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Obesity, physical inactivity linked with risk for certain molecular subtype of colorectal cancer
Date:2/26/2013

re able to identify individuals who are prone to develop CTNNB1-negative cancer, then it would be possible to strongly recommend physical activity."

In addition, the data indicated that CTNNB1 could be a potential target for chemoprevention and treatment, according to Ogino. He called for more population-based, large-scale databases to facilitate molecular pathological epidemiology research.

"Currently, most population-based studies do not take tumor heterogeneity into consideration, and typically colon cancer is treated as a single disease," Ogino said. "We need to integrate molecular pathology and epidemiology in education and research to facilitate integrative science and improve public health."


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Contact: Jeremy Moore
jeremy.moore@aacr.org
215-446-7109
American Association for Cancer Research
Source:Eurekalert

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