Navigation Links
Obesity in men could dictate future colon screenings
Date:2/4/2014

Obesity is a known risk factor for many cancers including colon cancer, yet the reasons behind the colon cancer link have often remained unclear.

A Michigan State University study is shedding more light on the topic and has shown that elevated leptin a fat hormone higher body mass index and a larger waistline in men is associated with a greater likelihood of having colorectal polyps, precancerous growths linked to colon cancer.

The result may put men at an even greater risk of the disease and also may mean their body weight could eventually be a deciding factor in whether a colonoscopy is in their future. Today, age and family history typically dictate a screening.

Jenifer Fenton, assistant professor and researcher in the Department of Food Science and Human Nutrition, and Kari Hortos, associate dean in MSU's College of Osteopathic Medicine at the Macomb University Center, led the 18-month, cross-sectional study, which followed 126 healthy, white American males ranging from 48 to 65 years of age. Participants showed no signs or symptoms of health issues, yet underwent routine colonoscopies.

"What we found is 78 percent of the 126 men in the study were either overweight or obese based on their BMI or waist circumference. Of those, about 30 percent were found to have more than one polyp after colonoscopies were performed," said Fenton. "In fact, the more obese participants were 6.5 times more likely to have three polyps compared to their thinner counterparts."

Sarah Comstock, a co-author of the study and research fellow in the Department of Food Science and Human Nutrition, also indicated that the significance of the research is twofold.

"Not only does it show the association that leptin and a higher BMI have with colon polyps, but it gives us a better snapshot on how body weight and other factors may actually help us determine who might be at a higher risk of developing polyps," she said.

With obesity rates climbing during the past 20 years within the United States and colon cancer being the second-leading killer of men and women in the nation, these facts compelled Fenton and her team to conduct research which could identify the specific biomarkers of obesity and early-stage colon cancer and help in prevention efforts.

Previous research published by Fenton in 2009 identified the connection between obesity and colon cancer through examining tissue hormones. These studies demonstrated that, at higher levels, leptin worked as a primary mechanism in inducing precancerous colon cells by increasing the blood supply to them and promoting their progression.

"Even with all of our research, there's still more to be done, particularly in larger, more diverse populations, before any changes in screening recommendations can be made," said Fenton. "But we've definitely got a good start."

The study was recently published in the online journal PLOS ONE.


'/>"/>

Contact: Sarina Gleason
sarina.gleason@cabs.msu.edu
517-355-9742
Michigan State University
Source:Eurekalert  

Related medicine news :

1. Tighter economic regulation needed to reverse obesity epidemic -- study
2. Could you relationship with your mom increase your childs chances of obesity?
3. Obesity-induced fatty liver disease reversed in mice
4. Labeling obesity as a disease may have psychological costs
5. Better eating habits, not bad economy, stabilized obesity rates
6. Whos to blame for obesity? Policymakers, the food industry, or individuals?
7. Obesity Solutions Mexico Directed by Dr. Jose A. Castaneda Awarded 2013's Best Bariatric Surgeon by allPrivateHealth.com
8. Passing bowls family-style teaches day-care kids to respond to hunger cues, fights obesity
9. Family Voices Awarded Project to Fight Childhood Obesity by the Patient-Centered Outcomes Research Institute
10. Protein links liver cancer with obesity, alcoholism, and hepatitis
11. UCSF research finds new link between obesity, early decline in kidney function
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Obesity in men could dictate future colon screenings
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Apple ... care services, staged a mock evacuation of the facility as part of a disaster ... Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well as the ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Global Healthcare Management’s ... Alexandria Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s ... The fun run is geared towards children of all ages; it is a ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the ... danger possible to save lost souls in the Philippines. “The Journey: From the Mountains ... a dedicated teacher of the Bible. She has taught all ages and currently teaches ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and ... plans to open a flagship location in Covington, LA at 401 N. U.S. Highway ... store next to Office Depot in the Holiday Square shopping center. Its location allows ...
(Date:10/12/2017)... ... 2017 , ... Asante, a nationally recognized health system in ... existing home health joint venture through an agreement, effective October 1, 2017, to ... home health company with Asante, delivering clinically integrated care, for the past eight ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... -- NDS received FDA 510(k) clearance in May 2017 for its highly ... designed for endoscopy environments. An innovative secondary monitor solution, ZeroWire ... support the improvement of patient outcomes, procedural efficiency, and the lowering ... ... ...
(Date:10/4/2017)... 4, 2017  South Korean-based healthcare product Development Company ... "cprCUBE" on Kickstarter. The device will educate the user ... with better efficiency compared to the dated and pricey ... on efficacy of the compression for a more informed ... goal to raise $5,000. ...
(Date:10/2/2017)... 2017  Eli Lilly and Company (NYSE: ... third quarter of 2017 on Tuesday, October 24, 2017. ... day with the investment community and media to further ... call will begin at 9 a.m. Eastern time. Investors, ... webcast of the conference call through a link that ...
Breaking Medicine Technology: