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Obesity During Pregnancy Linked to Raised Asthma Risk in Kids
Date:7/22/2014

hat certain factors in the genetic make-up of the mother predisposes both to obesity (in herself) and to asthma (in her child). Most likely there is a combination of all these playing a role," Forno suggested.

Forno noted that it is important that all women of reproductive age maintain a healthy weight, especially if they are trying to get pregnant.

"It is also important to have adequate weight management and healthy nutrition during pregnancy, because excessive weight gain [during pregnancy] also increases the risk of childhood asthma. This is of course in addition to all the other benefits of a healthy weight and diet," he said.

The report appears in the August print edition of the journal Pediatrics.

Previous studies have found that obesity leads to an increased risk of asthma. And, among children with asthma, obesity leads to increased severity of the disease. There has also been increasing interest in the early origins of childhood asthma, Forno said.

To see how a mother's weight might be linked to the development of asthma in her children, Forno and his colleagues reviewed 14 previously published studies that included over 100,000 mother-child pairs.

The risk of a child having asthma was 36 percent higher for mothers who were obese during pregnancy compared to normal-weight expectant mothers. The study authors suggest that, for women who do not have a history of asthma, the effect of obesity during pregnancy may be an even stronger influence on whether or not a child develops asthma.

Although there appeared to be a slight association between an overweight mom-to-be and asthma in her offspring, the association wasn't statistically significant, according to the study.

Dr. David Mendez, a neonatologist at Miami Children's Hospital, said that this study asks a question that only additional research can answer. Such research would need to take into account the mother's history of asthma and the baby's exposur
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