Navigation Links
Obesity in men could dictate future colon screenings
Date:2/4/2014

Obesity is a known risk factor for many cancers including colon cancer, yet the reasons behind the colon cancer link have often remained unclear.

A Michigan State University study is shedding more light on the topic and has shown that elevated leptin a fat hormone higher body mass index and a larger waistline in men is associated with a greater likelihood of having colorectal polyps, precancerous growths linked to colon cancer.

The result may put men at an even greater risk of the disease and also may mean their body weight could eventually be a deciding factor in whether a colonoscopy is in their future. Today, age and family history typically dictate a screening.

Jenifer Fenton, assistant professor and researcher in the Department of Food Science and Human Nutrition, and Kari Hortos, associate dean in MSU's College of Osteopathic Medicine at the Macomb University Center, led the 18-month, cross-sectional study, which followed 126 healthy, white American males ranging from 48 to 65 years of age. Participants showed no signs or symptoms of health issues, yet underwent routine colonoscopies.

"What we found is 78 percent of the 126 men in the study were either overweight or obese based on their BMI or waist circumference. Of those, about 30 percent were found to have more than one polyp after colonoscopies were performed," said Fenton. "In fact, the more obese participants were 6.5 times more likely to have three polyps compared to their thinner counterparts."

Sarah Comstock, a co-author of the study and research fellow in the Department of Food Science and Human Nutrition, also indicated that the significance of the research is twofold.

"Not only does it show the association that leptin and a higher BMI have with colon polyps, but it gives us a better snapshot on how body weight and other factors may actually help us determine who might be at a higher risk of developing polyps," she said.

With obesity rates climbing during the past 20 years within the United States and colon cancer being the second-leading killer of men and women in the nation, these facts compelled Fenton and her team to conduct research which could identify the specific biomarkers of obesity and early-stage colon cancer and help in prevention efforts.

Previous research published by Fenton in 2009 identified the connection between obesity and colon cancer through examining tissue hormones. These studies demonstrated that, at higher levels, leptin worked as a primary mechanism in inducing precancerous colon cells by increasing the blood supply to them and promoting their progression.

"Even with all of our research, there's still more to be done, particularly in larger, more diverse populations, before any changes in screening recommendations can be made," said Fenton. "But we've definitely got a good start."

The study was recently published in the online journal PLOS ONE.


'/>"/>

Contact: Sarina Gleason
sarina.gleason@cabs.msu.edu
517-355-9742
Michigan State University
Source:Eurekalert  

Related medicine news :

1. Tighter economic regulation needed to reverse obesity epidemic -- study
2. Could you relationship with your mom increase your childs chances of obesity?
3. Obesity-induced fatty liver disease reversed in mice
4. Labeling obesity as a disease may have psychological costs
5. Better eating habits, not bad economy, stabilized obesity rates
6. Whos to blame for obesity? Policymakers, the food industry, or individuals?
7. Obesity Solutions Mexico Directed by Dr. Jose A. Castaneda Awarded 2013's Best Bariatric Surgeon by allPrivateHealth.com
8. Passing bowls family-style teaches day-care kids to respond to hunger cues, fights obesity
9. Family Voices Awarded Project to Fight Childhood Obesity by the Patient-Centered Outcomes Research Institute
10. Protein links liver cancer with obesity, alcoholism, and hepatitis
11. UCSF research finds new link between obesity, early decline in kidney function
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Obesity in men could dictate future colon screenings
(Date:6/26/2016)... Michigan (PRWEB) , ... June 26, 2016 , ... On ... as sponsor of the 2016 Cereal Festival and World’s Longest Breakfast Table in Battle ... honor of the city’s history as home to some of the world’s leading providers ...
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet ... product that was developed to enhance the health of felines. The formula is all-natural ... two main herbs in the PawPaws Cat Kidney Support Supplement Soft Chews ...
(Date:6/26/2016)... Orion, Clarkston, Michigan (PRWEB) , ... June 26, ... ... with respect to fertility once they have been diagnosed with endometriosis. These women ... intercourse but they also require a comprehensive approach that can help for preservation ...
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery services, can now ... and to Dr. Russell Peckham for medical and surgical dermatology. , Dr. Dorsey brings ... The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was under the ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand ... project," said Christina Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s ... within Final Cut Pro X . Simply select a ProHand generator and drag ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... -- Research and Markets has announced ... Applications, Technologies, Forecasts" report to their offering. ... Smart Skin, Structural Health Monitoring, Composite Smart Structures, ... involves electronic and/or electrical components and circuits that ... such as vehicle bodies or conformally placed upon ...
(Date:6/24/2016)... India , June 24, 2016 ... Needles Market by Type (Standard Pen Needles, Safety Pen ... Therapy (Insulin, GLP-1, Growth Hormone), Mode of Purchase (Retail, ... by MarketsandMarkets, This report studies the market for the ... expected to reach USD 2.81 Billion by 2021 from ...
(Date:6/23/2016)... 2016 Research and Markets has announced ... Forecast to 2022" report to their offering. ... the patients with kidney failure, it replaces the function of ... patient,s blood and thus the treatment helps to keep the ... balance. Increasing number of ESRD patients & ...
Breaking Medicine Technology: