Navigation Links
Obesity Tied to Poor Pancreatic Cancer Surgery Outcomes
Date:3/18/2009

Study finds risk of disease recurrence, death nearly twice that of normal-weight patients

WEDNESDAY, March 18 (HealthDay News) -- Obese pancreatic cancer patients are more likely than non-obese patients to have worse outcomes after surgery to treat their cancer, say U.S. researchers.

"We identified a subset of obese patients (BMI greater than 35) who were at 12-fold increased risk of lymph node metastasis compared with non-obese patients (BMI of 35 or less)," wrote Dr. Jason B. Fleming, of the University of Texas M.D. Anderson Cancer Center in Houston, and colleagues.

The researchers studied data from 285 pancreatic cancer patients who had surgery to remove some or all of the organ.

After about 16 months, 152 patients (53 percent) died. Patients with a body mass index (BMI) higher than 35 survived a median of 13.2 months, compared with 27.4 months for those with a BMI of less than 23. After about 32 months, 15 of 20 patients (75 percent) with a BMI of more than 35 had died, compared with 137 of 265 patients (52 percent) with a BMI of 35 of less.

"The estimated disease-free and overall survival rates were decreased in the obese patients, and the risk of cancer recurrence and death after pancreatectomy (removal of the pancreas) was nearly twice that in non-obese patients," the researchers wrote. "Cancer recurrence was observed in 95 percent (19 of 20) of patients in the group with a BMI of more than 35 vs. 61 percent (161 of 264) of all other patients."

The study is published in the March issue of the journal Archives of Surgery.

Previous studies have noted a link between a BMI higher than 35 and increased risk of death from pancreatic cancer.

"Our findings extend these observations to those patients who undergo surgery to treat pancreatic cancer and suggest that obesity is a host factor affecting tumor biology," Fleming and colleagues concluded.

More information

The American Cancer Society has more about pancreatic cancer.



-- Robert Preidt



SOURCE: JAMA/Archives journals, news release, March 16, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Longer bouts of exercise help prevent childhood obesity
2. Obesity Takes Years Off Your Life
3. Southern California Parents and Kids Take Healthy Steps in Tackling Childhood Obesity
4. UH sociologist has different perspective on obesity epidemic
5. Obesity linked to dangerous sleep apnea in truck drivers
6. Obesity, Diabetes and Heart Disease May Speed Dementia
7. ACSM Partnership Will Combat Childhood Obesity, Get Kids Active
8. HEROES Grants, Education Guide Support Youth Leaders Addressing Childhood Obesity Epidemic
9. Bias Against Obesity Is Found Among Future Dietitians
10. UT School of Public Health Program to Prevent Childhood Obesity Expands to Central Texas Middle Schools
11. Ethnicity May Drive Response to Obesity, Insulin Resistance
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Obesity Tied to Poor Pancreatic Cancer Surgery Outcomes
(Date:4/29/2016)... ... April 30, 2016 , ... World ... the Pick Up Springboard, an automotive invention that improves the storage features of ... worth $162 billion," says Scott Cooper, CEO and Creative Director of World Patent ...
(Date:4/29/2016)... ... 29, 2016 , ... Since launching its annual volunteer campaign ... the footwear industry, has broken all previous participation records in its first two ... states during the months of April and May, the 2016 Footwear Cares initiative ...
(Date:4/29/2016)... ... , ... Our bodies are bombarded daily by environmental and lifestyle factors that ... is to adopt a more healthful diet, but too many people think that food ... Nutritionist and the creator of the Newport Beach Cleanse and 14-Day Eating Plan, disagrees ...
(Date:4/29/2016)... ... 29, 2016 , ... Dr. Bernie Siegel, (M.D.) ... MEDICINE and MIRACLES") addresses touchy topics related to Death live on Dr. ... Dr. Bernie Siegel, author of a plethora of essential books-to-read for physicians and ...
(Date:4/29/2016)... GA (PRWEB) , ... April 29, 2016 , ... Coast ... May 16, 2016, at its new location in the Exchange Furniture Mall at 112 ... raffle for a 50-inch Samsung Smart TV. Plus attendees will have the opportunity to ...
Breaking Medicine News(10 mins):
(Date:4/27/2016)... 2016 Oasmia Pharmaceutical AB ... a new generation of drugs within human and ... for Paclical/Apealea in the Phase III study that ... ovarian cancer. These preliminary results showed non-inferiority between ... carboplatin versus Taxol in combination with carboplatin. In ...
(Date:4/27/2016)... April 27, 2016 At the ... launch of a Phase 2 clinical study of its ... patients undergoing cochlear implantation (CI) surgery. This large, placebo-controlled, ... Germany and France ... ear at the time of surgery. "Despite advances in ...
(Date:4/26/2016)... 26, 2016 US demand for infection ... 4.9 percent annually to $27.6 billion in 2020.  ... to decrease rates of healthcare-associated infections (HAIs) will ... and services.  Although declining, the overall rate of ... levels set by the CDC.  Recent statistics indicate ...
Breaking Medicine Technology: