Navigation Links
Older Dads May Raise Risk for Autism, Schizophrenia in Kids
Date:8/22/2012

By Carina Storrs
HealthDay Reporter

WEDNESDAY, Aug. 22 (HealthDay News) -- Men who have kids later in life may pass on more new genetic mutations to their offspring, possibly raising their child's risk of disorders such as autism and schizophrenia, new research suggests.

New mutations arise in the sperm cells of men near the time of conception instead of being passed down through generations. They have been associated with relatively rare cases of non-hereditary autism.

Researchers in Iceland searched the genomes of 78 families for new mutations as they first appeared and looked at how the number of these mutations in children was related to the age of their parents. In most of the families, the child had either non-hereditary autism or schizophrenia.

The study, which was published Aug. 22 in the journal Nature, found that every year a man ages, he is predicted to pass on more than two additional new (or "de novo") mutations. More than 97 percent of these new mutations in children were explained by having an older dad.

"The father is an incredibly important contributor to mutations, and even if de novo mutations happen randomly, the more mutations you have, the more likely you will have one in a gene that matters," said study author Dr. Kari Stefansson, CEO of deCODE Genetics, a genome analysis company based in Reykjavik, Iceland.

Previous research has linked higher rates of spontaneous mutations to older dads based on the sequence of select regions of the genome; this study is the first to make the connection based on data from the entire genome of parents and their children, Stefansson said.

"This study further establishes that paternal age is a risk factor for [non-hereditary] autism," said Daniel Smith, senior director of discovery neuroscience at Autism Speaks, an autism research and advocacy organization.

Although it is not known how many cases are autism are non-hereditary,
'/>"/>

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. RI Hospital researcher: Older women may not benefit from radiotherapy after breast surgery
2. Older Americans Living Longer, But Becoming More Obese
3. Older Antipsychotics May Work as Well as Newer Ones: Review
4. Not Enough Data to Advise Routine Hearing Screens for Older People: Experts
5. Study Questions Guidelines on Radiation for Older Breast Cancer Patients
6. Study: Majority of older, early-stage breast cancer patients benefit from radiation after lumpectomy
7. Weekend hospital stays prove more deadly than other times for older people with head trauma
8. Why do older adults display more positive emotion? It might have to do with what they’re looking at
9. Weekends More Fatal for Older Patients With Head Injury: Study
10. Low Vitamin D Levels May Raise Death Risk in Older Adults: Study
11. Mindfulness meditation reduces loneliness in older adults, Carnegie Mellon study shows
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Older Dads May Raise Risk for Autism, Schizophrenia in Kids
(Date:4/24/2014)... me out to the ballgame, doesn,t exactly conjure up ... likely culprits include French fries, soda and the occasional ... play youth baseball, eating unhealthy food during practices and ... researchers at Wake Forest Baptist Medical Center. The study, ... Obesity , found that high-calorie snacks and sugar-sweetened drinks ...
(Date:4/24/2014)... the new Institute for Biomedical Sciences at Georgia ... federal grant to develop novel therapeutics against Respiratory ... the Eunice Kennedy Shriver National Institute Of Child ... of Health will support Plemper,s drug development goals ... one distinct alternative compound. , Infections by RSV, ...
(Date:4/24/2014)... prescription opioid overdose deaths was outlined yesterday in the ... of agencies in the U.S. Department of Health and ... providers to expand their use of medications to treat ... number of misperceptions that have limited access to these ... can be used in combination with behavior therapies to ...
(Date:4/24/2014)... the first in the world to discover a gene ... jaw. , Ameloblastoma is an odontogenic tumour with a ... often found in the posterior of the lower jaw. ... deficiencies in the jaws as well as loss of ... need for surgery and the recurrence of ameloblastoma, but ...
(Date:4/24/2014)... The National Science Foundation has awarded LSU Health ... Undergraduates (REU) Site grant in the amount of ... undergraduates from diverse social and educational backgrounds, underrepresented ... area. The project will provide students with ... 2014-16. It will be led by Principal ...
Breaking Medicine News(10 mins):Health News:Take the bat, leave the candy 2Health News:HHS leaders call for expanded use of medications to combat opioid overdose epidemic 2Health News:HHS leaders call for expanded use of medications to combat opioid overdose epidemic 3Health News:HHS leaders call for expanded use of medications to combat opioid overdose epidemic 4
... a healthy diet appears to lower blood pressure in ... in women with high blood pressure, according to a ... ,The American Heart Association estimates that high ... 1 billion individuals worldwide. The most common-and deadly-result is ...
... here allegedly committed suicide Tuesday morning , with police attributing ... of the orthopaedics department, was found dead at around 7.00 ... south Delhi. ,Sharma, who is said to have ... around 6.00 a.m. to monitor his patients. After 20 minutes ...
... a super sleuth of potentially deadly prescription drug reactions. ... RADAR (Research on Adverse Drug Events and Reports) ... swoop in to investigate early signs of trouble years ... ,A new study by Bennett, the A.C. ...
... recently examined how researchers in Tanzania are training rats ... researchers' efforts "capitalize" on the rats' strong sense of ... ,Bart Weetjens, a former industrial designer, developed the idea ... land mines, after he visited minefields and saw German ...
... may be the disease generally identified with the third ... its tentacles everywhere. US authorities fear that an American ... flights this month to the potentially lethal disease. The ... authorities are looking for travelers who were aboard Air ...
... accumulating that depression is a risk factor for osteoporosis, ... Watch. A recent study found that people ages ... serotonin reuptake inhibitors (SSRIs) had double the rate of ... points to depression itself as a source of endocrine ...
Cached Medicine News:Health News:Soy Nuts may Improve Blood Pressure, Cholesterol Levels in Women 2Health News:Researchers Found Drug Effects of Deadly Prescription Well Before FDA 2Health News:Researchers Found Drug Effects of Deadly Prescription Well Before FDA 3Health News:Researchers Training Rats To Diagnose TB 2Health News:American Who Exposed Air Passengers to Drug Resistant TB Quarantined 2Health News:American Who Exposed Air Passengers to Drug Resistant TB Quarantined 3
(Date:1/15/2014)... , Jan. 15, 2014 Reportlinker.com announces ... available in its catalogue: ... Forecast and Market Analysis to 2022 ... Atopic Dermatitis - India Drug Forecast and ...
(Date:1/15/2014)... 2014 Reportlinker.com announces that a new ... catalogue: Global Markets ... -- Focus on End Users ... A drug delivery system is ...
(Date:1/15/2014)... CAMBRIDGE, Mass. , Jan. 15, 2014  Zafgen, ... the unmet needs of severely obese patients, today ... of beloranib, a selective inhibitor of methionine aminopeptidase ... a severe form of genetic obesity.  These results ...
Breaking Medicine Technology:PharmaPoint: Atopic Dermatitis - India Drug Forecast and Market Analysis to 2022 2PharmaPoint: Atopic Dermatitis - India Drug Forecast and Market Analysis to 2022 3PharmaPoint: Atopic Dermatitis - India Drug Forecast and Market Analysis to 2022 4PharmaPoint: Atopic Dermatitis - India Drug Forecast and Market Analysis to 2022 5Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 2Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 4Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 5Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 6Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 7Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 8Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 9Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 10Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 11Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 12Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 13Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 14Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 15Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 16Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 17Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 18Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 2Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 3Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 4
... 2009 Arena Pharmaceuticals, Inc. (Nasdaq: ARNA ) today reported ... Arena reported a lower net loss allocable to common stockholders in ... share, compared to a net loss allocable to common stockholders in ... share, and a net loss allocable to common stockholders in the ...
... TessArae® LLC, a global leader in resequencing microarray-based ... solutions for genetic testing of the mutations that ... TessArae,s expertise in microarray-based resequencing with novel nucleotide ... for all targeted mutations in multiple genes of ...
Cached Medicine Technology:Arena Pharmaceuticals Announces Third Quarter 2009 Financial Results and Recent Developments 2Arena Pharmaceuticals Announces Third Quarter 2009 Financial Results and Recent Developments 3Arena Pharmaceuticals Announces Third Quarter 2009 Financial Results and Recent Developments 4Arena Pharmaceuticals Announces Third Quarter 2009 Financial Results and Recent Developments 5Arena Pharmaceuticals Announces Third Quarter 2009 Financial Results and Recent Developments 6Arena Pharmaceuticals Announces Third Quarter 2009 Financial Results and Recent Developments 7Arena Pharmaceuticals Announces Third Quarter 2009 Financial Results and Recent Developments 8Arena Pharmaceuticals Announces Third Quarter 2009 Financial Results and Recent Developments 9TessArae Delivers Lower Cost Option to Genetic Testing Market 2
These simple but effective single-dose, hands-off, ampulized applicators have revolutionized skin preparation in hospitals....
... Anti-HTLV Mixed Titer Performance Panel consists of ... to strong positive for antibodies to HTLV ... for use by manufacturers and diagnostic laboratories ... data from all major test systems are ...
Comprised of a monofilament polypropylene mesh coated with hydrophilic porcine collagen, Pelvitex™ mesh is clinically proven coating to enhance the healing process, along with the strength and d...
The Repliform Tissue Regeneration Matrix is an acellular human dermal allograft that when surgically implanted is intended to function as a template, facilitating the body's fibroblasts to regenerate...
Medicine Products: