Navigation Links
Obesity Boosts Esophageal Cancer Risk
Date:10/11/2007

Very overweight people face 6 times the odds, study finds

THURSDAY, Oct. 11 (HealthDay News) -- Obese people are six times more likely to develop esophageal cancer than people with healthy weight, says an Australian study that looked at 800 people with esophageal tumors and 1,600 people without the disease.

People with a body mass index (BMI) of 40 or more were six times as likely to have esophageal cancer as those with a BMI between 18.5 and 25 (a BMI of 30 is considered the threshold for obesity).

According to a team from the Queensland Institute of Medical Research in Brisbane, the finding held true even after accounting for other factors known to be linked to the disease, such as high alcohol consumption and smoking.

This suggests that obesity is an independent risk factor for esophageal cancer, said the study authors, who explained that higher levels of fat tissue in the body increase insulin production. This, in turn, boosts levels of circulating insulin-like growth factor.

Both these hormones stimulate cell growth and inhibit cell death -- conditions that can lead to cancer development, the team said.

The researchers also noted that fat cells produce hormones called adipocytokines that speed up cell growth and play a role in inflammatory processes.

Repeated symptoms of severe heartburn or gastrointestinal reflux disease were also associated with a much higher risk of esophageal cancer, the researchers said. The more frequent the symptoms, the greater the risk. Gastrointestinal reflux disease quintupled the risk of esophageal cancer, while a combination of acid reflux and obesity increased the risk by a factor of 16.

The study was published Oct. 11 in the online edition of the journal Gut.

More information

The American Cancer Society has more about esophageal cancer.



-- Robert Preidt



SOURCE: BMJ Specialist Journals, new release, Oct. 11, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Lean Protein Could Be Key to Obesity Drugs
2. Breast Feeding prevents obesity later on in life
3. Obesity raises IVF miscarriage risk
4. Obesity a risk for pancreatic cancer
5. Diabetes, obesity rates shooting up
6. Midlife obesity linked to risk of dementia
7. Scientists crack mechanism of Leptin-Obesity Hormone
8. Rise In Obesity Among North Qeenslanders
9. Starving leads to obesity
10. Obesity shortens lifespan
11. Antidepressant helps obesity
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/12/2016)... ... February 12, 2016 , ... Fisher House Foundation Chairman ... John J. Lee, Nevada Military Support Alliance president Scott Bensing, and Peggy Kearns Director, ... VA Southern Nevada Healthcare System. This will be the first Fisher House in ...
(Date:2/12/2016)... (PRWEB) , ... February 12, 2016 , ... ... of the Pittsburgh metro area, celebrates the beginning of the latest charity campaign ... develop social skills through art. Donations to this worthy cause are currently being ...
(Date:2/12/2016)... ... February 12, 2016 , ... Mediaplanet today announces the ... print component of “Revolutionizing Cancer Care” is distributed within the February 12 issue ... with a circulation of approximately 250,000 copies and an estimated readership of 750,000 ...
(Date:2/12/2016)... ... 2016 , ... A lot has been reported about the fitness routines of ... health and wellness resources most Americans could ever dream of having at their disposal. ... as frenetic as the U.S. President. , In honor of President’s Day on ...
(Date:2/12/2016)... ... February 12, 2016 , ... Basketball is a game for ... of the Peety PoppersTM series, sign language translation is featured in the top right ... wellness in Peety PoppersTM lessons has a sign language translator to teach kids the ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... Ambulances announces its first delivery in the state of ... Emergency Medical Services (EMS) consisting of four vehicles: three ... Emergency Vehicles in Lecanto, FL , USA, ... the latest in Demers, ongoing expansion of sales.  ... --> Benoit LaFortune , Executive Vice President at Demers. ...
(Date:2/12/2016)... SAN JOSE, Calif. , Feb. 12, 2016  SI-BONE, Inc., ... Implant System ® ("iFuse"), a minimally invasive surgical (MIS) device ... announced that National Government Services, Inc. (NGS), the Medicare Administrative Contractor ... Illinois , Maine , ... Hampshire , New York , ...
(Date:2/12/2016)... 2016  Sequent Medical, Inc. announced today that it ... the safety and effectiveness of the WEB™ Aneurysm Embolization ... aneurysms.  Prof Laurent Spelle , MD, Head of ... France and Principal Investigator of the CLARYS ... and Germany.  Although patients with ruptured aneurysms ...
Breaking Medicine Technology: