Navigation Links
Obesity research boosted by watching hunger in the brain
Date:11/7/2007

Scientists can now measure how full or hungry a mouse feels, thanks to a new technique which uses imaging to reveal how neurons behave in the part of the brain which regulates appetite.

Researchers hope the technique, which uses magnetic resonance imaging, will enable a far greater understanding of why certain people become obese when others do not, and why different people have different appetites. The new study, led by researchers from Imperial College London, is described in a paper published today in the Journal of Neuroscience.

It had previously been very difficult to measure satiety, which is the psychological feeling of being full and satisfied rather than physical fullness. To judge satiety scientists have relied on asking volunteers in trials how full they feel, or watching how much food is eaten, rather than using more objective measures.

Scientists had already identified the part of the hypothalamus area of the brain which regulates appetite. In the new study, the researchers discovered that they could see the neurons there firing if they used a contrast agent of manganese ion to make the neurons visible on a magnetic resonance imaging scan.

When the mouse was hungry and hence the neurons showed increased activity, the contrast agent was taken up, making the neurons light up on the scan. The intensity of this signal decreased as the mouse became less hungry and the neurons became less active.

Scientists already use different contrast agents to look at the anatomy of different cells in the body. The new research is the first to identify which contrast agent is taken up by the hunger neurons and hence allow researchers to observe how they behave in response to different stimuli.

Professor Jimmy Bell, corresponding author of the study from the MRC Clinical Sciences Centre at Imperial College London, said: Appetite and appetite control are important components of why people put on weight. We know v
'/>"/>

Contact: Laura Gallagher
L.Gallagher@imperial.ac.uk
44-020-759-46702
Imperial College London
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Virus Could Help Drive Obesity
2. Surgery for severe obesity saves lives
3. Obesity Doesnt Always Equal Diabetes
4. Obesity Rate in U.S. Still Climbing
5. Treating diabetes during pregnancy can break link to childhood obesity
6. ZIP codes and property values predict obesity rates
7. High and mighty: first common height gene identified by researchers behind obesity gene finding
8. Research Links TV/Video Game Playing With Child Obesity; Health Experts Back a New Approach
9. UT Southwesterns obesity research receives $22 million NIH Roadmap grant
10. Genaera Announces Formation of Scientific Advisory Board for Obesity Drug Candidate Trodusquemine (MSI-1436)
11. Cities Say Restaurant Nutrition Information Crucial in Fighting Obesity
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... Deer Path of Huntley -- a BMA affordable ... from 3 p.m. to 4 p.m. on Feb. 13. , The ... serves adults with physical disabilities between the ages of 22 and ... games and sweetheart-themed karaoke. , For more information about the event ...
(Date:1/22/2015)... PA (PRWEB) January 22, 2015 Woodloch Pines, ... Mountains, has been selected by TripAdvisor as the number one ... the 6th best in the world for their annual Travelers’ ... online travel community . The website is home to millions ...
(Date:1/22/2015)... a famous wedding dress company offering many trendy designs. Today, ... Twitter, and Pinterest. The fans will have an opportunity to ... week. , Moreover, the company has extended its 2015 New ... for more information. , Angelweddingdress is a famous ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 A new ... of experience and person-centeredness in the long-term care environment ... action across the continuum. The paper, “The Power of ... engages perspectives and practices of the patient, resident and ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Joan Lunden, ... keynote speaker at the upcoming 32nd Annual Miami ... Physicians’ Education Resource®, LLC (PER®) , shares that ... have gone undetected if she had not followed up ...
Breaking Medicine News(10 mins):Health News:Deer Path of Huntley Affordable Assisted Living to Host Valentine's Day Happy Hour 2Health News:TripAdvisor Names Woodloch Pines Best Hotel for Families in America 2Health News:TripAdvisor Names Woodloch Pines Best Hotel for Families in America 3Health News:Angelweddingdress Invites Its Customers To Follow It On Facebook, Twitter, And Pinterest 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 2Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 4Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 5Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 6
... obesity: heart health. , ... Phoenix, AZ (Vocus) January ... February as "American Heart Month". Typically this is the month of ... most Americans are reminded about the causes of heart disease. A ...
... need to be cut out of system in coming ... health-care reform becomes a reality, most Americans can expect ... 2016, a new report claims. , Left unchecked, the ... to $24,291 in the next seven years, according to ...
... following a heart attack are at a significantly higher ... widely used acid-lowering medications called proton pump inhibitors, a ... found ( http://www.cmaj.ca/cgi/rapidpdf/cmaj.082001 ). , The study, conducted over ... 66 years and older, found a significantly increased risk ...
... Obama,s Call to Computerize All Health Records Within Five ... Systems Society (HIMSS), representing more than 20,000 individual members ... and 350 corporate members, today announced its support for ... Recovery and Reinvestment Plan of 2009 proposed by Congress. ...
... on Long-Term Investment in America,s FutureWASHINGTON, Jan. 28 ... time in the past quarter century amid the worst ... Future co-director Robert Borosage urged progressives who ... rally around an historic opportunity to rebuild America. Borosage ...
... (ILS), a,management services company focused on introducing managed care ... announced the appointment of,The Honorable Josefina G. Carbonell as ... will lead the strategic growth of the company,s,long-term care ... Florida aging community. , (Photo: ...
Cached Medicine News:Health News:Celebrate American Heart Month with a Treadmill Desk 2Health News:Celebrate American Heart Month with a Treadmill Desk 3Health News:Skyrocketing Health-Care Costs Could Double Premiums for Many Americans 2Health News:Skyrocketing Health-Care Costs Could Double Premiums for Many Americans 3Health News:Proton pump inhibitors increase risk of heart attacks for patients on common cardiac drug 2Health News:Electronic Health Records: The Time is Now 2Health News:Former Assistant Secretary for Aging, The Honorable Josefina G. Carbonell, Appointed Senior Vice President at Independent Living Systems 2
(Date:1/23/2015)... BOSTON , January 23, 2015 ... development company, is delighted to announce that the Malcolm ... Miles Congreve (Vice President of Chemistry), Fiona ... Weir (Chief Executive Officer and co-founder) for the seminal ...
(Date:1/22/2015)...  Uroplasty, Inc. (NASDAQ: UPI ), a medical device ... to treat voiding dysfunctions, today reported financial results for ... Global revenue for the Company,s Urgent ®  PC ... quarterly revenue record, as compared to $3.9 million in ...
(Date:1/22/2015)... , Jan. 22, 2015  Bio-Techne Corporation (NASDAQ: ... Ella, the first member of the new Simple Plex ... brand.  This launch represents the re-branding of the previously ... Simple Plex platform is a transformative immunoassay technology which ...
Breaking Medicine Technology:Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 2Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 3Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 4Uroplasty Reports Record Revenue in Fiscal Third Quarter 2Uroplasty Reports Record Revenue in Fiscal Third Quarter 3Uroplasty Reports Record Revenue in Fiscal Third Quarter 4Uroplasty Reports Record Revenue in Fiscal Third Quarter 5Uroplasty Reports Record Revenue in Fiscal Third Quarter 6Uroplasty Reports Record Revenue in Fiscal Third Quarter 7Uroplasty Reports Record Revenue in Fiscal Third Quarter 8Uroplasty Reports Record Revenue in Fiscal Third Quarter 9Uroplasty Reports Record Revenue in Fiscal Third Quarter 10Uroplasty Reports Record Revenue in Fiscal Third Quarter 11Uroplasty Reports Record Revenue in Fiscal Third Quarter 12Uroplasty Reports Record Revenue in Fiscal Third Quarter 13Uroplasty Reports Record Revenue in Fiscal Third Quarter 14Uroplasty Reports Record Revenue in Fiscal Third Quarter 15Uroplasty Reports Record Revenue in Fiscal Third Quarter 16Uroplasty Reports Record Revenue in Fiscal Third Quarter 17Uroplasty Reports Record Revenue in Fiscal Third Quarter 18Bio-Techne Launches Simple Plex Platform 2Bio-Techne Launches Simple Plex Platform 3
... 96-well microplate washer designed to ... air pressure, and aspiration and ... On-board software for user to ... vacuum pump required. Ideal for ...
Space-saving counter top model,User initiated manual defrost,Standard features (see above),Internal freezing compartment,Removable half-shelf in refrigerator,Two shelves in door,UL 471 Commercial Ref...
... 8000 L/day of Type III Laboratory-grade Water, ... produce up to 8000 L/day of Type ... One Complete Purification and Control Unit, RiOs ... system, providing total control of all parameters ...
... Up to 8000 L/day of Type III ... designed to produce up to 8000 L/day ... tap feedwater., One Complete Purification and Control ... a centralized system, providing total control of ...
Medicine Products: