Navigation Links
Obesity in type 2 diabetes: Recommendations from guidelines are largely consistent
Date:7/30/2012

On 10th July 2012, the German Institute for Quality and Efficiency in Health Care (IQWiG) published the results of a literature search for evidence-based guidelines for the treatment of obesity in type 2 diabetes. The aim of the report was to identify those recommendations from current guidelines of high methodological quality that may be relevant for a possible new obesity module in the disease management programme (DMP) for type 2 diabetes.

Diet, exercise and behavioural therapy generally advised

IQWiG found that the recommendations of the various guidelines for the treatment of people with type 2 diabetes who are also grossly overweight were more or less consistent: in general, alongside weight reduction, diet, exercise and behavioural therapy were also advised. Above a certain Body Mass Index (BMI), some guidelines also mention drugs to aid weight reduction (BMI ≥ 27 kg/m) or surgery - for example a gastric bypass (BMI ≥ 35 kg/m) - as a treatment option. However, the strength of the recommendation, i.e. whether the particular intervention "could", "should" or "must" be used, varies between the individual guidelines. The level of evidence, i.e. the extent to which the recommendations are backed up by results from studies, also differs.

Systematic reviews do not report patient-relevant outcomes

In accordance with the commission received from the Federal Joint Committee (G-BA), the Institute searched for and evaluated systematic reviews, as well as guidelines. The aim was to compare the recommendations of the guidelines with the conclusions of the reviews, i.e. the scientific evidence from studies. However, IQWiG was unable to identify any reviews that were based on the results of studies of high methodological quality and summarized the relevant results for the treatment of people who suffered from both type 2 diabetes and obesity.

Furthermore, the systematic reviews reported largely metabolic parameters, but no patient-relevant outcomes such as blindness or amputation. This means that the conclusions in the guidelines are, for the most part, not supported by evidence from systematic reviews.

Procedure of report production

IQWiG published the preliminary results in the form of the preliminary report in October 2011 and interested parties were invited to submit comments. When the commenting procedure ended, the preliminary report was revised and sent as a final report to the contracting agency, the Federal Joint Committee, in May 2012. The written comments are published in a separate document at the same time as the final report. The report was produced in collaboration with external experts.

On 10th July 2012, the German Institute for Quality and Efficiency in Health Care (IQWiG) published the results of a literature search for evidence-based guidelines for the treatment of obesity in type 2 diabetes. The aim of the report was to identify those recommendations from current guidelines of high methodological quality that may be relevant for a possible new obesity module in the disease management programme (DMP) for type 2 diabetes.

Diet, exercise and behavioural therapy generally advised

IQWiG found that the recommendations of the various guidelines for the treatment of people with type 2 diabetes who are also grossly overweight were more or less consistent: in general, alongside weight reduction, diet, exercise and behavioural therapy were also advised. Above a certain Body Mass Index (BMI), some guidelines also mention drugs to aid weight reduction (BMI ≥ 27 kg/m) or surgery - for example a gastric bypass (BMI ≥ 35 kg/m) - as a treatment option. However, the strength of the recommendation, i.e. whether the particular intervention "could", "should" or "must" be used, varies between the individual guidelines. The level of evidence, i.e. the extent to which the recommendations are backed up by results from studies, also differs.

Systematic reviews do not report patient-relevant outcomes

In accordance with the commission received from the Federal Joint Committee (G-BA), the Institute searched for and evaluated systematic reviews, as well as guidelines. The aim was to compare the recommendations of the guidelines with the conclusions of the reviews, i.e. the scientific evidence from studies. However, IQWiG was unable to identify any reviews that were based on the results of studies of high methodological quality and summarized the relevant results for the treatment of people who suffered from both type 2 diabetes and obesity.

Furthermore, the systematic reviews reported largely metabolic parameters, but no patient-relevant outcomes such as blindness or amputation. This means that the conclusions in the guidelines are, for the most part, not supported by evidence from systematic reviews.

Procedure of report production

IQWiG published the preliminary results in the form of the preliminary report in October 2011 and interested parties were invited to submit comments. When the commenting procedure ended, the preliminary report was revised and sent as a final report to the contracting agency, the Federal Joint Committee, in May 2012. The written comments are published in a separate document at the same time as the final report. The report was produced in collaboration with external experts.


'/>"/>
Contact: Dr. Anna-Sabine Ernst
presse@iqwig.de
49-022-135-6850
Institute for Quality and Efficiency in Health Care
Source:Eurekalert

Related medicine news :

1. In-utero exposure to magnetic fields associated with increased risk of obesity in childhood
2. High blood sugar, obesity increase risk for surgical site infection
3. Tel Aviv University research links childhood obesity to cancer risk
4. In utero exposure to diesel exhaust a possible risk factor for obesity
5. 2 New Weight-Loss Drugs Wont Reverse U.S. Obesity Crisis
6. Fighting obesity with thermal imaging
7. Obesity may affect response to breast cancer treatment
8. Obesity Might Hinder Treatment of Some Breast Cancers
9. Obesity Alone May Not Hurt Kids Classroom Performance
10. New evidence for link between obesity and circle of friends
11. Vanderbilt study finds obesity linked to kidney injury after heart surgery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX ... Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s package transforms over ... Cut Pro X . Simply select a ProHand generator and drag it above media ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits of moderation, ... the latter, setting the bar too high can result in disappointment, perhaps even self-loathing. ... toward their goal. , Research from PsychTests.com reveals that behind the ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Pulmonary Hypertension Association ... it will receive two significant new grants to support its work to advance ... 25th anniversary by recognizing patients, medical professionals and scientists for their work in ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening their pencils ... an essay contest in which patients and their families pay tribute to a genetic ... 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. ...
(Date:6/24/2016)... , ... June 24, 2016 , ... National recruitment firm ... life sciences executive with extensive sequencing and genomics experience, as Vice President of North ... Ms. Hill will be responsible for leading the sales team in the commercialization of ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 Dehaier Medical Systems ... "Company"), which develops, markets and sells medical devices and ... , signed a strategic cooperation agreement with Hongyuan Supply ... Supply Chain") on June 20, 2016, to develop Dehaier,s ... strategic cooperation agreement, Dehaier will leverage Hongyuan Supply Chain,s ...
(Date:6/24/2016)... , June 24, 2016   Pulmatrix, Inc ., ... developing innovative inhaled drugs, announced today that it was ... Investments reconstituted its comprehensive set of U.S. and ... "This is an important milestone for Pulmatrix," said Chief ... shareholder awareness of our progress in developing drugs for ...
(Date:6/23/2016)... Research and Markets has announced the addition of ... report to their offering. ... kidney failure, it replaces the function of kidneys by removing ... thus the treatment helps to keep the patient body,s electrolytes ... Increasing number of ESRD patients & substantial healthcare expenditure ...
Breaking Medicine Technology: