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Obio Pharmaceutical Announced New Antiviral Drug Discovery to Combat Influenza Virus
Date:3/10/2009

HONG KONG, March 10 /PRNewswire-Asia/ -- Obio Pharmaceutical Holdings Ltd ("Obio"/ "the Company") announced the discovery of a new indication of a drug, TG21, against main strains of influenza virus (including avian and human influenza strains) such as H3N2 and H5N1. The process leading to clinical trials for TG21 has already commenced.

"Obio has and will continue to engage prestigious institutions in USA and China to conduct various researches, all of which have endorsed that TG21 has antiviral effect towards a wide spectrum of influenza virus. Testing on chick embryo, chick, and mice are conducted. The finding indicated TG21 can increase the survival rate and decrease the amount of virus of animals challenged by Avian Influenza virus H5N1. TG21 possesses a complete safety profile as the active ingredient of the compound is already a drug approved by the US Food and Drug Administration (FDA) and EU European Medicines Agency (EMA) for chronic use to treat a rare disease, and there are no serious side effects recorded." Dr. Bill Piu Chan said.

After years of study to prove the efficacy of TG21 in tackling influenza virus, scientists are still investigating the basic mechanism of TG21. However, it is certain that TG21 works on a different mechanism to that of both Tamiflu(TM) and Relenza(TM). The two readily available drugs are Neuraminidase Inhibitors that prevent the virus from spreading to other cells. Both of them have similar antiviral mechanisms towards influenza virus.

Delivered in pills, Tamiflu(TM) and the inhaler drug-Relenza(TM) are the only drugs suggested by US FDA and World Health Organization for treating and preventing avian flu infection at present. However, cases of resistance to the mainstream medical intervention-Tamiflu (TM) are on the rise as shown in reports by U.S. Center of Disease Control and Prevention and the EU-Supported Network for Vigilance against Viral Resistan
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SOURCE Obio Pharmaceutical Holdings Limited
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