Navigation Links
Obesity Tied to Poor Pancreatic Cancer Surgery Outcomes

Study finds risk of disease recurrence, death nearly twice that of normal-weight patients

WEDNESDAY, March 18 (HealthDay News) -- Obese pancreatic cancer patients are more likely than non-obese patients to have worse outcomes after surgery to treat their cancer, say U.S. researchers.

"We identified a subset of obese patients (BMI greater than 35) who were at 12-fold increased risk of lymph node metastasis compared with non-obese patients (BMI of 35 or less)," wrote Dr. Jason B. Fleming, of the University of Texas M.D. Anderson Cancer Center in Houston, and colleagues.

The researchers studied data from 285 pancreatic cancer patients who had surgery to remove some or all of the organ.

After about 16 months, 152 patients (53 percent) died. Patients with a body mass index (BMI) higher than 35 survived a median of 13.2 months, compared with 27.4 months for those with a BMI of less than 23. After about 32 months, 15 of 20 patients (75 percent) with a BMI of more than 35 had died, compared with 137 of 265 patients (52 percent) with a BMI of 35 of less.

"The estimated disease-free and overall survival rates were decreased in the obese patients, and the risk of cancer recurrence and death after pancreatectomy (removal of the pancreas) was nearly twice that in non-obese patients," the researchers wrote. "Cancer recurrence was observed in 95 percent (19 of 20) of patients in the group with a BMI of more than 35 vs. 61 percent (161 of 264) of all other patients."

The study is published in the March issue of the journal Archives of Surgery.

Previous studies have noted a link between a BMI higher than 35 and increased risk of death from pancreatic cancer.

"Our findings extend these observations to those patients who undergo surgery to treat pancreatic cancer and suggest that obesity is a host factor affecting tumor biology," Fleming and colleagues concluded.

More information

The American Cancer Society has more about pancreatic cancer.

-- Robert Preidt

SOURCE: JAMA/Archives journals, news release, March 16, 2009

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Longer bouts of exercise help prevent childhood obesity
2. Obesity Takes Years Off Your Life
3. Southern California Parents and Kids Take Healthy Steps in Tackling Childhood Obesity
4. UH sociologist has different perspective on obesity epidemic
5. Obesity linked to dangerous sleep apnea in truck drivers
6. Obesity, Diabetes and Heart Disease May Speed Dementia
7. ACSM Partnership Will Combat Childhood Obesity, Get Kids Active
8. HEROES Grants, Education Guide Support Youth Leaders Addressing Childhood Obesity Epidemic
9. Bias Against Obesity Is Found Among Future Dietitians
10. UT School of Public Health Program to Prevent Childhood Obesity Expands to Central Texas Middle Schools
11. Ethnicity May Drive Response to Obesity, Insulin Resistance
Post Your Comments:
Related Image:
Obesity Tied to Poor Pancreatic Cancer Surgery Outcomes
(Date:10/13/2015)... ... October 13, 2015 , ... ... Anik Singal's newly launched "Publish Academy" training course . Singal's new program, ... for enrollment today, and marketers around the Internet are weighing in with reviews. ...
(Date:10/13/2015)... ... 2015 , ... Scientists in Seattle and Vancouver compared the diagnostic value of ... mesothelioma. Surviving Mesothelioma has just posted an article on the new research. Click ... and the University of British Columbia found that certain genetic alterations were seen just ...
(Date:10/13/2015)... ... October 13, 2015 , ... California Southern ... Nursing. Dr. McLeod—who earned her Doctor of Nursing Practice from the renowned Johns ... spanned four decades. , Dr. McLeod’s long and successful nursing practice included a ...
(Date:10/13/2015)... ... October 13, 2015 , ... ... most people do not breathe correctly. According to T’ai Chi (also spelled “Taiji”) ... learning to breathe correctly, in concert with the 7,000 year old tradition they ...
(Date:10/13/2015)... ... October 13, 2015 , ... In an ongoing ... PediaPlex , a Southlake, Texas, child development and pediatric therapy center, is working ... military families about their options for receiving this kind of care for affected ...
Breaking Medicine News(10 mins):
(Date:10/13/2015)... World Thrombosis Day Interactive Infographic ...   --> World Thrombosis Day Interactive ... promote vital global awareness of thrombosis, its causes, ... the formation of potentially deadly blood clots in ... thromboembolism (VTE) - or the artery (arterial thrombosis) [1] ...
(Date:10/12/2015)... the United States . By early next year, ... the United States . By early next year, ... The University of Texas MD Anderson Cancer Center, Elekta and ... Tesla) MRI-guided linear accelerator in the United States ... a non-clinical capacity. Royal Philips (NYSE: PHG ...
(Date:10/12/2015)... , Oct. 12, 2015 ... the setbacks and the needs of the medical membrane ... of membrane devices within the different medical membrane devices ... blood microfilters/apheresis systems and membrane diagnostic devices. - Gain ... in this market. --> Use this report ...
Breaking Medicine Technology: