Navigation Links
Obesity linked to higher 5-year death rate after esophageal cancer surgery
Date:12/20/2011

ROCHESTER, Minn. -- Obesity doubles the risk of cancer recurrence and cancer-related death in patients with esophageal cancer who have been treated with surgery, researchers at Mayo Clinic found. Their 778-patient study, which appeared in the Dec. 1 issue of the Journal of Clinical Oncology (http://jco.ascopubs.org/), found that five-year survival in obese patients -- those with a body mass index of 30 or higher -- with esophageal cancer was 18 percent, compared to 36 percent in patients of normal weight.

VIDEO ALERT: Additional audio and video resources are available at the Mayo Clinic News Blog (http://newsblog.mayoclinic.org/2011/12/20/obesity-lowers-survival-chances-after-esophageal-cancer-surgery/).

The research is the first to find that obese patients with esophageal cancer have worse outcomes following surgery than patients with a normal weight, says lead investigator, Harry Yoon, M.D. (http://www.mayoclinic.org/bio/15120945.html), an oncologist at the Mayo Clinic Comprehensive Cancer Center (http://mayoresearch.mayo.edu/mayo/research/cancercenter/).

"Obesity is considered a risk factor in the development of this cancer, which is known to be both highly lethal and increasingly common," he says. "But prior to this study, we did not really understand the impact of obesity in this upper gastrointestinal cancer."

If validated in another study, the findings may change the way some physicians counsel obese patients with this disease Dr. Yoon says.

"As an oncologist, I did not typically speak to my patients about excess body weight as part of their care, because we are more often concerned about weight loss and maintaining proper nutrition, but that may change. It would be helpful to be able to offer patients some measures that they can take to possibly impact their prognosis," he says.

The study's findings applied to patients who had never smoked. Links between obesity and outcomes in smokers are more difficult to determine, because smoking is known to reduce weight and increase the likelihood of death. All the patients studied were treated at Mayo Clinic, and had undergone esophagectomy (removal of the esophagus), which is potentially curative.

Dr. Yoon says studies that have linked obesity with poor outcomes in other tumor types have proposed that excess weight produces a chronic inflammatory state, which can raise the risk of cancer development and worse outcomes.


'/>"/>
Contact: Joe Dangor
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Related medicine news :

1. Retired Military Brass Support First Ladys Call to Reduce Child Obesity, Improve Nutrition
2. NASBE Supports First Lady Michelle Obama in Fight Against Childhood Obesity
3. Childhood obesity: Its not the amount of TV, its the number of junk food commercials
4. Planting Seeds to Fight Childhood Obesity
5. PolicyLink CEO Angela Glover Blackwell Released the Following Statement on First Lady Michelle Obamas Childhood Obesity Initiative
6. AMA Joins First Lady in Fight Against Childhood Obesity
7. Soothing infants with food focus of childhood obesity study
8. In Support of the Lets Move Campaign to Fight Childhood Obesity, Verizon Thinkfinity Providing Free Educational Resources on Nutrition and Exercise
9. Explorers Bounty Puffed Fruit Snacks Helping Parents Battle Summer Obesity
10. The Alliance for a Healthier Generation Names Celtics Captain Paul Pierce National Athlete Spokesperson in the Fight Against Childhood Obesity
11. Tiny fruit fly could offer big clues in fight against obesity, researcher says
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/20/2017)... ... , ... Bionic Sports Nutrition LLC, an American company devoted to developing high-quality ... January ECRM Trade Show in Hilton Head, SC. , Bionic Sports Nutrition manufactures ... its products to all clients at reasonable prices. At the ECRM trade show, it ...
(Date:1/20/2017)... ... January 20, 2017 , ... ATP Science, ... everyday lives, recently attended the January ECRM Trade Show in Hilton Head, SC, ... for its large range of supplements that keep the body functioning at its ...
(Date:1/20/2017)... boca raton florida (PRWEB) , ... January 20, 2017 , ... ... trial at the Dana Farber Cancer Institute. For Betsy, the clinical trial has ... and her cancer has not worsened. , Betsy Brauser was diagnosed with ovarian ...
(Date:1/20/2017)... ... January 20, 2017 , ... Vitamin Well has launched ... The drinks have been produced in collaboration with Zlatan Ibrahimovic and have been ... , After a successful launch in Sweden last year, the next generation sports ...
(Date:1/20/2017)... ... 20, 2017 , ... “The Angel”: a heartwarming and earnest tale of ... of his children. “The Angel” is the creation of published author, Marjorie Lund-Fontaine, a ... and impassioned writer. , When asked of her new book, Marjorie says, “‘The Angel’ ...
Breaking Medicine News(10 mins):
(Date:1/21/2017)... Mass. , Jan. 20, 2017 /PRNewswire/ ... Keystone Symposia Conference, "PI3K Pathways in Immunology, ... Inc. (NASDAQ: INFI ) ... immuno-oncology development candidate that selectively inhibits phosphoinositide-3-kinase-gamma ... able to help overcome resistance to checkpoint ...
(Date:1/20/2017)... -- Research and Markets has announced the addition ... BMP, BUN Creatinine, Electrolyte Testing, HbA1c Testing, Comprehensive Metabolic Panel, Liver ... - 2024" report to their offering. ... The global clinical laboratory testing market ... Introduction of innovative solutions on the grounds of maximum efficiency and ...
(Date:1/20/2017)... 2017 Stock-Callers.com today evaluates the following ... ), Novo Nordisk A/S (NYSE: NVO ), Sucampo ... Holdings Inc. (NASDAQ: PTX ). These stocks belong ... th , 2017, finishing near its session lows. As per ... 0.7%, while shares of health care companies in the S&P ...
Breaking Medicine Technology: