COLUMBUS, Ohio, and NEW YORKThe Ohio State University today announced the signing of an exclusive world-wide agreement with Microlin Bio Inc., licensing a large portfolio of Ohio State's groundbreaking cancer discoveries. The portfolio includes nearly 100 issued and pending microRNA patents that could lead to entirely new, more effective and more targeted ways to diagnose and treat prostate, ovarian, colon and lung cancers. Additionally, Microlin Bio Inc. has licensed a novel nucleic acid delivery technology to deliver these transformational therapies to cancer cells.
These technologies, years in the making, were developed by The Ohio State University Comprehensive Cancer Center Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC James) researcher Carlo Croce, M.D., The Ohio State University College of Pharmacy researcher Robert Lee, Ph.D., and collaborators from the National Cancer Institute with the National Institutes of Health.
Just over 10 years ago, Croce was the first in the world to link small cellular molecules called microRNA to cancer. MicroRNAs are now known to play a pivotal role in the growth and spread of many kinds of cancer, and they have shown great potential for transforming the diagnosis and treatment of cancer and other diseases.
Croce is a recognized world leader in cancer microRNA research. Ohio State has amassed one of the largest portfolios of microRNA technologies in the world.
"MicroRNAs have been the subject of study by my laboratory for more than a decade, and our work and the work of others has shown that the dysregulation of these molecules plays a critical role in the development of cancer and other diseases," says Croce, who is professor and chair of molecular virology, immunology and medical genetics, the John W. Wolfe Chair in Human Cancer Genetics and a member of the OSUCCC James Molecular Biology and Cancer Genetics Program.
"This licensing agreement w
|Contact: Darrell E. Ward|
Ohio State University Wexner Medical Center