Navigation Links
'Off-the-Shelf' Artificial Blood Vessels Show Promise
Date:4/24/2013

WEDNESDAY, April 24 (HealthDay News) -- Artificial blood vessels may one day reduce some complications of dialysis treatment in people with kidney failure, according to the results of early research in animals.

These so-called "off-the-shelf" blood vessels were implanted in the primates for six months and withstood frequent needle punctures, were not rejected by the immune system, remained free of blood clots, and were safely stored in a refrigerator for up to one year, the researchers said.

The findings were presented online Wednesday as part of the American Heart Association's Emerging Science Series. Based on the results, the researchers have started a clinical trial in Europe and have received U.S. Food and Drug Administration authorization for a clinical trial in the United States.

The artificial blood vessels are created by placing human aorta cells into a biodegradable mesh tube. The aorta is the largest artery in the human body. Within two months, a new blood vessel has developed and the mesh structure dissolves.

"Eventually, off-the-shelf blood vessel grafts might be used in kidney dialysis patients and potentially in many vascular procedures, such as bypassing blocked arteries in the legs, repairing vessel damage after trauma, or in coronary bypass operations," study lead author Shannon Dahl, co-founder and vice president of scientific operations at Humacyte, Inc., in Research Triangle Park, N.C., said in an American Heart Association news release.

Humacyte funded the study.

Before kidney failure patients begin dialysis, doctors surgically create a connection between an artery and a vein in the arm. But about half of kidney patients don't have healthy veins, so a synthetic blood vessel has to be used, Dahl explained.

These synthetic blood vessels have many complications and about half fail within a year, and the patients have to undergo surgery to replace them.

"The [new] artificial vessels had excellent resistance to obstruction and clotting and tolerated the repeated needle punctures required for dialysis," Dahl concluded in the news release.

Experts note that success in animal research often does not translate into success in human research. And the data and conclusions of unpublished research should be considered preliminary until published in a peer-reviewed journal.

More information

The National Kidney Foundation has more about dialysis.

-- Robert Preidt

SOURCE: American Heart Association, news release, April 24, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Artificial Ovaries Could Potentially Deliver Hormone Therapy
2. Wearable artificial lung to be developed at Pitt through $3.4 million grant
3. Artificial Pancreas Worked Overnight on Kids With Type 1 Diabetes
4. Swine cells could power artificial liver
5. Hear This: 3-D Printing Creates Lifelike Artificial Ears
6. Artificial Organs (Medical Bionic Implants) Market is expected to grow at a CAGR of 7.1% & to reach $17.82 billion by 2017 - New Report by MarketsandMarkets
7. Artificial pancreas: The way of the future for treating type 1 diabetes
8. FDA: Dont Use Pradaxa Blood Thinner in Patients With Artificial Heart Valves
9. A leap forward in the quest to develop an artificial pancreas
10. Artificial butter flavoring ingredient linked to key Alzheimers disease process
11. Farmers tough on artificial limbs
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
'Off-the-Shelf' Artificial Blood Vessels Show Promise
(Date:2/5/2016)... San Rafael, CA (PRWEB) , ... February 05, 2016 , ... ... partnership with ChildLight Yoga Studio in Dover, NH to direct high-performance kids yoga training. ... on New Hampshire’s seacoast, just one hour from Boston. , ChildLight Yoga Studio founder ...
(Date:2/5/2016)... New York, New York (PRWEB) , ... February 05, 2016 , ... ... in gym use and find themselves having to wait longer to access the treadmills. ... on their New Year’s resolutions to lose weight and get in shape by joining ...
(Date:2/5/2016)... ... February 05, 2016 , ... Pivot Point Consulting, a leading ... Software & Services for HIT Implementation Support & Staffing report with an outstanding ... performance by healthcare executives, managers and clinicians representing over 4,500 hospitals and 2,500 ...
(Date:2/5/2016)... ... 2016 , ... Stuart Bentkover, MD, FACS is thrilled to announce ... most effective tattoo removal today, Dr. Bentkover is the only doctor in Central Massachusetts ... PicoSure has been approved by the Food and Drug Administration (FDA) as a safe ...
(Date:2/5/2016)... ... 05, 2016 , ... In sleep, when the defenses of the day are ... of patients with eating disorders is significant self-criticism, and consequently these patients experience this ... regarded as maladaptive means for coping with this unease, but also leads to a ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... Ala. , Feb. 5, 2016  Patients in ... high intensity focused ultrasound (HIFU) therapy no longer have to ... to announce its partnership with Urology Centers of Alabama ... the newly FDA-cleared procedure for qualifying patients. ... their expertise in the treatment of prostate cancer using many ...
(Date:2/5/2016)... --> --> ... the global active pharmaceuticals ingredients (APIs) market stood at ... US$185.9 bn by 2020. It is expected to expand ... The title of the report is "Active Pharmaceutical Ingredients ... by Therapeutic Area) - Global Industry Analysis, Size, Share, ...
(Date:2/5/2016)... HARROGATE, England , February 5, 2016 ... --> Today, VoicePower Ltd - The Speech Recognition People, ... has been deployed to improve patient care, reduce turnaround times and ... ,- Wirral CCG ,- VoicePower client since 2013 Challenge: ... Challenge: --> - Six doctors ,- Wirral ...
Breaking Medicine Technology: