Navigation Links
Obesity raises risks of serious digestive health concerns
Date:8/19/2008

Bethesda, MD, August 19, 2008 The prevalence of obesity and overweight in the United States coupled by the increased risk of gastrointestinal diseases related to obesity raises serious implications for the health of Americans. Several scientific studies in the August issue of The American Journal of Gastroenterology examine the association between obesity and the risk of colorectal cancer and gastroesophageal reflux disease, or GERD.

Dr. Frank K. Friedenberg and colleagues from Temple University School of Medicine in Philadelphia provide an extensive overview of scientific research on the epidemiologic and pathophysiologic associations between obesity and GERD.

Several studies featured in the article highlight the correlation between increasing body mass index (BMI) and the frequency and severity of acid reflux symptoms. One particular study found that accumulation of abdominal fat, as measured by the waist-to-hip ratio, may be the most important risk factor for the development of acid reflux and related complications such as Barrett's esophagus and esophageal adenocarcinoma.

The authors also examined data on the effects of weight loss through diet or surgical methods on acid reflux disease. Several studies suggest weight loss through caloric restriction was beneficial in reducing GERD symptoms. When the authors compared the different surgical approaches for weight loss, a surgical technique called "Roux-en-Y" gastric bypass appeared to be the best method, and was most consistently associated with improvement in the symptoms and findings of GERD. "The mechanism of action through which this surgery is successful at improving GERD may be independent of weight loss and needs further examination," said Dr. Friedenberg.

High Body Mass Index Increases Risk of Colorectal Adenomas

Researchers at the University of Tokyo and Kameda General Hospital in Japan examined the effect of body weight on the incidence of colorectal adenoma in 7,963 Japanese patients who underwent colonoscopy between 1991 and 2003. Patients who had a family history of colorectal cancer, colorectal polyps, inflammatory bowel disease, colorectal surgery or who took NSAIDS were excluded from the study.

In this cross-sectional study, patients were classified into four groups according to their body mass index (BMI). Researchers found 20.7 percent of patients had at least one colorectal adenoma. Importantly, as the BMI increased, so did the prevalence of colorectal adenomas.

In a separate cohort analysis, 2,568 patients from the initial study underwent a second colonoscopy after one year to compare the effect of body weight changes on the development of new colorectal adenomas. The incidence rates of colorectal adenoma were 9.3 percent in patients who lost 5 percent or more in body weight; 16.2 percent in patients who gained 5 percent or more in body weight; and 17.1 percent in patients who neither gained nor lost weight.

Weight loss was associated with lowered incidence of adenoma, independent of gender, age, initial colonoscopic findings, and initial BMI. Based on their findings, the authors suggest that controlling body weight may decrease the risk of developing colorectal adenomas.

According to ACG President Amy E. Foxx-Orenstein, D.O., FACG, "The magnitude of the obesity epidemic adds a staggering burden to our current health care system. These studies point to the serious potential risks of GI disease for individuals who are overweight or obese."


'/>"/>

Contact: Rosanne Riesenman
rriesenman@acg.gi.org
301-263-9000
American College of Gastroenterology
Source:Eurekalert

Related medicine news :

1. Poor Coordination in Childhood Tied to Adult Obesity
2. Video: Ochsner Medical Center Drives Mobile P.E. Class to New Orleans Schools in Fight Against Child Obesity
3. Scientists measure connection between the built environment and obesity in baby boomers
4. Scientists Create Mice Resistant to Obesity
5. YMCA Calls on Senate to Fund Community-Based Solutions to Address Childhood Obesity Crisis
6. Chicago-Based Speaker/Author Concurs with Research Finding of Using Journaling as a Tool to Combat Obesity and Other Health Problems
7. Responding to Increased Incidence of Obesity and Associated Health Issues, The HealthCentral Network Launches Site to Support those Struggling with Weight
8. Kids Obesity May Lead to Epidemic of Adult Diabetes
9. Herbal remedy reduces obesity and heart disease?
10. ADHD Might Raise Kids Obesity Risk
11. Population-Based Strategy Urged to Cut U.S. Obesity Rate
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2017)... ... August 22, 2017 , ... “Wilderness Voices”: a collection of ... “Wilderness Voices” is the creation of published author, Martha McKown, an ordained United ... inspired as a very young child when her older sisters studied High School literature. ...
(Date:8/22/2017)... ... August 22, 2017 , ... “Covert Awakening”: Walid’s ... of published author, Julianne Hale, a consultant for the Intelligence Community. For ... focusing on the Near East region. Julianne has written hundreds of reports ...
(Date:8/22/2017)... , ... August 22, 2017 , ... ... Stewart is the Founder and Managing Member for t4 Leadership Development & Consulting. ... critical to his definition of “success”: physician leadership development, servant leadership, data driven ...
(Date:8/22/2017)... ... ... “Call Of Spiritual Duty”: a revelation in an era defined by intentional ... Growing up on the streets of North Visalia, California, Carlos Lizarde quickly became familiar ... keys to his life, he noticed immediately that opportunities and blessings began to shift ...
(Date:8/21/2017)... ... August 22, 2017 , ... PracticeMatch, a company that ... healthcare employers connect with physicians and advanced practitioners like nurse practitioners and ... in August through November of this year. The online career fairs will allow ...
Breaking Medicine News(10 mins):
(Date:7/31/2017)... , July 31, 2017 Three Tru-D SmartUVC ... South Korea . Tru-D, short for "Total Room Ultraviolet ... operating rooms after an environmental services (ES) professional cleans the area with ... ... "Although the BAACH ...
(Date:7/27/2017)... 27, 2017  Zimmer Biomet Holdings, Inc. (NYSE and ... June 30, 2017.  The Company reported second quarter net ... the prior year period, and an increase of 2.1% ... points of contribution from the LDR Holding Corporation acquisition, ... quarter of 2016, or 0.3% on a constant currency ...
(Date:7/26/2017)... , July 26, 2017 Sancilio Pharmaceuticals Company, ... our clinical trial evaluating Altemia TM , an oral ... and Sickle Cell Disease (SCD). The SCOT Trial, is ... efficacy and safety of Altemia TM in pediatric ... under US IND 125274. ...
Breaking Medicine Technology: