Navigation Links
Obesity Boosts Esophageal Cancer Risk
Date:10/11/2007

Very overweight people face 6 times the odds, study finds

THURSDAY, Oct. 11 (HealthDay News) -- Obese people are six times more likely to develop esophageal cancer than people with healthy weight, says an Australian study that looked at 800 people with esophageal tumors and 1,600 people without the disease.

People with a body mass index (BMI) of 40 or more were six times as likely to have esophageal cancer as those with a BMI between 18.5 and 25 (a BMI of 30 is considered the threshold for obesity).

According to a team from the Queensland Institute of Medical Research in Brisbane, the finding held true even after accounting for other factors known to be linked to the disease, such as high alcohol consumption and smoking.

This suggests that obesity is an independent risk factor for esophageal cancer, said the study authors, who explained that higher levels of fat tissue in the body increase insulin production. This, in turn, boosts levels of circulating insulin-like growth factor.

Both these hormones stimulate cell growth and inhibit cell death -- conditions that can lead to cancer development, the team said.

The researchers also noted that fat cells produce hormones called adipocytokines that speed up cell growth and play a role in inflammatory processes.

Repeated symptoms of severe heartburn or gastrointestinal reflux disease were also associated with a much higher risk of esophageal cancer, the researchers said. The more frequent the symptoms, the greater the risk. Gastrointestinal reflux disease quintupled the risk of esophageal cancer, while a combination of acid reflux and obesity increased the risk by a factor of 16.

The study was published Oct. 11 in the online edition of the journal Gut.

More information

The American Cancer Society has more about esophageal cancer.



-- Robert Preidt



SOURCE: BMJ Specialist Journals, new release, Oct. 11, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Lean Protein Could Be Key to Obesity Drugs
2. Breast Feeding prevents obesity later on in life
3. Obesity raises IVF miscarriage risk
4. Obesity a risk for pancreatic cancer
5. Diabetes, obesity rates shooting up
6. Midlife obesity linked to risk of dementia
7. Scientists crack mechanism of Leptin-Obesity Hormone
8. Rise In Obesity Among North Qeenslanders
9. Starving leads to obesity
10. Obesity shortens lifespan
11. Antidepressant helps obesity
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/22/2017)... ... September 22, 2017 , ... ... setbacks, a senior finds a new lease on life with assistance from CreditAssociates. ... people resolve their problem with unsecured debt. The senior is one of the ...
(Date:9/22/2017)... , ... September 22, 2017 , ... ... on the fallacy of an obligatory tithe, and the freedom experienced when breaking ... the creation of published author, Lysa M. Harrison. , Published by Christian Faith ...
(Date:9/22/2017)... ... ... “Fruit of the Spirit: “Love””: a delightful adventure of two friends who ... the Spirit: “Love”” is the creation of published author, Halimah Jones, who was born ... is an avid writer, her inspiration for “Fruit of the Spirit: “Love”” blossomed from ...
(Date:9/21/2017)... Aliso Viejo, CA (PRWEB) , ... September 21, 2017 , ... ... never been so fun and easy to do. Users can select from up to ... more all with a click of a mouse all within Final Cut Pro ...
(Date:9/21/2017)... ... September 21, 2017 , ... Promotional Communication:, Keeping Up ... , In the competitive world of drug and device marketing and promotion, drug ... FDA rules. , The FDA has issued two draft guidances that are the ...
Breaking Medicine News(10 mins):
(Date:9/19/2017)... , Sept. 19, 2017   ZirMed Inc ., ... analytics, today announced that it has been ranked #1 by ... Black Book™ Rankings 2017 User Survey. ZirMed was recognized ... for large hospitals and medical centers over 200 beds and ... Book,s healthcare technology user survey history. ...
(Date:9/12/2017)... NEW YORK , Sept. 12, 2017   EcoVadis , the ... chains, has published the first annual edition of its Global CSR Risk ... 20,400 companies evaluated by EcoVadis, based on Scorecard Ratings that analyzed nearly ... ... Performance Index ...
(Date:9/9/2017)... -- Dealmed Medical Supplies, New York City,s ... drugs, vaccines, and specialty medical products and services, announced ... acquire Vantage Medical Supplies, a major distributor of medical ... York . ... practices, will operate under the Dealmed name as of ...
Breaking Medicine Technology: