, 2014 Pain Free ... is excited to announce a new Superior magnetic ... magnets. These are the strongest neodymium magnets for the ... Free Living developed the Superior Magnetics brand for the ... Free Living performs magnetic therapy using Superior Magnetic Jewelry ...
(Date:12/19/2014)... December 19, 2014 After a 13-year ... is again returning to the stage to entertain his ... for concert performances, and the successful tour has been ... announced. , Visit Ticketability.com for a ... Detroit shows at fair prices. , Music fans have ...
(Date:12/19/2014)... Dec. 18, 2014 (HealthDay News) -- Being in good shape ... report. They looked at data from more than 57,000 ... underwent treadmill tests between 1991 and 2009. Those in ... of having high blood pressure at the start of the ... high levels of fitness. Of the more than 8,000 ...
(Date:12/19/2014)... HealthDay Reporter THURSDAY, ... ibuprofen, might slightly reduce your risk of developing a ... ibuprofen (Advil, Motrin) and naproxen (Aleve) appear to reduce ... percent, the researchers concluded after reviewing nine prior studies. ... exposure. These painkillers "have potential as ...
Breaking Medicine News(10 mins):Health News:Johnson Memorial Hospital Retains B. E. Smith to Recruit New Chief Financial Officer 2Health News:Johnson Memorial Hospital Retains B. E. Smith to Recruit New Chief Financial Officer 3Health News:New Superior Magnetic Necklace Relieves Migraine Headache 2Health News:Garth Brooks Tickets for Joe Louis Arena: Ticketability.com Becomes a Popular Destination for Discount Tickets for Garth Brooks’ Detroit Concerts Set for February 27-28 2Health News:Being Fit Keeps Blood Pressure in Check 2Health News:Common Painkillers May Help Prevent Certain Skin Cancers, Study Finds 2Health News:Common Painkillers May Help Prevent Certain Skin Cancers, Study Finds 3
... LEXINGTON, Ky. (August 20, 2008) People at high risk ... or prevent the disease by taking certain food supplements and ... James W. Anderson, an internationally recognized authority on metabolic diseases ... nutrition at the University of Kentucky College of Medicine., ...
... says patients can still take the cholesterol-lowering drug ... drug regulators said Thursday that they were investigating ... to cancer. , The U.S. Food and Drug ... the agency was investigating a report from the ...
... BridgePoint Medical, LLC,s,partner, Charlotte Orthotic and Prosthetic Center ... COPC,s practitioner care team as Staff,Prosthetist and will ... facility., Amy is an ABC certified Prosthetist ... recently as a Staff Prosthetist / Orthotist with ...
... Aug. 22 AMN Healthcare Services,Inc. (NYSE: AHS ... make a presentation on Thursday, September 18, 2008 at ... Best Ideas Conference taking,place at the Omni Berkshire Place ... President and Chief Executive Officer of AMN,Healthcare, will present ...
... trends section contains insight on how the physician shortage is being ... ... (PRWEB) August 22, 2008 --- www.TDCpeople.com [The Delta Companies] ... Physician Recruiting Standard]], a free resource that provides a summary of ...
... understanding in the field of bioabsorbable polymers, Zeus presents free webinar ... ... August 22, 2008 -- Zeus, Inc., a leader in polymer science, ... cutting-edge bioabsorbables webinar entitled, "Bioabsorbable Polymers as Biomaterials." , , ,Presented ...
Cached Medicine News:Health News:'Nutraceuticals' could prevent diabetes 2Health News:FDA Investigates Possible Vytorin-Cancer Link 2Health News:FDA Investigates Possible Vytorin-Cancer Link 3Health News:Amy Street, Certified Prosthetist and Orthotist, Joins BridgePoint Medical Partner, Charlotte Orthotic and Prosthetic Center (COPC) 2Health News:AMN Healthcare Services to Present at the CL King 6th Annual Best Ideas Conference 2Health News:Physician Recruiting Standard Reveals Larger Populations Experiencing Increased Doctor Shortage 2Health News:Zeus Webinar: Bioabsorbable Polymers as Biomaterials 2
(Date:12/17/2014)... Tenn. , Dec. 17, 2014  Strategic Health ... management software solutions, today announced a strategic agreement with ... New Jersey regional marketplace.  This ... enhance the health and wellness solutions QualCare brings to ... and the surrounding region. QualCare plans ...
(Date:12/17/2014)... , December 17, 2014 ... less than a hub of information concerning the biopharmaceutical Group,s ... A further addition to the recently launched institutional website ... has now been enriched by a new chapter in the ... A richly detailed and panoramic hub on the world ...
(Date:12/17/2014)... Ga. and RALEIGH, N.C. ... Trial Marketing Communications, LLC (CTMC), and Integrated Clinical ... patient recruitment and retention for clinical trials announce ... Integrated Clinical Trial Marketing Services (i-CTMS). i-CTMS will ... retention services to pharmaceutical, biotechnology and medical device ...
Breaking Medicine Technology:Strategic Health Services to collaborate with QualCare on Population Health and Wellness Technology for QualCare Members 2Strategic Health Services to collaborate with QualCare on Population Health and Wellness Technology for QualCare Members 3Dompé Offers a New "Window" on the World of Scientific Research, with the http://www.dompetrials.com Website, Dedicated to Clinical Trials 2Dompé Offers a New "Window" on the World of Scientific Research, with the http://www.dompetrials.com Website, Dedicated to Clinical Trials 3Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 2Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 3
... 2, 2011 Sigma-Aldrich Corporation (NASDAQ: SIAL ... in September: KeyBanc Capital Markets 2011 ... at the InterContinental, Boston, MA, presenting at 9:00 AM ... September 14, at the Grand Hyatt, New York, NY, ...
... Sept. 2, 2011 On September 2, 2011, Vycor Medical, ... Quarterly Reports with the Securities and Exchange Commission for the ... fiscal year ended December 31, 2009 Form 10-Q (2nd Amendment) ... (2nd Amendment) for the fiscal quarter ended June 30, 2010 ...
Cached Medicine Technology:Sigma-Aldrich Corporation to Present at Upcoming Investor Conferences 2Vycor Medical, Inc. Files Restated Financial Statements 2Vycor Medical, Inc. Files Restated Financial Statements 3
Lacrimal Cannula, Curved - Open End, 21gSize: 21g x 1-1/2"....
Interchangeable design allows you to select a single handpiece and change tips during the procedure. Universal connector. Disassembles for easy cleaning. Tips can rotate 360 degrees to re-orient port...
Interchangeable design allows you to select a single handpiece and change tips during the procedure. Universal connector. Disassembles for easy cleaning. Tips can rotate 360 degrees to re-orient port...
Interchangeable design allows you to select a single handpiece and change tips during the procedure. Universal connector. Disassembles for easy cleaning. Tips can rotate 360 degrees to re-orient port...
Medicine Products: