Navigation Links
Obesity Boosts Esophageal Cancer Risk
Date:10/11/2007

Very overweight people face 6 times the odds, study finds

THURSDAY, Oct. 11 (HealthDay News) -- Obese people are six times more likely to develop esophageal cancer than people with healthy weight, says an Australian study that looked at 800 people with esophageal tumors and 1,600 people without the disease.

People with a body mass index (BMI) of 40 or more were six times as likely to have esophageal cancer as those with a BMI between 18.5 and 25 (a BMI of 30 is considered the threshold for obesity).

According to a team from the Queensland Institute of Medical Research in Brisbane, the finding held true even after accounting for other factors known to be linked to the disease, such as high alcohol consumption and smoking.

This suggests that obesity is an independent risk factor for esophageal cancer, said the study authors, who explained that higher levels of fat tissue in the body increase insulin production. This, in turn, boosts levels of circulating insulin-like growth factor.

Both these hormones stimulate cell growth and inhibit cell death -- conditions that can lead to cancer development, the team said.

The researchers also noted that fat cells produce hormones called adipocytokines that speed up cell growth and play a role in inflammatory processes.

Repeated symptoms of severe heartburn or gastrointestinal reflux disease were also associated with a much higher risk of esophageal cancer, the researchers said. The more frequent the symptoms, the greater the risk. Gastrointestinal reflux disease quintupled the risk of esophageal cancer, while a combination of acid reflux and obesity increased the risk by a factor of 16.

The study was published Oct. 11 in the online edition of the journal Gut.

More information

The American Cancer Society has more about esophageal cancer.



-- Robert Preidt



SOURCE: BMJ Specialist Journals, new release, Oct. 11, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Lean Protein Could Be Key to Obesity Drugs
2. Breast Feeding prevents obesity later on in life
3. Obesity raises IVF miscarriage risk
4. Obesity a risk for pancreatic cancer
5. Diabetes, obesity rates shooting up
6. Midlife obesity linked to risk of dementia
7. Scientists crack mechanism of Leptin-Obesity Hormone
8. Rise In Obesity Among North Qeenslanders
9. Starving leads to obesity
10. Obesity shortens lifespan
11. Antidepressant helps obesity
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/7/2016)... , ... December 07, 2016 , ... “The Road To ... an everyday trial, not a one hour a week showing of hands. “The Road ... , Tom begins, “Perhaps you are familiar with the brass ring that you could ...
(Date:12/7/2016)... ... 07, 2016 , ... “Fred Rides a Train” allows readers to tag along ... “Fred Rides a Train” is the creation of published author, Janet Morrison, who has ... in Michigan. The "Fred, the Dog" series is her first attempt at writing for ...
(Date:12/7/2016)... (PRWEB) , ... December 07, 2016 , ... ... was honored to present at the International Probiotic Association’s Washington DC workshop on ... government regulators to engage in dialog regarding probiotic dietary supplement regulations. , ...
(Date:12/6/2016)... ... December 06, 2016 , ... People with Parkinson’s ... seen on a type of MRI, according to a study appearing online in ... central nervous system characterized by tremors or trembling and stiffness in the limbs, ...
(Date:12/6/2016)... (PRWEB) , ... December 06, 2016 , ... Individuals who ... measures, such as drinking more water or limiting their exposure to the sun, according ... health and beauty group Beverly Hills Physicians (BHP) notes that, while preventive measures to ...
Breaking Medicine News(10 mins):
(Date:12/6/2016)... , Dec. 6, 2016 Radioisotopes are radioactive ... are produced either by using nuclear research reactor or ... form of alpha, beta or gamma when changed to ... used in Nuclear medicine, specifically in medical diagnostics. In ... information about a human body,s functioning. Radiotherapy is also ...
(Date:12/6/2016)... Human Vaccines Market: Scope and Methodology ... country wise analysis of the human vaccines market. ... vaccines products, raw material suppliers, vaccine processing companies, ... The report provides qualitative and quantitative analysis ... comprises market dynamics, trends, product overview, and country-level ...
(Date:12/6/2016)... 2016 Two new disaster drones delivered telemedical ... mass casualty event Tuesday at John Bell Airport in ... before an audience including Mississippi ... Security, Federal Law Enforcement Agencies, and the United Nations. ... (Health Integrated Rescue Operations), was developed by Italo ...
Breaking Medicine Technology: