Navigation Links
Obesity-linked high blood volumes render PSA prostate cancer test less effective, study suggests
Date:11/20/2007

, M.D., Partins former postdoctoral fellow who is now an assistant professor at Duke University, investigated both ideas by assessing how much total PSA obese and normal-weight men have.

Using records of patients treated for prostate cancer between 1988 and 2006 at The Johns Hopkins Hospital, Duke University and various Veterans Affairs hospitals, Partin, Freedland and their colleagues compiled information on PSA concentration and body mass index (BMI), a ratio of body weight to height that generally indicates whether someone is underweight, normal weight or overweight.

Using a standard calculation, the researchers used BMIs to estimate the amount of blood circulating in each patients body. A different calculation used this blood volume, along with PSA concentrations, to estimate the total amount of PSA each patient had.

As expected, PSA concentrations were typically lower in the obese patients than in the normal-weight ones, although the total amount of PSA was about the same in both groups of patients.

Its clear to us that excess blood had diluted PSA concentrations in that group, says Partin.

Freedland says a variety of new tests currently in development for cancer and other diseases rely on the concentrations of disease markers similar to PSA circulating in the blood. For these other tests just starting down the development pipeline, he says, we need to think about the actual total amount of a biological marker rather than concentration.


'/>"/>

Contact: Christen Brownlee
cbrownlee@jhmi.edu
410-955-7832
Johns Hopkins Medical Institutions
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Specific antagonism lowers blood pressure
2. Restricting Blood Flow May Help Heart Bypass Patients
3. FDA Updates Prescription Guidelines for Blood Thinner
4. Doctors Often Miss High Blood Pressure in Kids
5. Back to School Means Return of School Blood Drives
6. Blood-flow detector software show promise in preventing brain damage
7. FDA Approves New Roche West Nile Virus Blood Screening Test
8. Australian-led international study shows blood pressure drugs cut death rate in type 2 diabetes
9. Laser blasts viruses in blood
10. Study Demonstrates Marteks Algal DHA Oil Improves Blood Triglyceride Lipid Levels
11. LifeMasters Provides Tips for Maintaining a Healthy Blood Cholesterol Level
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... 22, 2015 The City of West Hollywood hosted ... to commemorate the 42nd anniversary of the Supreme Court decision Roe ... been 42 years since the Roe vs. Wade decision and the ... present as ever,” said City of West Hollywood Councilmember Abbe Land. ...
(Date:1/22/2015)... The Incredible Bulk is a revolutionary method put together ... by up to 30lbs in less than 12 weeks without ... Stevenson, prompting an investigative review. , “Our Incredible Bulk ... formula that allows the body to pack on a massive ...
(Date:1/22/2015)... Orlando, Florida (PRWEB) January 22, 2015 ... up today at the 2015 PGA Merchandise Show to ... lady and incredible female amateur golfer, Arlene McKitrick. The ... career female amateur golf tournament win. She won her ...
(Date:1/22/2015)... January 22, 2015 Carinsurancesavings.biz has released a ... death and dismemberment insurance . , Purchasing an accidental ... be very advantageous. This type of rider provides benefits if ... can be considered a lesser form of life insurance. ...
(Date:1/22/2015)... Florida (PRWEB) January 22, 2015 IsoComforter, Inc. ... therapy machine with patented IsoTube design to treat specific body ... introduced the most progressive and easy to use patented cold ... post-operative and sports related orthopedic and muscle injuries. IsoComforter ...
Breaking Medicine News(10 mins):Health News:The Incredible Bulk: Review Examining Ben Pakulski’s Brand New Bulking Muscle Building Diet Program Released 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 3Health News:Accidental Death and Dismemberment Insurance Can Be Purchased at Low Prices Online 2Health News:IsoComforter Introduces Best of Class Cold Therapy Product to the Worldwide Market 2
... coronary artery stenosis, according to a large study performed ... , The study consisted of 1,331 patients who ... stenosis. 10,561 coronary artery segments were analyzed during the ... significant coronary artery stenosis in our patients; specificity was ...
... used a new imaging technique to take high quality ... in mice, and the technology could help in the ... may cause blindness. , The study, "The Clinical Time-Course ... with Histologic and Cellular Infiltrate Correlation," was published in ...
... Hopkins University has received a $4.97 million grant from ... initial phase of a unique program aimed at improving ... with the Johns Hopkins Center for Global Health, and ... Uganda. As part of the initiative, the faculties of ...
... OAKLAND, Calif., Dec. 1 As President Bush seeks,to ... which will especially,adversely impact healthcare services and workplace safety, ... new,website inviting web browsers to help "send Bush packing,", ... The site offers an interactive game highlighting some of ...
... Dec. 1 Mach One Corporation,(Pink Sheets: MNCN), a ... long term benefit to the agricultural and consumer,market, announced ... Board,of Directors effective upon the closing of the acquisition ... Mr. Ballantyne is ...
... For difficult to diagnose patients,Breast-Specific Gamma Imaging (BSGI) is ... ultrasound for patients who need additional imaging,following a questionable ... meeting of the Radiological Society of North America (RSNA).,BSGI ... lesions independent,of tissue density and discover very early stage ...
Cached Medicine News:Health News:New technique captures high-res images of full retina 2Health News:Johns Hopkins and Makerere University to collaborate on African health education initiative 2Health News:Johns Hopkins and Makerere University to collaborate on African health education initiative 3Health News:Citing 'Midnight Rules' to Erode Health and Safety, Nurses Unveil New Website to Send Bush Packing 2Health News:Mr. Tad Ballantyne to Join Mach One Board of Directors 2Health News:Molecular Breast Imaging Performs Better Than Ultrasound in Patients With Mammographic Abnormalities 2
(Date:1/23/2015)... plc (NYSE: MNK ) announced today that ... program. The open-ended authorization permits the company to repurchase ... "Funding additional initiatives and seeking attractive ... to pursue a range of focused growth strategies," said ...
(Date:1/22/2015)... 22, 2015  BiOptix is pleased to announce the appointment ... of Chemistry and Biochemistry. Scott joins the company after previous ... Amgen throughout the course of his nearly 20 year ... is a nationally recognized thought leader in the biosensor ...
(Date:1/22/2015)... Jan. 22, 2015  Bio-Techne Corporation (NASDAQ: TECH ... first member of the new Simple Plex platform through ... launch represents the re-branding of the previously acquired CyPlex ... platform is a transformative immunoassay technology which integrates an ...
Breaking Medicine Technology:Mallinckrodt plc Announces Share Repurchase Program 2Mallinckrodt plc Announces Share Repurchase Program 3Mallinckrodt plc Announces Share Repurchase Program 4BiOptix Expands Leadership Team with the Appointment of Dr. Scott Klakamp as Vice President of Chemistry and Biochemistry 2Bio-Techne Launches Simple Plex Platform 2Bio-Techne Launches Simple Plex Platform 3
... M1 is an advanced desktop PC ... is a sophisticated 2 channel stimulation ... electrical stimulations, 2 sound stimulations and ... You can customize each stimulation independently. ...
... high performance magnetic stimulator for use in both ... ,MagPro is able to stimulate with repetition rates ... field/nerve interface can be done using the ability ... direction. , , , , ,MagPro is ...
... X-SIZER System is a ... for thrombus removal in ... saphenous vein grafts. ... cutter and,continuous evacuation. ...
... Allura Xper is the perfect partner for ... these systems are scalable to meet your ... come.,Flexibility means that your Allura Xper FD20 ... cardiac use. Openness to new technologies allows ...
Medicine Products: