Navigation Links
Ohio State study: Targeted ovarian cancer therapy not cost-effective
Date:3/7/2011

eatment with standard chemotherapy drugs carboplatin and paclitaxel along with bevacizumab.

"We put together a model looking at the variety of treatment arms on this clinical trial, each of which included 600 patients," said Cohn. "Given the fact that the addition of the drug was associated with 3.8 months of additional survival without cancer, we set out to determine whether or not that benefit of survival was justified by the expense of the drug."

The model showed that standard chemotherapy for patients in the clinical trial would cost $2.5 million, compared to $78.3 million for patients who were treated with standard chemotherapy and bevacizumab, plus additional maintenance treatments of bevacizumab for almost one year.

Bevacizumab has been used in the treatment of recurrent ovarian cancer, and the U.S. Food and Drug Administration has approved it for the treatment of colorectal, lung, breast, brain (glioblastoma) and renal cell cancers.

Typically each treatment with bevacizumab costs $5,000, with most of those costs directly attributable to the cost of the drug, Cohn said.

Effectiveness was defined as months of progression-free survival, and costs were calculated as total costs per strategy. Cost-effectiveness strategies were defined as the cost per year of progression-free survival. Incremental cost-effectiveness ratio was defined as the costs per progression-free life-year saved.

"Ultimately, we found that if you reduced the drug cost to 25 percent of the baseline, it does become cost effective to treat patients with bevacizumab," said Cohn. "Or, if the survival could be substantially increased above the 3.8 months of progression-free survival, that could lead to cost-effective treatment for patients with advanced ovarian cancer."

Ovarian cancer is the most lethal gynecologic cancer, with almost 14,000 women expected to die from the disease this year, according to the American Cancer Society.

"It is anticipated that in the
'/>"/>

Contact: Eileen Scahill
Eileen.Scahill@osumc.edu
614-293-3737
Ohio State University Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. ACP applauds President Obamas call for state innovation on health insurance coverage
2. K-State chemists work brings more national recognition as promising early-career scientist
3. Rapid Rise in PSA Levels a Poor Predictor of Prostate Cancer: Study
4. Newer Drug May Help Prevent Fracture in Men With Prostate Cancer
5. PSA velocity screening for prostate cancer may lead to unnecessary biopsies
6. Change in PSA level does not predict prostate cancer
7. PSA Screening for Prostate Cancer Dips in Large U.S. Health Network
8. Wayne State University researchers publish results settling multiple sclerosis debate
9. Innovative International Healthcare Partnership established at Arizona State University
10. HJF signs distribution agreement for antibody to evaluate prostate cancer
11. 2010 AAAS Mentor Award goes to Dr. Joseph M. DeSimone of the University of North Carolina at Chapel Hill, and North Carolina State University
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... If you have asthma, you may have an asthma action ... and respond to changes and understand when symptoms are getting ... zone, you,re doing well, yellow means your asthma has worsened ... care. New guidelines are now available to help your allergist ... and away from the red zone. , "Management of acute ...
(Date:7/31/2014)... 31, 2014 Leelanau Peninsula’s newest winery, ... 2014 at 7788 East Horn Road in Lake Leelanau. Joining ... , Aurora Cellars is the 25th winery along the trail. ... popular wine tour events, making its trail event debut during ... , Owners David and Faye Mathia opened the boutique ...
(Date:7/31/2014)... 0-6 Pack Abs has finally been released by well ... James Vegher. Together they have launched a training program ... tone core muscles, improve posture, eliminate achy hips, and build ... to re-train the body in order to properly activate core ... Abs review, Shane Michaels, a fitness enthusiast, agrees that ...
(Date:7/31/2014)... Adventist Health System, which is ... Florida Hospital Tampa, Florida Hospital Carrollwood, Florida Hospital ... Pinellas, Florida Hospital Wesley Chapel, Florida Hospital Zephyrhills, ... Heartland Medical Center Lake Placid and Florida Hospital ... Most Wired Hospitals and Health Systems, which is ...
(Date:7/31/2014)... Los Angeles, CA (PRWEB) July 31, 2014 ... that will benefit both patients and doctors. Doctors will ... are allowed to leave reviews , which guarantees ... different treatment options on the site to receive information ... source. This unprecedented validation system allows Cosmetic Town ...
Breaking Medicine News(10 mins):Health News:Aurora Cellars Joins the Leelanau Peninsula Wine Trail 2Health News:Zero To Six Pack Abs System Review Exposes Tyler Bramlett And Dr. James Veghers’ New Ab Training Program 2Health News:Zero To Six Pack Abs System Review Exposes Tyler Bramlett And Dr. James Veghers’ New Ab Training Program 3Health News:Florida Hospital West Florida Region is Among the Most Wired Hospitals and Health Systems in the United States 2Health News:Cosmetic Town Improves Patient Experience Through Secure Verification of Patients and Doctors 2
... In a unique research effort, kin cancer researchers from all ... umbrella to help the world understand what exactly their risk ... the international Genomel consortium based in Leeds, England has been ... will lead the teams from around the world. All these ...
... Institute of Neurological Disease have found that the protein ... //that acts by inactivating the conversion of glucose into ... released from apoE. ,The apoE protein is ... not providing the glucose present in the brain to ...
... population runs a risk that is four times higher ... to the Australian Institute of Health and Welfare (AIHW).// ... attack. Between 2001 and 2003, almost 21,000 people aged ... diabetes. ,During the period under review ...
... religion plays in a patient's life positively affect physician bedside ... and no, for male medicos.// ,According to a ... Medical Journal, patients want their physicians to be aware of ... issues with them, especially if they are preparing for death. ...
... from an acute shortage of nurses, with some schools having ... across the country in schools on a fulltime basis.// This ... federal guidelines call for a nurse for every 750 students. ... when compared to other parts of the country. Because of ...
... his new book 'The Failure of Democratic Nation Building: Ideology ... that Democracy should not or cannot be forcibly thrusted on ... an intrinsic need for hierarchical and authoritarian social and political ... hand requires unique conditions before it is accepted by the ...
Cached Medicine News:Health News:Religious sensitivity of medicos gender-dependent 2Health News:School Children Put To Risk Due To Shortage Of Nurses 2
(Date:7/31/2014)... MONROVIA, Calif., July 31, 2014 Xencor ... biopharmaceutical company developing engineered monoclonal antibodies for the ... and cancer, today reported financial results for the ... review of recent business highlights. "In ... the American Thoracic Society 2014 International Conference (ATS) ...
(Date:7/31/2014)... Calif. , July 31, 2014  Cepheid (NASDAQ: ... speaking at the following conferences, and invited investors to participate ... Access Conference, New York, NY Wednesday, ... Baird Health Care Conference, New York, NY ... Time , Accessing Live Webcasts To access the ...
(Date:7/31/2014)... MOUNTAIN VIEW, Calif. , July 31, 2014 ... ) today provided an update on its pipeline ... of 2014, Alexza expects to initiate a Phase ... which is being developed for the management of ... identified two new Staccato -based product candidates ...
Breaking Medicine Technology:Xencor Reports Second Quarter 2014 Financial Results 2Xencor Reports Second Quarter 2014 Financial Results 3Xencor Reports Second Quarter 2014 Financial Results 4Xencor Reports Second Quarter 2014 Financial Results 5Xencor Reports Second Quarter 2014 Financial Results 6Xencor Reports Second Quarter 2014 Financial Results 7Xencor Reports Second Quarter 2014 Financial Results 8Cepheid to Webcast Upcoming Financial Presentations 2Alexza Provides Pipeline Update 2Alexza Provides Pipeline Update 3Alexza Provides Pipeline Update 4Alexza Provides Pipeline Update 5Alexza Provides Pipeline Update 6
Used for dilation of a tract to the kidney for removal of stones. Supplied sterile in peel-open packages. Intended for one-time use....
... musculofascial tract, renal capsule, and parenchyma during ... the catheter shaft. Radiopaque markers are placed ... the balloon. The radiopaque dilator/sheath assembly is ... coaxial placement of the sheath. Supplied sterile ...
... Therapy for Urinary Control offers a ... and the symptoms of overactive bladder, ... symptoms of urgency-frequency alone or in ... or could not tolerate more conservative ...
... Receiving timely, high-quality and accurate,ECG ... care. The,Quinton Eclipse Premier allows ... test results,and make a diagnosis ... sharing capabilities.,Workload is further streamlined ...
Medicine Products: