Navigation Links
Obesity linked to higher 5-year death rate after esophageal cancer surgery
Date:12/20/2011

ROCHESTER, Minn. -- Obesity doubles the risk of cancer recurrence and cancer-related death in patients with esophageal cancer who have been treated with surgery, researchers at Mayo Clinic found. Their 778-patient study, which appeared in the Dec. 1 issue of the Journal of Clinical Oncology (http://jco.ascopubs.org/), found that five-year survival in obese patients -- those with a body mass index of 30 or higher -- with esophageal cancer was 18 percent, compared to 36 percent in patients of normal weight.

VIDEO ALERT: Additional audio and video resources are available at the Mayo Clinic News Blog (http://newsblog.mayoclinic.org/2011/12/20/obesity-lowers-survival-chances-after-esophageal-cancer-surgery/).

The research is the first to find that obese patients with esophageal cancer have worse outcomes following surgery than patients with a normal weight, says lead investigator, Harry Yoon, M.D. (http://www.mayoclinic.org/bio/15120945.html), an oncologist at the Mayo Clinic Comprehensive Cancer Center (http://mayoresearch.mayo.edu/mayo/research/cancercenter/).

"Obesity is considered a risk factor in the development of this cancer, which is known to be both highly lethal and increasingly common," he says. "But prior to this study, we did not really understand the impact of obesity in this upper gastrointestinal cancer."

If validated in another study, the findings may change the way some physicians counsel obese patients with this disease Dr. Yoon says.

"As an oncologist, I did not typically speak to my patients about excess body weight as part of their care, because we are more often concerned about weight loss and maintaining proper nutrition, but that may change. It would be helpful to be able to offer patients some measures that they can take to possibly impact their prognosis," he says.

The study's findings applied to patients who had never smoked. Links between obesity and outcomes in smokers are more difficult to determine, because smoking is known to reduce weight and increase the likelihood of death. All the patients studied were treated at Mayo Clinic, and had undergone esophagectomy (removal of the esophagus), which is potentially curative.

Dr. Yoon says studies that have linked obesity with poor outcomes in other tumor types have proposed that excess weight produces a chronic inflammatory state, which can raise the risk of cancer development and worse outcomes.


'/>"/>
Contact: Joe Dangor
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Related medicine news :

1. Retired Military Brass Support First Ladys Call to Reduce Child Obesity, Improve Nutrition
2. NASBE Supports First Lady Michelle Obama in Fight Against Childhood Obesity
3. Childhood obesity: Its not the amount of TV, its the number of junk food commercials
4. Planting Seeds to Fight Childhood Obesity
5. PolicyLink CEO Angela Glover Blackwell Released the Following Statement on First Lady Michelle Obamas Childhood Obesity Initiative
6. AMA Joins First Lady in Fight Against Childhood Obesity
7. Soothing infants with food focus of childhood obesity study
8. In Support of the Lets Move Campaign to Fight Childhood Obesity, Verizon Thinkfinity Providing Free Educational Resources on Nutrition and Exercise
9. Explorers Bounty Puffed Fruit Snacks Helping Parents Battle Summer Obesity
10. The Alliance for a Healthier Generation Names Celtics Captain Paul Pierce National Athlete Spokesperson in the Fight Against Childhood Obesity
11. Tiny fruit fly could offer big clues in fight against obesity, researcher says
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/26/2016)... ... May 26, 2016 , ... Saint Francis Hospital ... years, and the efforts have paid off. Since implementation of these efforts, ... care to enhance perioperative patient experiences and reduce costly complications. Since implementation in ...
(Date:5/26/2016)... ... May 26, 2016 , ... Development Team of Pixel ... for FCPX. , "This new layered style transition tool will keep a consistent flow ... CEO of Pixel Film Studios. , TranSweep is an all new layered style ...
(Date:5/26/2016)... (PRWEB) , ... May 26, 2016 , ... ... industry leader in Blood Pressure products . , High blood pressure affects ... effects. Left untreated, high blood pressure can lead to heart disease, stroke, kidney ...
(Date:5/25/2016)... ... May 26, 2016 , ... The United States Food and Drug Administration ... both men and women. To date, the company is the first and only manufacturer ... adult who suffers with androgenetic alopecia. , “This new level of clearance substantiates ...
(Date:5/25/2016)... ... 25, 2016 , ... The Georgia State University College of Law new building ... Design Commission. , The annual award recognizes projects, programs, individuals and organizations that have ... of its physical heritage and the balance between the old and the new. , ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... LONDON , May 24, 2016 ... erfüllt beide primären Endpunkte ... und Überlegenheit in ‚ausgezeichneter plus guter ... aufsteigenden Colons    ,      (Logo: ... B.V. gab heute neue positive Daten von der ...
(Date:5/24/2016)... -- NxStage Medical, Inc. (Nasdaq: NXTM ), a ... today announced that Jeffrey H. Burbank , Chief ... of investor conferences. Where applicable, a webcast of the ...   ... Friday, June 10, 2016 1:30 p.m. ET ...
(Date:5/24/2016)... HONG KONG , May 24, 2016 /PRNewswire/ ... primer stent de doble terapia del mundo, introduce ... fístula arteriovenosa. OrbusNeich, una compañía global ... cambian las vidas, ha expandido su cartera incluyendo ... catéteres balón JADE™ y Scoreflex™ PTA son los ...
Breaking Medicine Technology: