Navigation Links
Obesity Might Hinder Treatment of Some Breast Cancers

MONDAY, July 16 (HealthDay News) -- Being obese may affect a woman's response to breast cancer treatment, a small new study suggests.

British researchers looked at 54 postmenopausal women with estrogen receptor-positive breast cancer, meaning that the tumor may grow in the presence of estrogen. More than three-quarters of breast cancers require estrogen to grow, so blocking the production or action of estrogen is one of the main ways to treat the disease.

The researchers found that obese breast cancer patients had higher levels of estrogen than women of normal weight.

The women in the study also were compared according to their body-mass index (BMI). BMI is a measure of obesity based on height and weight, and a BMI of 30 is considered the threshold for obesity. Women with a BMI of 30 to 35 had about three times higher levels of estrogen in their blood than those with a BMI of less than 25, the researchers reported July 16 in the Journal of Clinical Oncology.

After treatment with hormone-suppressing drugs, estrogen levels in the obese women dropped significantly, but still remained at more than double the levels seen in women of normal weight.

The researchers emphasized that women undergoing breast cancer treatment should not be concerned by the findings. They also said the study results may lead to improvements in doctors' ability to select the best treatment for overweight and obese breast cancer patients.

"Our findings are based on laboratory studies, so we would need to carry out clinical trials to tell us whether women with a higher BMI would benefit from changes to their treatment," study senior author Mitch Dowsett, a team leader in the Breakthrough Breast Cancer Research Centre at the Institute of Cancer Research in London, said in an institute news release.

"Women with higher BMIs should certainly not be alarmed by this finding or stop taking their treatment," he said. "[However], our study takes us a step closer to understanding which of the treatment options available might be the most suitable for individual women."

More information

The U.S. National Cancer Institute has more about breast cancer.

-- Robert Preidt

SOURCE: The Institute of Cancer Research, news release, July 16, 2012

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Obesity Alone May Not Hurt Kids Classroom Performance
2. New evidence for link between obesity and circle of friends
3. Vanderbilt study finds obesity linked to kidney injury after heart surgery
4. Obesity, larger waist size associated with better outcomes in heart failure patients
5. Why current strategies for fighting obesity are not working
6. Wayne State University researcher seeks to understand link between obesity, flu severity
7. Researchers find abuse during childhood may contribute to obesity in adulthood
8. Racial make-up of community impacts obesity risk
9. Screen All Adults for Obesity: U.S. Panel
10. STOP Obesity Alliance new state-level members share obstacles, opportunities in addressing obesity
11. Plastics Chemical Linked to Obesity in Kids
Post Your Comments:
Related Image:
Obesity Might Hinder Treatment of Some Breast Cancers
(Date:11/25/2015)... ... November 25, 2015 , ... Since its ... comprehensive solutions involving adult stem cell therapies to patients with chronic degenerative medical ... name as a Registered Trademark (RTM). , Organizations are required to hold a ...
(Date:11/24/2015)... ... November 24, 2015 , ... Dr. Todd S. Afferica, a noted ... to many of his patients. Dr. Afferica now uses the BIOLASE WaterLase iPlus 2.0™ ... of time the doctor uses other traditional cutting tools, such as the scalpel and ...
(Date:11/24/2015)... ... , ... In an article published November 12th by Obesity News ... or are not eligible for bariatric surgery. The article explains that candidates for weight ... 100 pounds overweight, or have a BMI of 35 and over with at least ...
(Date:11/24/2015)... Salt Lake City, UT (PRWEB) , ... November 24, 2015 , ... ... according to Forbes Magazine. For a business, it is critical that the first impression ... of a business, they are not likely to buy anything or want to return. ...
(Date:11/24/2015)... ... 2015 , ... Cancer patients, survivors, caregivers, family members and ... taping of the next CURE Connections® video series on Saturday, Dec. ... at Georgetown University Hotel & Conference Center in Washington, D.C. , CURE Connections, ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... , November 24, 2015 ... --> adds Latest Guidebook for ... of 217 pages published in November 2015 to ... online business intelligence library at . ... of the fastest growing global economies with a ...
(Date:11/24/2015)... LONDON , November 24, 2015 ... platform for scientists - since it was launched just six ... collaboration, reference management and authoring platform for scientists - since ... One million references have been loaded on to F1000Workspace ... for scientists - since it was launched just six months ...
(Date:11/24/2015)... , November 24, 2015 st  Scientific ... North America (RSNA) taking place in Chicago ... Booth 1122, Hall A. --> st  Scientific Assembly and ... (RSNA) taking place in Chicago ... Hall A. --> Molecular Dynamics will present its revolutionary ...
Breaking Medicine Technology: