Navigation Links
Obesity Might Hinder Treatment of Some Breast Cancers

MONDAY, July 16 (HealthDay News) -- Being obese may affect a woman's response to breast cancer treatment, a small new study suggests.

British researchers looked at 54 postmenopausal women with estrogen receptor-positive breast cancer, meaning that the tumor may grow in the presence of estrogen. More than three-quarters of breast cancers require estrogen to grow, so blocking the production or action of estrogen is one of the main ways to treat the disease.

The researchers found that obese breast cancer patients had higher levels of estrogen than women of normal weight.

The women in the study also were compared according to their body-mass index (BMI). BMI is a measure of obesity based on height and weight, and a BMI of 30 is considered the threshold for obesity. Women with a BMI of 30 to 35 had about three times higher levels of estrogen in their blood than those with a BMI of less than 25, the researchers reported July 16 in the Journal of Clinical Oncology.

After treatment with hormone-suppressing drugs, estrogen levels in the obese women dropped significantly, but still remained at more than double the levels seen in women of normal weight.

The researchers emphasized that women undergoing breast cancer treatment should not be concerned by the findings. They also said the study results may lead to improvements in doctors' ability to select the best treatment for overweight and obese breast cancer patients.

"Our findings are based on laboratory studies, so we would need to carry out clinical trials to tell us whether women with a higher BMI would benefit from changes to their treatment," study senior author Mitch Dowsett, a team leader in the Breakthrough Breast Cancer Research Centre at the Institute of Cancer Research in London, said in an institute news release.

"Women with higher BMIs should certainly not be alarmed by this finding or stop taking their treatment," he said. "[However], our study takes us a step closer to understanding which of the treatment options available might be the most suitable for individual women."

More information

The U.S. National Cancer Institute has more about breast cancer.

-- Robert Preidt

SOURCE: The Institute of Cancer Research, news release, July 16, 2012

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Obesity Alone May Not Hurt Kids Classroom Performance
2. New evidence for link between obesity and circle of friends
3. Vanderbilt study finds obesity linked to kidney injury after heart surgery
4. Obesity, larger waist size associated with better outcomes in heart failure patients
5. Why current strategies for fighting obesity are not working
6. Wayne State University researcher seeks to understand link between obesity, flu severity
7. Researchers find abuse during childhood may contribute to obesity in adulthood
8. Racial make-up of community impacts obesity risk
9. Screen All Adults for Obesity: U.S. Panel
10. STOP Obesity Alliance new state-level members share obstacles, opportunities in addressing obesity
11. Plastics Chemical Linked to Obesity in Kids
Post Your Comments:
Related Image:
Obesity Might Hinder Treatment of Some Breast Cancers
(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... ... fertility once they have been diagnosed with endometriosis. These women need a treatment ... also require a comprehensive approach that can help for preservation of fertility and ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , ... Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. , ... our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First ...
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article published ... unfamiliar with. The article goes on to state that individuals are now more comfortable ... less common operations such as calf and cheek reduction. The Los Angeles area medical ...
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced that ... chosen by their peers for this recognition are considered among the top 2 percent ... special honors as members of this year’s Legal Elite Hall of Fame: Miami ...
(Date:6/24/2016)... ... June 24, 2016 , ... EB Medicine presented its first-ever ... Medicine conference in Ponte Vedra Beach, FL. The awards honor the outstanding work ... Practice and Pediatric Emergency Medicine Practice. , “With this award, we recognize ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016  Consumers have taken ... regulators/payers have placed more emphasis on patient outcomes. ... support programs in the pharmaceutical industry have evolved ... Consequently, pharmaceutical companies are focusing on becoming more ... providing products and services that improve health. ...
(Date:6/24/2016)... 24, 2016  Global Blood Therapeutics, Inc. (GBT) (NASDAQ: ... novel therapeutics for the treatment of grievous blood-based ... closing of its previously announced underwritten public offering ... public offering price of $18.75 per share. All ... by GBT. GBT estimates net proceeds from the ...
(Date:6/24/2016)... Dublin - ... " Global Markets for Spectroscopy Equipment" report ... This report focuses on the global market of ... applications in various applications. The report deals with spectroscopy ... industries: pharmaceutical and biotechnology, food and beverage, and environmental ...
Breaking Medicine Technology: