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Office workers carry biomarker of potentially harmful flame retardant, study finds
Date:3/25/2013

n. In 2011, TDCPP was added to the Proposition 65 list of chemicals known by the State of California to cause cancer.

In vitro studies suggest TDCPP may be neurotoxic, and one study found that increased concentrations in dust were associated with decreased semen quality and reduced free thyroxine in men, suggesting possible effects on fertility and thyroid function. Animal studies show TDCPP is readily absorbed through both the skin and gastrointestinal tract.

The researchers said the high concentrations observed in dust from offices could reflect requirements by the City of Boston that office furniture meet California fire retardant standards, a rule that is not required of residential furniture in Boston. The state of California has proposed a draft furniture flammability standard that could reduce the need for flame retardant chemicals in polyurethane foam. However, the standard used for office furniture has yet to be revised.

"It is currently very difficult to avoid flame retardants. Hopefully, better options will become available in the near future," said Courtney Carignan, a doctoral candidate in environmental health who co-authored the study. "Currently, the best advice we have for people is to wash your hands, especially before eating. Dust control, good ventilation and air purifiers may also be useful for reducing personal exposure."

The low concentrations of TDCPP in the newer office building suggest that its newer furniture did not contain TDCPP, or that it had not yet had sufficient time to migrate out of the products, the researchers said. If the new furniture did not contain TDCPP, it likely contained a different flame retardant such as the controversial FireMaster 550. Other differences between exposures include the possibility of more efficient ventilation or HVAC systems or cleaning methods in the newer building.

The authors urged that "more research is needed to determine factors that influence TDCPP concentrations in dust, in
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Contact: Lisa Chedekel
chedekel@bu.edu
617-638-7721
Boston University Medical Center
Source:Eurekalert

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