Navigation Links
Obesity may modify the association between alcohol consumption and the risk of colorectal cancer
Date:2/23/2012

A case-control study from Newfoundland/Labrador has reported that greater alcohol intake may increase the risk of colorectal cancer (CRC) among obese subjects, but not among non-obese subjects. This is not a particularly large study, and only 45-60% of subjects who were recruited by telephone ended up providing data. Further, it is a case-control comparison, rather than a cohort analysis, making bias in the results more likely.

In this study, there was no relation of alcohol with the risk of CRC when considering the entire population. However, when subjects were stratified by BMI (<30 versus = 30), the data indicate an increase in CRC risk for obese subjects who were "drinkers" (OR=2.2, 95% CI 1.2-4.0), especially among subjects reporting 5 or more drinks/daily (OR=3.7, CI 1.5-9.0). On the other hand, even among obese subjects there was not a clear dose-response effect noted, i.e., there was not a step-wise increase in CRC risk with greater number of drinks/day. For example, the odds ratio (OR) was 2.3 times that of non-drinkers for obese subjects reporting 1-2 drinks/daily and 1.3 for those reporting 3-4 drinks/daily.

It will be interesting to determine if other studies show that there is modification of the association between alcohol intake and colorectal cancer by obesity. If such is the case, it could help understand some of the mechanisms for the development of cancer and provide better guidelines for screening for CRC.


'/>"/>

Contact: R. Curtis Ellison
ellison@bu.edu
Boston University Medical Center
Source:Eurekalert

Page: 1

Related medicine news :

1. Childhood obesity -- can faith-based organizations make a difference?
2. Parent-training intervention curbs pediatric obesity rates, study shows
3. Sanford-Burnham and Florida Hospital review obesity research progress with Takeda Pharmaceutical
4. Analyzing the causes of obesity in the Romani ethnic group
5. When Mom Has Pregnancy Diabetes, Breast-Feeding Curbs Child Obesity
6. Breastfeeding can reduce risk of childhood obesity
7. Positive parenting during early childhood may prevent obesity
8. Bariatric surgery in adolescents improves obesity-related diseases within first 2 years
9. Long Shifts May Raise Some Nurses Odds for Obesity
10. NIH grant targets inflammation in link between obesity and disease
11. Parents May Hold Key to Treating Kids Obesity
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Yisrayl Hawkins, ... week that explains one of the most popular and least understood books in the ... cryptic and puzzling descriptions that have baffled scholars for centuries. Many have tossed it ...
(Date:10/13/2017)... VA (PRWEB) , ... October 13, 2017 , ... ... of DevOps and Agile Software Development, has been awarded a contract by the ... Blanket Purchase Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies ...
(Date:10/13/2017)... ... ... On The Brink”: the Christian history of the United States and the loss of ... William Nowers. Captain Nowers and his wife, Millie, have six children, ten grandchildren, ... Navy. Following his career as a naval aviator and carrier pilot, he spent ...
(Date:10/12/2017)... ... 12, 2017 , ... CitiDent and San Francisco dentists, Dr. ... Oventus O2Vent technology. As many as 18 million Americans are estimated to suffer ... Oral appliances can offer significant relief to about 75 percent of people with ...
(Date:10/12/2017)... ... October 12, 2017 , ... The ... demand of today’s consumer and regulatory authorities worldwide. From Children’s to Adults 50+, ... to meet the highest standard. , These products are also: Gluten Free, ...
Breaking Medicine News(10 mins):
(Date:9/28/2017)... Sept. 28, 2017 Hill-Rom Holdings, Inc. (NYSE: ... conference call and webcast on Friday, November 3, 2017, ... and ending at approximately 8:30 a.m. (CDT) / 9:30 ... company,s 2017 financial performance and guidance for 2018, Hill-Rom ... to enhance operational performance, and long-range financial outlook through ...
(Date:9/25/2017)... , Sept. 25, 2017  EpiVax, Inc., ... vaccine design, and immune-engineering today announced the launch ... the development of personalized therapeutic cancer vaccines. EpiVax ... provided exclusive access to enabling technologies to the ... MBA will lead EpiVax Oncology as Chief Executive ...
(Date:9/19/2017)... 19, 2017   ZirMed Inc ., a recognized leader ... that it has been ranked #1 by its users for ... Rankings 2017 User Survey. ZirMed was recognized as the top-ranked ... and medical centers over 200 beds and holds one of ... user survey history. ...
Breaking Medicine Technology: