Navigation Links
Obesity may modify the association between alcohol consumption and the risk of colorectal cancer

A case-control study from Newfoundland/Labrador has reported that greater alcohol intake may increase the risk of colorectal cancer (CRC) among obese subjects, but not among non-obese subjects. This is not a particularly large study, and only 45-60% of subjects who were recruited by telephone ended up providing data. Further, it is a case-control comparison, rather than a cohort analysis, making bias in the results more likely.

In this study, there was no relation of alcohol with the risk of CRC when considering the entire population. However, when subjects were stratified by BMI (<30 versus = 30), the data indicate an increase in CRC risk for obese subjects who were "drinkers" (OR=2.2, 95% CI 1.2-4.0), especially among subjects reporting 5 or more drinks/daily (OR=3.7, CI 1.5-9.0). On the other hand, even among obese subjects there was not a clear dose-response effect noted, i.e., there was not a step-wise increase in CRC risk with greater number of drinks/day. For example, the odds ratio (OR) was 2.3 times that of non-drinkers for obese subjects reporting 1-2 drinks/daily and 1.3 for those reporting 3-4 drinks/daily.

It will be interesting to determine if other studies show that there is modification of the association between alcohol intake and colorectal cancer by obesity. If such is the case, it could help understand some of the mechanisms for the development of cancer and provide better guidelines for screening for CRC.


Contact: R. Curtis Ellison
Boston University Medical Center

Page: 1

Related medicine news :

1. Childhood obesity -- can faith-based organizations make a difference?
2. Parent-training intervention curbs pediatric obesity rates, study shows
3. Sanford-Burnham and Florida Hospital review obesity research progress with Takeda Pharmaceutical
4. Analyzing the causes of obesity in the Romani ethnic group
5. When Mom Has Pregnancy Diabetes, Breast-Feeding Curbs Child Obesity
6. Breastfeeding can reduce risk of childhood obesity
7. Positive parenting during early childhood may prevent obesity
8. Bariatric surgery in adolescents improves obesity-related diseases within first 2 years
9. Long Shifts May Raise Some Nurses Odds for Obesity
10. NIH grant targets inflammation in link between obesity and disease
11. Parents May Hold Key to Treating Kids Obesity
Post Your Comments:
(Date:6/27/2016)... CA (PRWEB) , ... June 27, 2016 , ... ... College District , the only authorized OSHA Training Institute Education Center headquartered in ... by protecting their workers from extreme heat at their worksites. Employers with ...
(Date:6/27/2016)... ... June 27, 2016 , ... "FCPX editors can now ... of Final Cut Pro X," said Christina Austin - CEO of Pixel Film Studios. ... Final Cut Pro X users can now reveal the media of their split ...
(Date:6/27/2016)... ... 2016 , ... TherapySites, the leading website and ... Tennessee Counseling Association. This new relationship allows TherapySites to continue to extend ... exclusive benefits and promotional offers. , "TCA is extremely excited about this new ...
(Date:6/27/2016)... ... June 27, 2016 , ... ePAY ... partnership with Connance, a healthcare industry leader providing predictive analytics to optimize ... combine to provide health systems, hospitals and ambulatory surgical centers with dramatic ...
(Date:6/27/2016)... ... June 27, 2016 , ... A revolution is underway. ... ambulance transport experience for the millions of people who require these medical transport ... taxi industry through the use of technology. Now, SmartEMS has put forth an ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... One of Australia,s successful biotechnology ... a new biotechnology company, Noxopharm Limited [ABN 50 608 966 123] ... to list on the ASX. Noxopharm is a clinic-ready ... a Phase 1 clinical study later this year. ... the biggest problems facing cancer patients - the ability of cancers ...
(Date:6/26/2016)... 2016 Jazz Pharmaceuticals plc (Nasdaq: ... Hart-Scott-Rodino Antitrust Improvements Act of 1976, as amended ("HSR"), ... Inc. ("Celator"; Nasdaq: CPXX ) expired effective ... As previously announced on May 31, 2016, ... agreement under which Jazz Pharmaceuticals has commenced a tender ...
(Date:6/26/2016)... , June 27, 2016  VMS Rehab Systems, Inc. ... will take whatever measures required to build a strong ... which is currently listed on the OTC Markets-pink current ... Chairman and CEO, "We are seeing an anomaly in ... understand, not only by the Company, but shareholders and ...
Breaking Medicine Technology: