Navigation Links
Obstructive sleep apnea is associated with diabetic peripheral neuropathy
Date:6/14/2012

Obstructive sleep apnea (OSA) is independently associated with diabetic peripheral neuropathy (DPN) in patients with type 2 diabetes mellitus (T2DM), according to a new study from researchers in the UK. The severity of DPN is also correlated with the degree of OSA and the severity of nocturnal hypoxemia.

"OSA is known to be associated with inflammation and oxidative stress, so we hypothesized that it would be associated with peripheral neuropathy in patients with T2DM," said lead author Abd Tahrani, MD, clinical lecturer in endocrinology and diabetes at the University of Birmingham in the UK. "This is the first report to identify an independent association between OSA and DPN in these patients."

The findings were published online ahead of print publication in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

In the observational cross-sectional study, DPN was assessed with the Michigan Neuropathy Screening instrument in 234 adults with T2DM. OSA was assessed with a single overnight home-based cardio-respiratory sleep study using a portable multi-channel device.

OSA was independently associated with DPN even after adjustment for a number of possible confounders, including ethnicity, gender, age at diabetes diagnosis, and diabetes duration, and remained independently associated with DPN after further adjustment for obesity and other risk factors for DPN. In addition, DPN severity was significantly correlated with OSA severity and nocturnal hypoxemia severity. The relationship between OSA severity and DPN severity remained significant after adjustment for age, obesity, diabetes duration, gender and estimated glomerular filtration rate.

The researchers also found that OSA was associated with increased nitrosative/oxidative stress and impaired microvascular blood flow regulation, which could explain the relationship observed between OSA and DPN. "In patients with T2DM, O
'/>"/>

Contact: Nathaniel Dunford
ndunford@thoracic.org
212-315-8620
American Thoracic Society
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Coffee Drinking in Pregnancy Wont Lead to Sleepless Baby: Study
2. Disrupted Sleep May Raise Risk for Obesity, Diabetes: Study
3. Depressed moms behavior may play role in infants sleep problems
4. Depressed Moms May Hinder Babies Sleep
5. Poor Sleep Heightens Ringing Ear Disease Symptoms: Study
6. Adjusting Your Attitude About Chronic Pain May Help You Sleep
7. Excessive sleepiness may be cause of learning, attention and school problems
8. Study: Kids Who Sleep in Parents Bed Less Likely to Be Overweight
9. Sleepwalking in Adults More Common Than Thought
10. Pediatric epilepsy impacts sleep for the child and parents
11. Parents Often Lose Sleep Over Childs Epilepsy, Study Finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... October 20, 2014 Succeed is proud to ... companies who participated in the Every Body Walk! ... public awareness project that encourages workers to be more active ... 10,000 Program, which concluded at the end of September, was ... cities and metro areas. Participating companies gave their staff ...
(Date:10/20/2014)... (PRWEB) October 20, 2014 Unveiled at the ... Strategic Direction Scorecard conservatively estimates member hospital ROI on membership ... on dues, The Center provides $12.50 in value to member ... (Member Value – Member Dues)/Member Dues. , “This is ... this number and we think the methodology is really sound,” ...
(Date:10/20/2014)... Do you ever feel difficulty in ... wonderful app Metassessor for teachers, specialists and parents. SIMpalm, ... its client “Intervention Development LLC” to launch Metassessor App ... for iOS 4.3 or later and is Compatible with ... for iPhone 5. It is now available on Apple ...
(Date:10/19/2014)... (PRWEB) October 19, 2014 Dr. Babatunde ... Fund, welcomes news of a ceasefire agreement that is ... than 200 girls who were kidnapped from the north-eastern ... languished in captivity long enough, and it is high ... communities," stated Dr. Osotimehin. , "We owe it to ...
(Date:10/19/2014)... (PRWEB) October 20, 2014 Recently, Fancyflyingfox.com, ... special occasion clothes, has announced its latest designs of ... addition, all the new elegant outfits are offered with ... place an order before October 30 can enjoy this ... and great marketing strategies, it has become one of ...
Breaking Medicine News(10 mins):Health News:Succeed Management Solutions, LLC Competes in Walking Challenge and Achieves 12th Place in Portland 2Health News:Scorecard Estimates Hospital ROI at $12.50 for every $1 Spent on Dues 2Health News:Scorecard Estimates Hospital ROI at $12.50 for every $1 Spent on Dues 3Health News:Scorecard Estimates Hospital ROI at $12.50 for every $1 Spent on Dues 4Health News:Metassessor App Launched: an RTI tool for Teachers & Parents 2Health News:Metassessor App Launched: an RTI tool for Teachers & Parents 3Health News:Fancyflyingfox.com Updates Its Website With New Mother Of The Bride Dresses For 2014 2
... before it can expect developing nations such as China and India ... ,While a world framework on cutting emissions should involve ... in fighting climate change, Schwarzenegger said today in a press conference ... ,"We can't go to India and China and say, 'This is ...
... fertility of rats, believe many in Mizoram. Now nutrient-rich bamboo ... Mizo menu and even the bedroom! ,In Mizoram, ... tall grass every 50 years are considered a harbinger of ... trigger a phenomenal rodent population explosion as the rats eat ...
... only hit drier cities like the Indian capital but also ... a UN report released Wednesday. ,"Much of ... which they were first displaced," says the 'State of the ... (Unfpa). ,"Drought, flooding and the other consequences of ...
... of the fight against drug addiction and some soulful music ... the International Day Against Drug Abuse. ,'Celebrating ... recovering drug abusers from across the society to participate and ... the ministry of social justice and empowerment and the United ...
... The United Nations is pressing ahead with its campaign against ... skeptics might say. ,It has now come ... the "greatest environmental challenge of our times" and could set ... ,The report called on governments in arid regions to revise ...
... President, Dr Rosanna Capolingua, today welcomed Labors preventative health ... to addressing Australias future health needs. ,Dr ... and the increasing incidence of chronic disease in the ... on the health budget and the medical workforce in ...
Cached Medicine News:Health News:Bamboo Seed: Viagra and Food for Mizos 2Health News:Puppet Show, Music Gives Message - 'say No to Drugs' 2Health News:Desertification, a Major Threat, Says UN 2Health News:Labor's Preventive Health Care Policy Looks to Address Future Needs 2
(Date:10/20/2014)... octubre de 2014  PneumRx, Inc. ( www.pneumrx.com ... pulmonología intervencional, anunció hoy la conclusión de la ... antes de lo programado. El Estudio Clínico RENEW es ... investigación (IDE) aprobada por la FDA (Administración de ... de reducción de volumen pulmonar PneumRx RePneu, un ...
(Date:10/20/2014)... , Oct. 20, 2014 Valeritas, Inc., ... designed for patients with Type 2 diabetes, announced today ... Chain Excellence Award. The award was presented October 16 ... Columbus, Ohio . ... judged across a variety of metrics specifically targeted at ...
(Date:10/20/2014)... , Oct. 20, 2014 Lpath, ... leader in bioactive lipid-targeted therapeutics, received official notification from ... been granted another key patent supporting its iSONEP™ ... issued patent, European patent No. 2087002, claims compositions ... in Lpath,s two lead compounds, iSONEP and ASONEP. ...
Breaking Medicine Technology:PneumRx concluye inscripción en prueba fundamental RENEW 2PneumRx concluye inscripción en prueba fundamental RENEW 3Valeritas Receives 2014 Cardinal Health Supply Chain Excellence Award 2Valeritas Receives 2014 Cardinal Health Supply Chain Excellence Award 3Lpath Granted Key European Patent Related to iSONEP and ASONEP Programs 2Lpath Granted Key European Patent Related to iSONEP and ASONEP Programs 3Lpath Granted Key European Patent Related to iSONEP and ASONEP Programs 4
... , WILMINGTON, Del. ... System is taking a giant leap forward toward a ... Order Entry (CPOE), technology that makes it easier, more efficient ... (Logo: http://www.newscom.com/cgi-bin/prnh/20090407/DC95299LOGO ) , The system goes live on ...
... , HOFFMAN ESTATES, Ill. , Jan. 28 ... Drug Administration (FDA) has given 510(k) marketing clearance to both ... , The DYNA-LINK system features a next-generation stand-alone device that ... is a thoracolumbar plating system that features multiple types of ...
Cached Medicine Technology:Christiana Care Health System Rolls Out Electronic Computerized Provider Order Entry 2
... Utilizing the most complex grinding ... accurate trial lens, are specifically ... quality and precision as the ... marco RT-300 refractor. Marco custom ...
Non-Illuminated Trial Lens Set with lenses mounted in plastic frames....
Illuminated Trial Lens Set is an attractive set of trial lenses worked to a high standard of accuracy....
Minus cylinders only trial lens set....
Medicine Products: