Navigation Links
Obesity predicts inadequate bowel prep at colonoscopy
Date:5/31/2009

Bethesda, MD (June 1, 2009) Obesity is an independent predictor of inadequate bowel preparation at colonoscopy, and the presence of additional risk factors further increases the likelihood of a poorly cleansed colon, according to a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association (AGA) Institute.

Obesity has become an epidemic in the present era, both in the U.S. and in other developed nations. Abnormal elevation of body mass index (BMI) is associated with several gastrointestinal diagnoses, including diverticular disease, gastroesophageal reflux disease, colon polyps and colon cancer.

Since the majority of colon cancers arise from adenomatous (benign) colon polyps, proper screening becomes crucial while performing colonoscopy on obese patients. An inadequately cleansed colon can jeopardize the effectiveness of screening or surveillance colonoscopy, exposing these patients at higher risk for colorectal tumors to the dangers of missed lesions and higher cost of repeat colonoscopy.

"The implications of our findings are profound. Since over a quarter of all patients had an inadequate examination, identification of a patient profile with a high risk for poor colon preparation will be helpful in capturing those who would benefit from an initial individualized designer preparation regimen," said Brian Borg, MD, of Washington University in St. Louis, MO and lead author of the study. "Our results suggest that the obese patient should at least be subject to more precise instructions and possibly a more rigorous bowel preparation regimen. In addition, as the number of risk factors for an inadequate bowel preparation increase, the need for early repeat colonoscopy escalates."

In this study, believed to be the first of its kind, patients were designated overweight when BMI was ≥25 and obese when ≥30. All colonoscopy procedures performed at a tertiary referral center over a four-month period were evaluated. Bowel preparation was assigned a unique composite outcome score that took into account a subjective bowel preparation score, earlier recommendation for follow-up colonoscopy due to inadequate bowel preparation and the endoscopist's confidence in adequate evaluation of the colon. Univariate and multivariate logistic regression analyses were performed to identify the role of BMI in predicting an inadequate bowel preparation.

During the study period, 1,588 patients fulfilled inclusion criteria. An abnormal BMI (≥25) was associated with an inadequate composite outcome score. In multivariate logistic regression analyses, both BMI ≥25 and ≥30 were retained as independent predictors of inadequate bowel preparation. Each unit increase in BMI increased the likelihood of an inadequate composite outcome score by 2.1 percent. Additional independent predictors of inadequate preparation exponentially increased the likelihood of an inadequate composite outcome score; seven additional risk factors identified 97.5 percent of overweight patients with an inadequate composite outcome score.


'/>"/>

Contact: Alissa J. Cruz
media@gastro.org
301-272-1603
American Gastroenterological Association
Source:Eurekalert

Related medicine news :

1. Obesity and diabetes double risk of HF -- patients with both conditions very difficult to treat
2. New Guidelines to Fight Obesity in Pregnancy Issued
3. University of Hawaii at Manoa professors co-author adolescent obesity study
4. Alliance for a Healthier Generation Applauds Sodexo for Their Pledge to Fight Childhood Obesity
5. Alliance for a Healthier Generation Applauds Sodexo for Their Pledge to Fight Childhood Obesity
6. Pennsylvania Secretaries of Health, Education Announce New Grant Initiatives to Curb Childhood Obesity, Boost Physical Activity in Schools
7. Sahlgrenska Academy to lead major European project on obesity
8. New direction needed for obesity research, Deakin health expert claims
9. Hispanic Cheese May Prevent Obesity
10. Productivity Takes a Hit From Obesity, Diabetes
11. Beverage Industry Fighting Childhood Obesity by Helping Children Balance Calories
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... (PRWEB) , ... June 27, 2016 , ... "FCPX editors ... customizable inside of Final Cut Pro X," said Christina Austin - CEO of Pixel ... style. Final Cut Pro X users can now reveal the media of ...
(Date:6/27/2016)... Brooklyn, NY (PRWEB) , ... June 27, 2016 ... ... is using cutting edge technology to revolutionize the emergency ambulance transport experience for ... Many are aware of how Uber has disrupted the taxi industry through the ...
(Date:6/26/2016)... ... 26, 2016 , ... On June 10-11, 2016, A Forever Recovery, a holistic ... World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. ... some of the world’s leading providers of cereal and other breakfast foods. Its residents ...
(Date:6/26/2016)... , ... June 26, 2016 , ... Brent Kasmer, a legally blind and certified personal ... personalized through a fitness app. The fitness app plans to fix the two major problems ... offer a one size fits all type program , They don’t eliminate all ...
(Date:6/25/2016)... TX (PRWEB) , ... June 25, 2016 , ... Austin ... of the American College of Mohs Surgery and to Dr. Russell Peckham for medical ... and highly effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Dehaier Medical Systems Ltd. (NASDAQ: ... and sells medical devices and wearable sleep respiratory products ... cooperation agreement with Hongyuan Supply Chain Management Co., Ltd. ... 20, 2016, to develop Dehaier,s new Internet medical technology ... will leverage Hongyuan Supply Chain,s sales platform to reach ...
(Date:6/24/2016)... DUBLIN , June 24, 2016 ... "The World Market for Companion Diagnostic Tests" report to ... World Market for Companion Diagnostics The World ... diagnostic and personalized medicine diagnostics. Market analysis in the report ... Diagnostics Test Market (In Vitro Diagnostic Kits) by Region (N. ...
(Date:6/24/2016)... , June 24, 2016   Pulmatrix, Inc ., ... developing innovative inhaled drugs, announced today that it was ... Investments reconstituted its comprehensive set of U.S. and ... "This is an important milestone for Pulmatrix," said Chief ... shareholder awareness of our progress in developing drugs for ...
Breaking Medicine Technology: