Navigation Links
Obesity, Exercise May Affect Risk for Key Type of Colon Cancer
Date:2/26/2013

TUESDAY, Feb. 26 (HealthDay News) -- Obesity increases a person's risk for a certain type of colorectal cancer, while exercise lowers the risk, according to a new study.

Researchers analyzed data from women in the U.S. Nurses' Health Study and men in the Health Professionals Study to determine if there was a link between weight, exercise and the risk for CTNNB1-positive or CTNNB1-negative colorectal cancer.

CTNNB1 is a molecule implicated in cancer and obesity.

A higher body-mass index, or BMI (a measurement of body fat based on height and weight), was associated with an increased risk of CTNNB1-negative colorectal cancer, while physical activity was associated with a lower risk.

BMI and physical activity had no effect on the risk for CTNNB1-positive colorectal cancer, according to the study appearing Feb. 26 in the journal Cancer Research.

"Our results provide additional evidence for a causal role of obesity and a physically inactive lifestyle in a specific molecular subtype of colorectal cancer," Dr. Shuji Ogino, an associate professor of pathology at Dana-Farber Cancer Institute and an associate professor in the department of epidemiology at Harvard School of Public Health, said in a journal news release.

"If physicians are able to identify individuals who are prone to develop CTNNB1-negative cancer, then it would be possible to strongly recommend physical activity," Ogino added.

The findings also suggest that CTNNB1 could be a potential target for drugs to prevent and treat colorectal cancer in certain patients, Ogino said.

More information

The American Cancer Society has more about colorectal cancer.

-- Robert Preidt

SOURCE: Cancer Research, news release, Feb. 26, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Obesity, physical inactivity linked with risk for certain molecular subtype of colorectal cancer
2. Outdoor Fast-Food Ads Linked to Obesity, Study Suggests
3. Obesity, excess weight gain during pregnancy linked to heavier babies in African-American women
4. Researchers identify role for protein linked to obesity, type 2 diabetes
5. Use Social Media to Fight Childhood Obesity, Heart Experts Say
6. Study Supports Link Between Obesity, Cavities in Homeless Kids
7. In obesity, a micro-RNA causes metabolic problems
8. What babies eat after birth likely determines lifetime risk of obesity, rat study suggests
9. Obesity, larger waist size associated with better outcomes in heart failure patients
10. Wayne State University researcher seeks to understand link between obesity, flu severity
11. Obesity, A Contributing Cause Of Arthritis Of The Knee, Is Now Being Treated With Regenerative Medicine At The Center For Regenerative Medicine
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Obesity, Exercise May Affect Risk for Key Type of Colon Cancer
(Date:4/30/2016)... Michigan (PRWEB) , ... May 01, 2016 , ... Serenity ... approach to rehabilitation, has produced a new video that focuses on one of the ... their recent sessions and clips from interviews with a participating patients and the Yoga ...
(Date:4/30/2016)... ... April 30, 2016 , ... ... President and CEO of EMED, today signed a multifaceted agreement which will allow ... the Northern Caribbean University Department of Natural and Applied Sciences, Allied Health and ...
(Date:4/29/2016)... ... April 30, 2016 , ... Mercy College is expanding ... The following programs will be expanding due to high demand: Master of Business Administration ... will begin this summer. , School of Business Graduate Program Chair Dr. ...
(Date:4/29/2016)... ... April 29, 2016 , ... Our bodies are bombarded ... to confront and deal with these stressors is to adopt a more healthful diet, ... for you. Risa Groux, a certified Holistic Nutritionist and the creator of the Newport ...
(Date:4/29/2016)... ... April 29, 2016 , ... Conditions were ideal for Global ... Park on Sunday, with sunny skies, a light breeze and temperatures in the 60s. ... , The 5k Run and Walk and 1-mile walk were held to increase ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... NEW YORK , April 28, 2016 ... of online consumer insights on healthcare, announced today that ... in their report Cool Vendor in Life Sciences, ... , April 15, 2016.  The report focuses on life-science- ... to gain insight from patients and doctors, confirm medication ...
(Date:4/28/2016)... April 28, 2016   Acsis , a leading ... leading IT market research and advisory firm IDC has ... IDC MarketScape: Worldwide Pharmaceutical Track and Trace Software 2016 ... provides an assessment of the capabilities and business strategies ... software market. Logo - http://photos.prnewswire.com/prnh/20160427/360791LOGO ...
(Date:4/27/2016)...  Hologic, Inc. (Nasdaq: HOLX ) ... fiscal second quarter ended March 26, 2016.  GAAP ... 41.2%, and non-GAAP diluted EPS of $0.47 increased ... a reported basis, and 6.3% on a constant ... good quarter, highlighted by 14.6% growth in non-GAAP ...
Breaking Medicine Technology: