Navigation Links
Obesity, Exercise May Affect Risk for Key Type of Colon Cancer
Date:2/26/2013

TUESDAY, Feb. 26 (HealthDay News) -- Obesity increases a person's risk for a certain type of colorectal cancer, while exercise lowers the risk, according to a new study.

Researchers analyzed data from women in the U.S. Nurses' Health Study and men in the Health Professionals Study to determine if there was a link between weight, exercise and the risk for CTNNB1-positive or CTNNB1-negative colorectal cancer.

CTNNB1 is a molecule implicated in cancer and obesity.

A higher body-mass index, or BMI (a measurement of body fat based on height and weight), was associated with an increased risk of CTNNB1-negative colorectal cancer, while physical activity was associated with a lower risk.

BMI and physical activity had no effect on the risk for CTNNB1-positive colorectal cancer, according to the study appearing Feb. 26 in the journal Cancer Research.

"Our results provide additional evidence for a causal role of obesity and a physically inactive lifestyle in a specific molecular subtype of colorectal cancer," Dr. Shuji Ogino, an associate professor of pathology at Dana-Farber Cancer Institute and an associate professor in the department of epidemiology at Harvard School of Public Health, said in a journal news release.

"If physicians are able to identify individuals who are prone to develop CTNNB1-negative cancer, then it would be possible to strongly recommend physical activity," Ogino added.

The findings also suggest that CTNNB1 could be a potential target for drugs to prevent and treat colorectal cancer in certain patients, Ogino said.

More information

The American Cancer Society has more about colorectal cancer.

-- Robert Preidt

SOURCE: Cancer Research, news release, Feb. 26, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Obesity, physical inactivity linked with risk for certain molecular subtype of colorectal cancer
2. Outdoor Fast-Food Ads Linked to Obesity, Study Suggests
3. Obesity, excess weight gain during pregnancy linked to heavier babies in African-American women
4. Researchers identify role for protein linked to obesity, type 2 diabetes
5. Use Social Media to Fight Childhood Obesity, Heart Experts Say
6. Study Supports Link Between Obesity, Cavities in Homeless Kids
7. In obesity, a micro-RNA causes metabolic problems
8. What babies eat after birth likely determines lifetime risk of obesity, rat study suggests
9. Obesity, larger waist size associated with better outcomes in heart failure patients
10. Wayne State University researcher seeks to understand link between obesity, flu severity
11. Obesity, A Contributing Cause Of Arthritis Of The Knee, Is Now Being Treated With Regenerative Medicine At The Center For Regenerative Medicine
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Obesity, Exercise May Affect Risk for Key Type of Colon Cancer
(Date:3/27/2017)... ... , ... Harris Communications, Inc., a leading provider of assistive technology for ... Deaf Seniors of America Conference, April 4-7 at the Hotel Westin Galleria in Houston. ... staff from Harris Communications and to try out the newest assistive devices available to ...
(Date:3/25/2017)... ... , ... Getting earned media coverage meaningful for Garden Media Group's clients is ... year, Garden Media aims to provide material helpful to clients’ goals and bottom lines. ... key messages to gain coveted media placements, Garden Media wows clients year-round. , ...
(Date:3/24/2017)... (PRWEB) , ... March 24, 2017 , ... ... solutions for contaminated soil, dredged material, and hazardous and non-hazardous materials announced today ... Allentown, Pennsylvania. This acquisition will add four additional processing facilities and a ...
(Date:3/24/2017)... ... March 24, 2017 , ... Mediaplanet today ... conversation on the current obstacles facing infection prevention and offer strategies for the ... by these infections. , The print component of “Fighting Infection” is distributed ...
(Date:3/24/2017)... ... March 24, 2017 , ... Digital Scientists, a software innovation lab specializing in ... a Greenville, South Carolina location. The lab has set up shop at ... been working with South Carolina clients for years from our office here in Atlanta,” ...
Breaking Medicine News(10 mins):
(Date:3/27/2017)... and BOSTON , March 27, ... global pharmaceutical company and Paratek Pharmaceuticals, Inc. (Nasdaq: ... and commercialization of innovative therapies based upon tetracycline ... of sarecycline for the treatment of moderate to ... endpoints. Sarecycline is a once-daily, oral, narrow spectrum ...
(Date:3/27/2017)... 27, 2017  PhaseRx, Inc. (NASDAQ: PZRX), a ... liver diseases in children, today reported financial results ... December 31, 2016 and provided an update on ... to make progress during the fourth quarter of ... our non-human primate safety study, and with our lead ...
(Date:3/24/2017)... , Mar 24, 2017 Research ... Therapy Manufacturing Market, 2017-2027" report to their offering. ... The Cell ... the rapidly growing market of cell therapy manufacturing and focuses ... manufacturing facilities. These therapies are anticipated to emerge as viable ...
Breaking Medicine Technology: