Navigation Links
Obesity Boosts Esophageal Cancer Risk
Date:10/11/2007

Very overweight people face 6 times the odds, study finds

THURSDAY, Oct. 11 (HealthDay News) -- Obese people are six times more likely to develop esophageal cancer than people with healthy weight, says an Australian study that looked at 800 people with esophageal tumors and 1,600 people without the disease.

People with a body mass index (BMI) of 40 or more were six times as likely to have esophageal cancer as those with a BMI between 18.5 and 25 (a BMI of 30 is considered the threshold for obesity).

According to a team from the Queensland Institute of Medical Research in Brisbane, the finding held true even after accounting for other factors known to be linked to the disease, such as high alcohol consumption and smoking.

This suggests that obesity is an independent risk factor for esophageal cancer, said the study authors, who explained that higher levels of fat tissue in the body increase insulin production. This, in turn, boosts levels of circulating insulin-like growth factor.

Both these hormones stimulate cell growth and inhibit cell death -- conditions that can lead to cancer development, the team said.

The researchers also noted that fat cells produce hormones called adipocytokines that speed up cell growth and play a role in inflammatory processes.

Repeated symptoms of severe heartburn or gastrointestinal reflux disease were also associated with a much higher risk of esophageal cancer, the researchers said. The more frequent the symptoms, the greater the risk. Gastrointestinal reflux disease quintupled the risk of esophageal cancer, while a combination of acid reflux and obesity increased the risk by a factor of 16.

The study was published Oct. 11 in the online edition of the journal Gut.

More information

The American Cancer Society has more about esophageal cancer.



-- Robert Preidt



SOURCE: BMJ Specialist Journals, new release, Oct. 11, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Lean Protein Could Be Key to Obesity Drugs
2. Breast Feeding prevents obesity later on in life
3. Obesity raises IVF miscarriage risk
4. Obesity a risk for pancreatic cancer
5. Diabetes, obesity rates shooting up
6. Midlife obesity linked to risk of dementia
7. Scientists crack mechanism of Leptin-Obesity Hormone
8. Rise In Obesity Among North Qeenslanders
9. Starving leads to obesity
10. Obesity shortens lifespan
11. Antidepressant helps obesity
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2016)... Killeen, Texas (PRWEB) , ... May 27, 2016 , ... ... with satisfying Army body fat composition regulations. This is the first time that ... are normally screened at least every six months to ensure they meet the prescribed ...
(Date:5/27/2016)... , ... May 27, 2016 , ... ... scholarships to students studying complementary medicine. Allison Outerbridge is this year’s Life ... award on May 18 at the university’s Student Leadership Awards ceremony. , Outerbridge ...
(Date:5/26/2016)... ... May 26, 2016 , ... There are many ways to cook ... Council (NHDSC) suggests that Americans prefer their dogs straight off the grill. Of the ... is their favorite way to cook a hot dog, far outpacing other cooking methods ...
(Date:5/26/2016)... Missouri (PRWEB) , ... May 26, 2016 , ... ... quality and clinical outcomes, hosted members and suppliers for its inaugural Member Conference ... focus on their mission of elevating the operational health of America’s healthcare providers. ...
(Date:5/26/2016)... Washington, D.C. (PRWEB) , ... May 26, 2016 , ... ... the men and women who lost their lives in military battle for the country. ... discount cards in 2015 to provide more programs that empower independence for disabled military ...
Breaking Medicine News(10 mins):
(Date:5/27/2016)... 27, 2016 Amarantus BioScience Holdings, Inc. ... products for Regenerative Medicine, Neurology and Orphan Diseases, today announced that ... at two upcoming investor conferences: SeeThru Equity MicroCap ... New York City , NY When: ... Marcum MicroCap Conference   Where: Grand Hyatt Hotel, 109 ...
(Date:5/26/2016)... TARE (Transarterial Radio-embolization) Using ... and Overall Decreased Use of Hospital Resource ... specialist healthcare company, has today announced the publication ... of ISPOR (International Society for Pharmacoeconomics and Outcomes ... using yttrium-90 glass microspheres is associated with cost ...
(Date:5/25/2016)... -- According to a new market research ... by Therapeutic Area (Oncology, Cosmeceutical/Plastic Surgery), by Application (Drug ... Hospitals/ Clinics) - Forecast to 2021", published by MarketsandMarkets, ... the forecast period of 2016 to 2021. This market ... from USD 117.3 Million in 2016, at a CAGR ...
Breaking Medicine Technology: