Navigation Links
'Off-the-Shelf' Artificial Blood Vessels Show Promise
Date:4/24/2013

WEDNESDAY, April 24 (HealthDay News) -- Artificial blood vessels may one day reduce some complications of dialysis treatment in people with kidney failure, according to the results of early research in animals.

These so-called "off-the-shelf" blood vessels were implanted in the primates for six months and withstood frequent needle punctures, were not rejected by the immune system, remained free of blood clots, and were safely stored in a refrigerator for up to one year, the researchers said.

The findings were presented online Wednesday as part of the American Heart Association's Emerging Science Series. Based on the results, the researchers have started a clinical trial in Europe and have received U.S. Food and Drug Administration authorization for a clinical trial in the United States.

The artificial blood vessels are created by placing human aorta cells into a biodegradable mesh tube. The aorta is the largest artery in the human body. Within two months, a new blood vessel has developed and the mesh structure dissolves.

"Eventually, off-the-shelf blood vessel grafts might be used in kidney dialysis patients and potentially in many vascular procedures, such as bypassing blocked arteries in the legs, repairing vessel damage after trauma, or in coronary bypass operations," study lead author Shannon Dahl, co-founder and vice president of scientific operations at Humacyte, Inc., in Research Triangle Park, N.C., said in an American Heart Association news release.

Humacyte funded the study.

Before kidney failure patients begin dialysis, doctors surgically create a connection between an artery and a vein in the arm. But about half of kidney patients don't have healthy veins, so a synthetic blood vessel has to be used, Dahl explained.

These synthetic blood vessels have many complications and about half fail within a year, and the patients have to undergo surgery to replace them.

"The [new] artificial vessels had excellent resistance to obstruction and clotting and tolerated the repeated needle punctures required for dialysis," Dahl concluded in the news release.

Experts note that success in animal research often does not translate into success in human research. And the data and conclusions of unpublished research should be considered preliminary until published in a peer-reviewed journal.

More information

The National Kidney Foundation has more about dialysis.

-- Robert Preidt

SOURCE: American Heart Association, news release, April 24, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Artificial Ovaries Could Potentially Deliver Hormone Therapy
2. Wearable artificial lung to be developed at Pitt through $3.4 million grant
3. Artificial Pancreas Worked Overnight on Kids With Type 1 Diabetes
4. Swine cells could power artificial liver
5. Hear This: 3-D Printing Creates Lifelike Artificial Ears
6. Artificial Organs (Medical Bionic Implants) Market is expected to grow at a CAGR of 7.1% & to reach $17.82 billion by 2017 - New Report by MarketsandMarkets
7. Artificial pancreas: The way of the future for treating type 1 diabetes
8. FDA: Dont Use Pradaxa Blood Thinner in Patients With Artificial Heart Valves
9. A leap forward in the quest to develop an artificial pancreas
10. Artificial butter flavoring ingredient linked to key Alzheimers disease process
11. Farmers tough on artificial limbs
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
'Off-the-Shelf' Artificial Blood Vessels Show Promise
(Date:6/26/2016)... , ... June 26, 2016 , ... Brent Kasmer, a legally blind and certified personal ... personalized through a fitness app. The fitness app plans to fix the two major problems ... offer a one size fits all type program , They don’t eliminate all ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand ... project," said Christina Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s ... within Final Cut Pro X . Simply select a ProHand generator and drag ...
(Date:6/25/2016)... ... 25, 2016 , ... Conventional wisdom preaches the benefits of moderation, whether it’s ... setting the bar too high can result in disappointment, perhaps even self-loathing. However, those ... goal. , Research from PsychTests.com reveals that behind the tendency to ...
(Date:6/24/2016)... ... 24, 2016 , ... The Pulmonary Hypertension Association (PHA) learned ... receive two significant new grants to support its work to advance research and ... by recognizing patients, medical professionals and scientists for their work in fighting pulmonary ...
(Date:6/24/2016)... TX (PRWEB) , ... June 24, 2016 , ... People ... part in Genome magazine’s Code Talker Award, an essay contest in which patients and ... an award to be presented at the 2016 National Society of Genetic Counselors (NSGC) ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... ANDOVER, Mass. and SAN CLEMENTE, Calif. ... California -based mobile pulmonary function testing company, is now ... portable PFT devices developed by ndd Medical Technologies , Inc. ... PFT testing done in hospital-based labs.  Thanks to ndd,s EasyOne PRO ... CA , can get any needed testing done in the ...
(Date:6/24/2016)... India , June 24, 2016 ... Needles Market by Type (Standard Pen Needles, Safety Pen ... Therapy (Insulin, GLP-1, Growth Hormone), Mode of Purchase (Retail, ... by MarketsandMarkets, This report studies the market for the ... expected to reach USD 2.81 Billion by 2021 from ...
(Date:6/24/2016)... Belgium , June 24, 2016 ... the appointment of Dr. Edward Futcher ... Non-Executive Director, effective June 23, 2016.Dr. Futcher was ... Nominations and Governance Committees.  As a non-executive member ... independent expertise and strategic counsel to VolitionRx in ...
Breaking Medicine Technology: