Navigation Links
Obesity-induced fatty liver disease reversed in mice
Date:1/29/2014

activating AMPK. To test this theory, they added four chemically modified versions of the drug to the cells and found that the derivatives were able to activate AMPK without valproic acid. In fact, they achieved higher activation of AMPK at one-fortieth the concentration.

To assess the uptake and breakdown of valproic acid in living organisms, they gave the drug to obese mice with high blood sugar levels, fatty livers and rapid weight gain. Treated mice showed decreased blood sugar levels, decreases in the size and the fat accumulation of their livers, and a stabilization of weight rather than the continued weight gain experienced by untreated mice.

"The improvements seen in the health of these obese mice were very encouraging," says Bumpus. "We hope that we will find similar results in obese people who take valproic acid."


'/>"/>

Contact: Catherine Kolf
ckolf@jhmi.edu
443-287-2251
Johns Hopkins Medicine
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Fatty acid found in fish prevents age-related vision loss: U of A medical research
2. Pictures of Fatty, Sugary Foods May Spur Cravings
3. Girls with eating disorders regain healthy fatty acid levels when their weight normalizes
4. Analysis of conflicting fish oil studies finds that omega-3 fatty acids still matter
5. Scripps Florida scientists develop new compound that reverses fatty liver disease
6. Limiting polyunsaturated fatty acid levels in pregnancy may influence body fat of children
7. Fatty Liver Treatment
8. How “Fatty Liver Diet Guide” Helps People Treat Fatty Liver Quickly – Vkool.com
9. Omega-3 fatty acids more effective at inhibiting growth of triple-negative breast cancer
10. Scarring May Raise Death Risk From Fatty Liver Disease
11. Gene variant ID could lead to better fatty liver disease diagnosis
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Obesity-induced fatty liver disease reversed in mice
(Date:9/1/2015)... , ... September 01, 2015 , ... ... availability of the newly updated International Audit Protocol Consortium (IAPC) EHS audit protocol ... protocols to understand the scope of their EHS regulatory obligations and rapidly collect, ...
(Date:8/31/2015)... ... September 01, 2015 , ... ... the release of ten hours of new premium on-demand video Evidence Based ... , Athletic Trainers certified before 2014 must complete 50 CEUs before December 31, ...
(Date:8/31/2015)... ... 31, 2015 , ... Jvion, the Atlanta-based leader in predictive ... focused on helping hospital perform under the Center for Medicare & Medicaid Services’ ... based on performance across four domains related to care quality. To receive a ...
(Date:8/31/2015)... ... August 31, 2015 , ... ... a wealth of information for specific translation services within the medical and pharmaceutical ... incredible track record of successful work. , ITC Global Translations specializes in professional ...
(Date:8/31/2015)... ... , ... When it comes to undergoing a hair transplant, most patients have donor hair moved ... volume to the hair on top of the scalp, as well as filling in areas ... donor hair on other areas of their head. , What about patients who have a ...
Breaking Medicine News(10 mins):Health News:Specialty Technical Publishers (STP) and Specialty Technical Consultants(STC) Publish Environmental, Health & Safety (EHS) Audit Protocol for the European Union 2Health News:Specialty Technical Publishers (STP) and Specialty Technical Consultants(STC) Publish Environmental, Health & Safety (EHS) Audit Protocol for the European Union 3Health News:Specialty Technical Publishers (STP) and Specialty Technical Consultants(STC) Publish Environmental, Health & Safety (EHS) Audit Protocol for the European Union 4Health News:Evidence Based Practice Courses: CEUs For Athletic Trainers Just Released 2Health News:Jvion Releases Value-Based Purchasing Predictive Use Case 2Health News:GoMarketing Announces Major Updates to ITC Global Translations Website http://www.ITCGlobalTranslations.com 2Health News:GoMarketing Announces Major Updates to ITC Global Translations Website http://www.ITCGlobalTranslations.com 3Health News:Body Hair Transplants to Help Achieve a Full Head of Hair 2
... report on asthma and exercises says, for people with ... non-specific upper body exercises, will make people to use ... journal Thorax focuses that breathing techniques are the most ... such as albuterol, is the reliever used by many ...
... Naik, sentenced to a month's imprisonment last ... contempt case, today underwent an angiography at ... the government's JJ Hospital, where Naik was ... of chest pain, said he underwent the ...
... the surgery done for obesity. This type of surgery is ... its population is estimated to be overweight.// Bariatric Surgery in ... country., ,A private hospital in Calcutta today launched a ... from severe obesity, a disease that is fast attaining epidemic ...
... green leafy vegetables such as kale, spinach and collard ... ,These vegetables are known to contain a variety ... include lutein, vitamins C and E, flavonoids, folic acid, ... ,Researchers studied over 1,000 adults living in Australia ...
... says, in people with mild asthma, breathing techniques and ... dose of preventer inhaler//. ,The researchers ... lung function, use of medication and quality of life ... technique focused on shallow, nasal breathing with slow exhalations, ...
... led to the identification of a starter hormone responsible ... ,The research was led by David Champlin, a ... assisted by students Paul Allee of Portland and Steven ... at the University of Washington and Hirosaki University in ...
Cached Medicine News:Health News:Bariatric Surgery Solution to Obesity and to Boost Medical Tourism 2Health News:Skin Cancer Risk Reduced by Taking Green Leafy Vegetables 2Health News:Hormone Transforming Caterpillars to Moths Identified 2
(Date:8/31/2015)... Pa. , Aug. 31, 2015  The departments ... an event today at Gaudenzia Concept 90 to raise ... drug overdose crisis in Pennsylvania ... treatment and focus on recovery through the Building ... many Pennsylvanians are dying every day to a disease ...
(Date:8/31/2015)... MOUNTAIN VIEW, Calif. , Aug. 31, 2015 ... SAN) and the life sciences team at Google announced ... outcomes for people with type 1 and type 2 ... devices with Google,s expertise in analytics, miniaturized electronics and ... to improve diabetes care by developing new tools that ...
(Date:8/31/2015)... Calif. , Aug. 31, 2015  Asterias ... focused on the emerging field of regenerative medicine, ... dosed at Chicago -based Rush ... trial evaluating activity of escalating doses of AST-OPC1 ... sensory and motor complete cervical spinal cord injury ...
Breaking Medicine Technology:Pennsylvania Departments of Drug & Alcohol Programs and Health Kick-off Second Annual Building Bridges to Recovery Initiative 2Sanofi to Collaborate with Google Life Sciences to Improve Diabetes Health Outcomes 2Sanofi to Collaborate with Google Life Sciences to Improve Diabetes Health Outcomes 3Sanofi to Collaborate with Google Life Sciences to Improve Diabetes Health Outcomes 4Sanofi to Collaborate with Google Life Sciences to Improve Diabetes Health Outcomes 5Sanofi to Collaborate with Google Life Sciences to Improve Diabetes Health Outcomes 6Asterias Biotherapeutics Concludes Recruitment of Initial Safety Cohort of the SCiStar Phase 1/2a Dose-Escalation Clinical Trial of AST-OPC1 for Complete Cervical Spinal Cord Injury 2Asterias Biotherapeutics Concludes Recruitment of Initial Safety Cohort of the SCiStar Phase 1/2a Dose-Escalation Clinical Trial of AST-OPC1 for Complete Cervical Spinal Cord Injury 3Asterias Biotherapeutics Concludes Recruitment of Initial Safety Cohort of the SCiStar Phase 1/2a Dose-Escalation Clinical Trial of AST-OPC1 for Complete Cervical Spinal Cord Injury 4Asterias Biotherapeutics Concludes Recruitment of Initial Safety Cohort of the SCiStar Phase 1/2a Dose-Escalation Clinical Trial of AST-OPC1 for Complete Cervical Spinal Cord Injury 5Asterias Biotherapeutics Concludes Recruitment of Initial Safety Cohort of the SCiStar Phase 1/2a Dose-Escalation Clinical Trial of AST-OPC1 for Complete Cervical Spinal Cord Injury 6
... Masimo (Nasdaq: MASI ) announced ... Welfare (MHLW) regulatory clearance of its noninvasive and ... the Masimo rainbow SET® platform.  Representing a breakthrough ... hemoglobin level in real-time, SpHb tracks and trends ...
... As US doctors consider the switch from paper charts to ... have teamed up to provide an absolutely free EMR ... only ad-supported EMR platform for medical providers in a sector ... for a five provider practice in the first year. Since ...
Cached Medicine Technology:Masimo Noninvasive and Continuous Hemoglobin Receives Market Clearance in Japan 2Masimo Noninvasive and Continuous Hemoglobin Receives Market Clearance in Japan 3Masimo Noninvasive and Continuous Hemoglobin Receives Market Clearance in Japan 4Can an Ad-Supported EMR Fuel Healthcare's Technology Revolution? 2Can an Ad-Supported EMR Fuel Healthcare's Technology Revolution? 3Can an Ad-Supported EMR Fuel Healthcare's Technology Revolution? 4
Hemagglutination slide test for the qualitative and quantitative detection of Rheumatoid Factor in serum or synovial fluid....
Hemagglutination slide test for the differential qualitative detection and quantitative determination of infectious mononucleosis and other heterophile antibodies in serum or plasma....
Color-enhanced hemagglutination slide test for the rapid qualitative and semi-quantitative detection of infectious mononucleosis heterophile antibodies in serum or plasma....
... Inverness Medical Professional Diagnostics is a leading ... IFA and DFA test menu that includes ... STDs as well as miscellaneous conjugates and ... you a wide assortment of substrates and ...
Medicine Products: