Navigation Links
Off-label drug use common, but patients may not know they're taking them, Mayo finds
Date:8/6/2012

Aug. 6, 2012

ROCHESTER, Minn. -- Many people have probably heard of off-label drug use, but they may not know when that applies to prescriptions they are taking, a Mayo Clinic analysis found. Off-label drug use occurs when a physician prescribes medication to treat a condition before that use has been approved by the Food and Drug Administration. In a newly published article in Mayo Clinic Proceedings, researchers pose and answer 10 questions about off-label drug use.

"Since the Food and Drug Administration does not regulate the practice of medicine, off-label drug use has become very common," says lead author Christopher Wittich, M.D., internal medicine physician at Mayo Clinic. "Health care providers and patients should educate themselves about off-label drugs to weigh the risks and benefits before a physician prescribes one or a patient takes one."

Some highlights from the article:

  • Off-label drug use is common. Within a group of commonly used medications, roughly 1 in 5 prescriptions were for an off-label use, a 2006 report found. Another study found that about 79 percent of children discharged from pediatric hospitals were taking at least one off-label medication.
  • Patients may not know when drugs they have been prescribed are being used off-label. No court decision has required that physicians must disclose, through informed consent, the off-label use of a drug, the authors say. The FDA makes clear that it doesn't regulate the practice of medicine and that the federal Food, Drug, and Cosmetic Act of 1938 doesn't make physicians liable for off-label drug use, they note.
  • Off-label drug use can become the predominant treatment for a condition. For example, some antidepressants are not approved by the FDA as a treatment for neuropathic pain, yet some drugs in this class are considered a first-line treatment option.
  • Examples of widely practiced off-label drug use include
    '/>"/>

Contact: Nick Hanson
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

0

GOOD

Page: 1 2

Related medicine news :

1. Off-Label Drug Use Appears Common
2. Reducing off-label use of antipsychotic medications may save money
3. Texting in College Classrooms Common, Distracting
4. Higher-spending hospitals have fewer deaths for emergency patients
5. Researchers uncover a viable way for colorectal cancer patients to overcome drug resistance
6. Vaccine yielded encouraging long-term survival rates in certain patients with NSCLC
7. Study finds doctors have exaggerated fears when starting patients on insulin
8. Diagnostic Scans Tied to Radiation Risk for Gastro Patients
9. Predictors identified for rehospitalization among post-acute stroke patients
10. Pulse pressure elevation could presage cerebrovascular disease in Alzheimers patients
11. Breast cancer patients suffer treatment-related side effects long after completing care
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... PHILADELPHIA, May 24, 2013 -- High blood glucose is ... of intensive insulin therapy (IIT) to control hyperglycemia is ... does not show a consistent benefit and even shows ... the American College of Physicians, (ACP) Clinical Guidelines Committee ... the American Journal of Medical Quality . , ...
(Date:5/23/2013)... Whether working in an urban setting or ... need an added layer of protection at night. ... , is an effective portable, rugged, rapidly deployable wireless ... border and perimeter security. , Today, ARA announces that ... over the past three years, with most systems deployed ...
(Date:5/23/2013)... 2013 In his pulse-quickening novel, “The AIDS ... “Do you trust your government?” , In the “The AIDS ... route to London ’s Heathrow Airport. His American colleague, ... waiting for him to arrive at his Sierra Nevada ... Alan has doubts about the government’s report. When Alan learns ...
(Date:5/23/2013)... Orange County film studio and visual effects designers, ... leaks for Apple's Final Cut Pro X today. , ... longer have to worry about matching up the movement in ... Christina Austin, CEO of Pixel Film Studios, "You have total ... , ProLeak from Pixel Film Studios allows users to take ...
(Date:5/23/2013)... Voyance, the ASC industry’s leading ... and ASCA, the industry’s national membership association, are ... Program. Voyance will leverage their decade ... experience to support ASCA’s goal to provide the ... , “Voyance is both excited and proud to ...
Breaking Medicine News(10 mins):Health News:ACP issues recommendations for management of high blood glucose in hospitalized patients 2Health News:Lighting Up the Night: ARA Announces Record Sales of Its Night VISER System 2Health News:Lighting Up the Night: ARA Announces Record Sales of Its Night VISER System 3Health News:New Book “The AIDS Covenant” by Roy Harris Delivers Intriguing, Captivating Story 2Health News:Pixel Film Studios Releases ProLeak Light Leaks for Final Cut Pro X Today 2Health News:Voyance and ASCA Announce Strategic Partnership to Better the ASC Industry 2Health News:Voyance and ASCA Announce Strategic Partnership to Better the ASC Industry 3
... now choose a gender of their liking and some can ... procedure developed at the All India Institute of Medical Sciences ... already given proper gender identities as males or females and ... the premier research and referral institute said. ,"Treatment ...
... now looking at lactate with a much more positive ... brain in the immediate //hours after a traumatic brain ... are right, it could change how emergency room physicians ... in the first critical hours after injury. ...
... screen all 20,000-plus human genes for biological activity, scientists have ... cancer cells are to certain chemotherapy drugs.// ,In ... edition of the journal Nature, researchers at UT Southwestern Medical ... molecules – the first used by a university research center ...
... in full bloom, the American Academy of Otolaryngology – Head ... can do to cope with the pollen in the air, ... // ,This spring, pollen from blooming trees and plants ... causing itching eyes, sneezing, nasal stuffiness, nasal congestion and drainage, ...
... may result in erectile dysfunction, decreased libido, anemia, sarcopenia, ... ,While a low serum testosterone level is ... hypogonadism on overall physical functioning and fall risk has ... 23 issue of the Archives of Internal Medicine, Orwoll ...
... than one-third of Queensland men have never been screened for ... ,Screening for colorectal cancer currently has stronger scientific ... prostate or skin cancer, but a new study in the ... undergo the colorectal cancer test than the other two. ...
Cached Medicine News:Health News:New Procedure Paves Way for Eunuchs to Choose a Gender and Conceive 2Health News:Study Challenges Conventional Treatment of Traumatic Brain Injury 2Health News:Gene Screening Points Way to More Effective Chemotherapy 2Health News:April Showers Bring May Flowers – And Plenty of Pollen, To 2Health News:Low Serum Testosterone Levels Associated With Fall Risk in Elderly Men 2
(Date:5/23/2013)... KNOXVILLE, Tenn. , May 23, 2013 /PRNewswire/ ... of 24-hour nurse triage and nurse advice lines, ... 10-person committee, comprising physician, nursing and administrative leaders, ... providing safe, quality and cost-effective services for hospital ... "As our national healthcare system evolves, it,s imperative ...
(Date:5/23/2013)...  Every day, their baby stopped breathing, his collapsed bronchus ... April and Bryan Gionfriddo watched helplessly, just ... "Quite a few doctors said he had a good chance ... Gionfriddo , about her now 20-month-old son, Kaiba. "At ... would take it and run with it." They ...
(Date:5/23/2013)... , May 23, 2013  Ameritox, the nation,s ... by Progressive Medical, Inc. to become part of ... clients manage pharmacy costs and improve the clinical ... a leading pharmacy benefit manager in the workers, ... medication compliance and pain management strategy for several ...
Breaking Medicine Technology:TeamHealth Medical Call Center Forms Clinical Advisory Committee 2Baby's life saved with groundbreaking 3D printed device from U-M that restored his breathing 2Baby's life saved with groundbreaking 3D printed device from U-M that restored his breathing 3Baby's life saved with groundbreaking 3D printed device from U-M that restored his breathing 4Ameritox Joins with Progressive Medical in Urine Drug Monitoring Network to Help Improve Care of Injured Workers 2Ameritox Joins with Progressive Medical in Urine Drug Monitoring Network to Help Improve Care of Injured Workers 3
... The new Bicycle ... electromagnetic braking system ... of reliable service ... operation. The hyperbolic ...
... 2000 Treadmill is advanced in patient ... extra-long, 60-inch treadmill surface provides an ... The Series 2000 Treadmill accelerates ... severely debilitated patients. Its extremely smooth ...
... systems feature our internationally-acclaimed algorithm that ... algorithm has a proven record for ... situations; and it's just one of ... recognized market leader in the stress ...
... 8000 is one of the ... systems for the exercise environment. ... our premiere exercise ECG system ... network connectivity, the CASE 8000 ...
Medicine Products: