Navigation Links
Obesity Weakens Immune Response
Date:12/12/2007

Study found fat mice had harder time fighting gum disease

WEDNESDAY, Dec. 12 (HealthDay News) -- Obese people find it harder to fight infections, and a weakened immune response may be to blame, suggests a new study from Boston University researchers.

In experiments with mice infected with the bacteria Porphyromonas gingivalis, obese mice had less ability to battle gum infection than their normal-weight counterparts, according to the report in this week's early online edition of the Proceedings of the National Academy of Sciences.

"For years, we have had difficulty understanding why obese people have difficulty clearing an infection," said lead researcher Dr. Salomon Amar, associate dean for research at the university's School of Dental Medicine.

"Now we understand that dysfunction in some of the mechanisms, as a result of the obesity, explain difficulty in clearing the infection and also the difficulty in wound healing," Amar said.

In the study, Amar's team tied silk threads infected with the bacteria around the molars of obese and normal-weight mice. They then compared the animals' responses to infection, by measuring both the amount of bone loss and the growth of the bacteria around their teeth.

The researchers found that the obese mice had a compromised immune response to the bacteria, which made the animals more susceptible to the infection.

Amar's group also looked at the animals' white blood cells, which are the main line of defense against infection. The white cells of obese mice had lower levels of an important signaling molecule, and some of the genes that fight inflammation were altered, the researchers found.

Why obesity has this effect isn't clear, but the researchers think it may involve a signaling pathway that controls a protein called NF-kB. Alterations in this protein may be caused by constant exposure to food, Amar explained. "At some point,
'/>"/>

Copyright©2007 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Virus Could Help Drive Obesity
2. Surgery for severe obesity saves lives
3. Obesity Doesnt Always Equal Diabetes
4. Obesity Rate in U.S. Still Climbing
5. Treating diabetes during pregnancy can break link to childhood obesity
6. ZIP codes and property values predict obesity rates
7. High and mighty: first common height gene identified by researchers behind obesity gene finding
8. Research Links TV/Video Game Playing With Child Obesity; Health Experts Back a New Approach
9. This October, the American Physical Therapy Associations National Physical Therapy Month to Focus on Nations Obesity Epidemic
10. UT Southwesterns obesity research receives $22 million NIH Roadmap grant
11. Genaera Announces Formation of Scientific Advisory Board for Obesity Drug Candidate Trodusquemine (MSI-1436)
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Obesity Weakens Immune Response
(Date:6/3/2015)... Rolling Meadows, IL (PRWEB) June 03, 2015 ... filler manufacturers include additional precautions on product labels ... for their treatments, according to the American Society ... asking manufacturers to include new warnings about the ... fillers into blood vessels. While product labels already ...
(Date:6/3/2015)... Hexagon Geospatial is pleased to announce that ... U.S. Education Challenge, which showcases the top usage of ... in the U.S. , This year’s winner is ... and Civil Engineering at the University of New Mexico. ... and Assessment Based on Hyper-spatial Resolution Natural Color Digital ...
(Date:6/3/2015)... June 03, 2015 EMBARGOED FOR RELEASE UNTIL ... Weight Associated with Proximity of Mother’s Home to Gas Wells ... to a high density of natural gas wells drilled with ... birth weights than women living farther from such wells, according ... Health analysis of southwestern Pennsylvania birth records. , ...
(Date:6/3/2015)... June 03, 2015 Loma Linda University ... negotiations with San Gorgonio Memorial Hospital (SGMH). The SGMH ... Thursday, May 28. , “Loma Linda University Health has ... Kerry Heinrich, chief executive officer, Loma Linda University Medical ... expand our services to this community.” , Under ...
(Date:6/3/2015)... June 03, 2015 Save On Medical ... yesterday, to make shopping for health care procedures easier ... has a fresh look and makes it easier to ... around you. , Now, when patients search for ... and surgical procedures) they can see the provider’s price ...
Breaking Medicine News(10 mins):Health News:ASDSA Supports FDA Fillers Directive 2Health News:ASDSA Supports FDA Fillers Directive 3Health News:ASDSA Supports FDA Fillers Directive 4Health News:Hexagon Geospatial Announces U.S. Education Challenge Winner at HxGN Live 2015 2Health News:Fracking Proximity Associated with Lower Birth Weight 2Health News:Fracking Proximity Associated with Lower Birth Weight 3Health News:Fracking Proximity Associated with Lower Birth Weight 4Health News:Loma Linda University Health and Adventist Health Enter into Exclusive Affiliation Negotiations with San Gorgonio Memorial Hospital 2Health News:Save On Medical Launches New Mobile-Optimized Website 2
... Spread of HIV and Challenge StigmaMENLO PARK, Calif., ... media companies from Latin America announced the establishment ... SIDA (IMLAS) -- the first Latin American Media ... meeting last month held in conjunction with the ...
... of Trade Alerts on stocks making news today. Investors can ... visiting: http://www.BeaconEquity.com/m Today,s Trade Alerts include: Johnson & ... ABT ), Eli Lilly & Co. (NYSE: ... AG (NYSE: NVS ) and GlaxoSmithKline plc (NYSE: ...
... Medical travel company Companion Global Healthcare Inc. ... employer groups now have additional options for saving ... remaining closer to home.Companion Global Healthcare President David ... Hospitals in Hermosillo, Mexico, and Monterrey, Mexico, into ...
... MinnesotaMINNEAPOLIS, Feb. 18 SpectraScience, Inc. (OTC Bulletin ... that it will place its LUMA(R) Cervical Imaging ... Surgery, located in Edina, Minnesota.Dr. James B. Presthus, ... introduction of the LUMA System represents our continued ...
... 18 ,Allscripts announced today that Edge Health Solutions, ... the Allscripts Electronic,Health Record as "EdgeEHR(TM) Powered by ... practice management software on the Mac OS X(R),platform. ... http://www.newscom.com/cgi-bin/prnh/20081013/AQM041LOGO ) , Canada-based ...
... TEMPO™ for Grant Management assists medical affairs departments in deploying ... ... Morrisville, N.C. (PRWEB) February 18, 2009 -- Clinipace, ... has been selected by two pharmaceutical firms to deploy its ...
Cached Medicine News:Health News:Top Latin American Television Companies Commit to Addressing AIDS 2Health News:Top Latin American Television Companies Commit to Addressing AIDS 3Health News:Top Latin American Television Companies Commit to Addressing AIDS 4Health News:Beacon Equity Issues Technical Trade Alerts on Drug Manufacturers: JNJ, ABT, LLY, PFE, NVS, GSK 2Health News:Companion Global Healthcare Expands Service to Include Hospitals in Mexico 2Health News:LUMA Cervical Imaging System Installed in Edina at Minnesota Gynecology 2Health News:LUMA Cervical Imaging System Installed in Edina at Minnesota Gynecology 3Health News:Edge Health Solutions Selects Allscripts Electronic Health Record for Apple Mac OS X Medical Platform 2Health News:Edge Health Solutions Selects Allscripts Electronic Health Record for Apple Mac OS X Medical Platform 3Health News:Edge Health Solutions Selects Allscripts Electronic Health Record for Apple Mac OS X Medical Platform 4Health News:Edge Health Solutions Selects Allscripts Electronic Health Record for Apple Mac OS X Medical Platform 5Health News:Two Pharmaceutical Firms Select Clinipace to Deploy New Grant Management Solution 2
(Date:6/3/2015)... June 3, 2015  Giving people with low vision ... of the International Academy of Low Vision Specialists ... that are at the forefront of low vision care. ... the technology and latest treatment options available to patients ... remedied with traditional means. Recently, doctors in six new ...
(Date:6/3/2015)... RICHMOND, Va. , June 3, 2015  PARI Respiratory ... Kitabis Pak ® .  Kitabis Pak, approved by the FDA ... inhalation solution with a PARI LC PLUS ® Nebulizer ... highlights all the hard work we put into this unique ... package that is easy for patients to use, we also ...
(Date:6/3/2015)... , June 3, 2015  OncoSec Medical ... developing DNA-based intratumoral cancer immunotherapies, today announced that ... healthcare institutional investors to purchase approximately $13.6 million ... has agreed to sell to such investors an ... at a price of $5.50 per share. ...
Breaking Medicine Technology:International Academy of Low Vision Specialists Announces Training of Doctors in Six New States and Canada 2International Academy of Low Vision Specialists Announces Training of Doctors in Six New States and Canada 3International Academy of Low Vision Specialists Announces Training of Doctors in Six New States and Canada 4Kitabis Pak Wins American Package Design Award 2OncoSec Medical Announces $13.6 Million Registered Direct Offering 2OncoSec Medical Announces $13.6 Million Registered Direct Offering 3
... Dec. 18 Just in time for the,holiday season, ... a unique holiday giving initiative launched by Facebook, the ... UNICEF will offer members of the website community,the opportunity ... "Charity Gift." The initiative is an offshoot of Causes, ...
... Lixte,Biotechnology Holdings, Inc. (OTC Bulletin Board: LIXT) ... treatment of cancer, announced the,closing of a private ... its Common Stock at a price of $0.65 ... Capital, Inc. acted as placement agent and,received $65,000 ...
Cached Medicine Technology:UNICEF Partners With Causes on Facebook to Launch 'Charity Gift' Feature 2Lixte Biotechnology Holdings, Inc. Announces Completion of Private Placement 2Lixte Biotechnology Holdings, Inc. Announces Completion of Private Placement 3
... with a high resolution 1640 x ... Non Myd - digital achieves new ... ease of use. Now supplied complete ... install VK-2 image and patient management ...
Nidek offers 3-Dx Digital stereo camera to provide a complete and comprehensive digital imaging platform....
Eye Q PRO is the optimum choice for ophthalmologists and clinicians specializing in advanced pathology and research....
LM-770 Projection Digital Lensmeter...
Medicine Products: