Navigation Links
Obesity and metabolism: Weight gain and the growing risk of cancer
Date:12/7/2007

ancer, the reasons have been unclear. By evaluating prostate cancer data from a large, long-term cohort study, researchers at Johns Hopkins University have shown that those with high concentrations of C-peptide a marker of high insulin secretion that is a hallmark of diabetes had a measurable decrease in prostate cancer risk.

Metabolic perturbations influence cancer risk, that much is becoming clear to us, and we are learning more about the fundamental issues in biology that guide prostate cancer development, said Gabriel Lai, a doctoral student in the Department of Epidemiology at Johns Hopkins Bloomberg School of Public Health. One interesting possibility is that, over time, diabetics generally have less testosterone in their bloodstream than non-diabetics, which might lower risk of prostate cancer.

Lai and his colleagues used data from a large-scale study known as CLUE II, which had enrolled almost 23,000 adults in Washington County, Maryland in 1989. With funding from the National Cancer Institute, they examined the history of 264 men with confirmed prostate cancer and matched them with a group of 264 men without prostate cancer with a similar distribution of age and race.

For each participant, the researchers measured the amount of C-peptide in the blood they donated when they enrolled in the study. Researchers consider C-peptide to be a surrogate marker for insulin secretion because both molecules derive from the same precursor molecule, with insulin degrading faster than C-peptide. They found that patients that had elevated levels of C-peptide in their bloodstream when they started the study were about one-third less likely to develop prostate cancer later. This was true even among men without diabetes.

The researchers also report a markedly lower risk of non-metastasized prostate cancer. Men with higher C-peptide levels in their blood were half as likely to develop organ-confined prostate cancer, Lai says.

Ev
'/>"/>

Contact: Greg Lester
greg.lester@aacr.org
267-646-0554
American Association for Cancer Research
Source:Eurekalert

Page: 1 2 3 4 5 6 7

Related medicine news :

1. Virus Could Help Drive Obesity
2. Surgery for severe obesity saves lives
3. Obesity Doesnt Always Equal Diabetes
4. Obesity Rate in U.S. Still Climbing
5. Treating diabetes during pregnancy can break link to childhood obesity
6. ZIP codes and property values predict obesity rates
7. High and mighty: first common height gene identified by researchers behind obesity gene finding
8. Research Links TV/Video Game Playing With Child Obesity; Health Experts Back a New Approach
9. This October, the American Physical Therapy Associations National Physical Therapy Month to Focus on Nations Obesity Epidemic
10. UT Southwesterns obesity research receives $22 million NIH Roadmap grant
11. Genaera Announces Formation of Scientific Advisory Board for Obesity Drug Candidate Trodusquemine (MSI-1436)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/18/2015)... April 18, 2015 Carinsurancequotesinfo.com has released ... can cover physical injuries caused by a car ... financial coverage for a vehicle. A policy can pay ... an accident. Drivers should always carry appropriate coverage when ... policy can be bought with several important riders that ...
(Date:4/18/2015)... (PRWEB) April 18, 2015 "I recognized ... stretchers in healthcare facilities," said an inventor from Cincinnati, ... storage system." , He developed the Slyde Door to ... used in healthcare facilities. It provides convenient storage space ... are more stretchers available for patients. , This ...
(Date:4/18/2015)... Insuranceautoquote.info has released a new blog post explaining ... , Clients can review important auto insurance quotes ... provides important advantages for clients who need affordable financial ... not have coverage for their vehicles can purchase a ... hour. Many agencies offer important discounts and drivers can ...
(Date:4/18/2015)... (PRWEB) April 18, 2015 Patients who ... of developing mesothelioma later in life, but the disease ... mesothelioma that is unrelated to radiation. Surviving Mesothelioma has ... its website. Click here to read it now. ... compared the cases of 45 patients who had both ...
(Date:4/18/2015)... More than 2000 styles of newly ... the #1 online store carrying celebrity inspired special occasion ... got their perfect dresses for their prom. For those ... dresses at TheCelebrityDresses.com would be an ideal choice. ... prom dresses inspired by the most loved styles seen ...
Breaking Medicine News(10 mins):Health News:Auto Insurance Plans Can Cover Physical Injuries Caused By An Accident! 2Health News:Clients Can Review Car Insurance Quotes Online To Find Low Cost Offers! 2Health News:New Study Examines Relationship Between Radiation for Hematologic Cancers and Development of Mesothelioma, According to Surviving Mesothelioma 2Health News:Prom Dresses 2015 on Sale at TheCelebrityDresses.com 2
... 2, 2008 Rochester,Medical Corporation (Nasdaq: ROCM ... now allows intermittent catheter users to benefit from,not ... 2008, the four regional Durable Medical Equipment,(DME) Medicare ... a new reimbursement policy covering the use of,Intermittent ...
... is being released by the National Association of Boards ... and convenient when,patients use legitimate online pharmacies, but it ... recipients of counterfeit drugs from,dishonest Web sites. The vast ... "buyer beware" situations as it is often difficult,for them ...
... ... Heroes, FORT WORTH, Texas, ... flight attendants who,have administered emergency medical attention by using onboard,defibrillators. Flight attendants ... to celebrate the lives saved and heroic,measures taken during medical emergencies inflight ...
... cancer incidence not clear yet, expert says , , WEDNESDAY, ... on chromosome 15 that has three nicotine receptor genes that ... finding offers yet more evidence that lung cancer is tied ... variants represent a direct risk for lung cancer and ...
... Mo., April 2, 2008 As the use ... threatened,with greater liability for loss associated with unauthorized ... Stuckey & Company gives critical,professional liability options that ... Their technology insurance program can give,both 1st and ...
... A substantial,proportion of the nation,s public school ... school students, some possibly going beyond,sanctions set by ... led by the,Pacific Institute for Research and Evaluation ... sports and extracurricular activities., The study, funded ...
Cached Medicine News:Health News:Rochester Medical Applauds Improved U.S. Medicare Coverage Policy for Intermittent Catheters 2Health News:Indiana Adopts Legislation to Combat Illegitimate Online Pharmacies, Protect Residents From Counterfeit Drugs 2Health News:Indiana Adopts Legislation to Combat Illegitimate Online Pharmacies, Protect Residents From Counterfeit Drugs 3Health News:American Airlines Honors Flight Attendants at Golden Heart Awards Ceremony 2Health News:Gene Variants Linked to Lung Cancer Identified 2Health News:Gene Variants Linked to Lung Cancer Identified 3Health News:Gene Variants Linked to Lung Cancer Identified 4Health News:Digital Technology Exposes Business to Greater Liability 2Health News:Recent Study Finds That a Substantial Number of Public School Districts Conduct Random Drug Testing with High School Students 2
(Date:4/17/2015)... --Research and Markets ( http://www.researchandmarkets.com/research/6tdwh8/medical_device ) ... Device Outsourcing - Global Strategic Business Report" ... analyzes the worldwide markets for Medical Device Outsourcing ... Class I, Class II, and Class III. The ... - Radiology, Orthopedic, Neurology, Cardiology, and Others. ...
(Date:4/17/2015)... Research and Markets ( http://www.researchandmarkets.com/research/lmsnqn/medical_equipment ) ... Rental and Leasing - Global Strategic Business Report" ... the worldwide markets for Medical Equipment Rental and Leasing ... for the US, Japan , ... Annual estimates and forecasts are provided for the ...
(Date:4/17/2015)... , April 17, 2015 ASSESS ... mutation   is a viable alternative to tumour biopsy   ... in all patients with advanced NSCLC   AstraZeneca ... of plasma circulating tumour DNA (ctDNA) testing for epidermal growth ... advanced non-small cell lung cancer (NSCLC) in clinical practice. [ ...
Breaking Medicine Technology:Medical Device Outsourcing (Radiology, Orthopedic, Neurology, Cardiology, and Others) Market 2015 - Global Strategic Business Report 2Medical Device Outsourcing (Radiology, Orthopedic, Neurology, Cardiology, and Others) Market 2015 - Global Strategic Business Report 3Medical Equipment Rental and Leasing Market 2015-2020 - Global Strategic Business Report - Healthcare Spending Slowdown Bodes Well for Medical Equipment Leasing 2"Real World" Data Support Use of Blood Test for EGFR Mutation in Advanced NSCLC 2"Real World" Data Support Use of Blood Test for EGFR Mutation in Advanced NSCLC 3"Real World" Data Support Use of Blood Test for EGFR Mutation in Advanced NSCLC 4
... , WAYNE, Pa., Nov. 20 Escalon Medical Corp. (Nasdaq ... ended September 30, 2009. , For the first ... 2.7%, to $8,435,000 during the three-month period ended September 30, ... The Company reported the decreased net revenue of $8,434,000 ...
... , LOUISVILLE, Ky., Nov. ... today announced a new initiative in the war on methamphetamine. ... electronic tracking program that enforces purchase limitations on over-the-counter (OTC) ... The technology for NPLEx is based on a system ...
Cached Medicine Technology:Escalon(R) Reports First Quarter Fiscal 2010 Results 2Escalon(R) Reports First Quarter Fiscal 2010 Results 3Escalon(R) Reports First Quarter Fiscal 2010 Results 4Escalon(R) Reports First Quarter Fiscal 2010 Results 5Escalon(R) Reports First Quarter Fiscal 2010 Results 6Escalon(R) Reports First Quarter Fiscal 2010 Results 7National System Aims To Minimize Diversion of Cold and Allergy Medicine in Methamphetamine Production 2National System Aims To Minimize Diversion of Cold and Allergy Medicine in Methamphetamine Production 3
This is an antigen-capture assay intended for the detection of histidine-rich protein ll (PfHRP-ll), which is released from Malaria-infected red blood cells....
Core Malaria Pf is a rapid self performing, qualitative, two site sandwich immunoassay for the determination of P. falciparum specific histidine rich protein 2 (Pf HRP-2) in whole blood samples...
Ultraview 1700 Central Monitor...
The Hypervisor VI is a solution for telemetry, LAN and wireless LAN networking. It includes bi-directional communication with Mindray bedside patient monitors and can store waveforms and numeric info...
Medicine Products: