Navigation Links
Obesity, excess weight gain during pregnancy linked to heavier babies in African-American women
Date:2/11/2013

(Boston) Epidemiologists at Boston University School of Public Health (BUSPH) have found that pre-pregnancy obesity and excess weight gain during pregnancy in African-American women are associated with an increased risk of giving birth to an abnormally large baby. Macrosomia, which is defined as a newborn weighing more than 4,000 grams at birth (approximately 8.8 pounds), can cause delivery complications such as hemorrhage, infection, the need for a caesarean section, preeclampsia and perinatal mortality. The study, which appears online in the journal Obesity, was conducted by researchers at the Slone Epidemiology Center using data from 59,000 African-American women participating in the Black Women's Health Study.

The investigators compared mothers of 691 full term infants weighing more than 4,000 grams with mothers of 5,996 full-term infants weighing less than 4,000 grams. Overall obesity, measured by body mass index (BMI) of greater than 30, was associated with a two-fold increased risk of macrosomia. After accounting for differences in BMI, the risk of macrosomia also was significantly higher among women with a pre-pregnancy waist circumference greater than 35 inches compared with less than 27 inches.

Maternal obesity may increase the risk of macrosomia due to greater energy accumulation by the fetus from increased maternal glucose concentrations and insulin resistance. Central adiposity, or weight gain around the waist, also is related to glucose and insulin metabolic changes, independent of overall obesity. Few studies have examined the association between central adiposity and infant birth weight.

Gestational weight gain above the range recommended by the 2009 Institute of Medicine (IOM) guidelines also was associated with an increased risk of macrosomia and the association was present within each category of pre-pregnancy BMI: 25-35 pounds for BMI 18.5-24.9 kg/m2 (normal weight); 15-25 pounds for BMI 25-29.9 kg/m2 (overweight); and 11-20 pounds for BMI ≥30 kg/m2 (obese). These data indicate that overall and central obesity predict the risk of macrosomia, and that pregnancy weight gain is a strong determinant of risk.

"In addition to maintaining a healthy weight and waistline before pregnancy, our data suggest that it is especially important for obese women to adhere to the IOM guidelines for pregnancy weight gain to reduce their risk of macrosomia," said senior author Lauren A. Wise, ScD, an associate professor of epidemiology at BUSPH.


'/>"/>

Contact: Jenny Eriksen Leary
jenny.eriksen@bmc.org
617-638-6841
Boston University Medical Center
Source:Eurekalert

Related medicine news :

1. Researchers identify role for protein linked to obesity, type 2 diabetes
2. Use Social Media to Fight Childhood Obesity, Heart Experts Say
3. Study Supports Link Between Obesity, Cavities in Homeless Kids
4. In obesity, a micro-RNA causes metabolic problems
5. What babies eat after birth likely determines lifetime risk of obesity, rat study suggests
6. Obesity, larger waist size associated with better outcomes in heart failure patients
7. Wayne State University researcher seeks to understand link between obesity, flu severity
8. Obesity, A Contributing Cause Of Arthritis Of The Knee, Is Now Being Treated With Regenerative Medicine At The Center For Regenerative Medicine
9. Peaches, plums, nectarines give obesity, diabetes slim chance
10. Obesity, Depression Blamed for Daytime Sleepiness Epidemic
11. Obesity, depression found to be root causes of daytime sleepiness
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/11/2016)... ... February 11, 2016 , ... Husted Kicking has ... Diego, CA, on February 6th & 7th, 2016 according to kicking coach Michael Husted. ... not invited to the NFL’s combine in Indianapolis,” says Husted. “The NFL uses a ...
(Date:2/11/2016)... AZ (PRWEB) , ... February 11, 2016 , ... As ... with support of the Million Dollar Round Table Foundation (MDRTF), has gifted $10,000 to ... according to Colleen’s Dream Foundation President Billy Cundiff. , “We are honored to support ...
(Date:2/10/2016)... ... February 10, 2016 , ... Early this week, Team Iconic at J. ... Nestlé KITKAT as the first global confectionery brand sourced from 100% sustainable cocoa. , ... quality of their product, through activities that focus on better farming, better lives and ...
(Date:2/10/2016)... Fort Walton Beach, Florida (PRWEB) , ... February ... ... that the innovative weather-forecasting company is unveiling its revolutionary new 2.0 version at ... new platform, MetLoop has “put the power of the world's most advanced weather ...
(Date:2/10/2016)... ... February 10, 2016 , ... ... Guard, to associations of medical professionals throughout the country. The Guard was specifically ... assessments, policies and procedures, employee training, regulatory updates, and compliance coaching. , In ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... England och PITTSBURGH ... Erbjudandet lämnas inte, och detta pressmeddelande ... indirekt, i eller till, och inga anmälningssedlar ... av aktieägare i, något land där Erbjudandet, ... accept av Erbjudandet skulle strida mot tillämpliga ...
(Date:2/10/2016)... A new report from business intelligence provider GBI Research ... Alzheimer,s disease market will more than double from just under $5 billion in ... Rate (CAGR) of 11%. Canada , France ... Spain , the UK, and Japan , and ... --> Canada , France , ...
(Date:2/10/2016)... , Feb. 10, 2016 Urologix, the market ... treatment of Benign Prostatic Hyperplasia (BPH), announces new private ... Keswani , a medical device industry veteran of more ... Limited Liability Company.  Plymouth, Minn. ... lines, Cooled ThermoTherapy™ and Prostiva® RF Therapy, will continue ...
Breaking Medicine Technology: