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OROS(R) Methylphenidate in Adults with ADHD: New Insights
Date:5/7/2008

ome. Abuse of methylphenidate may lead to dependence. Tell your health care professional if your child has had problems with alcohol or drugs, has had depression, abnormal thoughts or visions, bipolar disorder, seizures, high blood pressure or has had any heart problems or defects. If your child develops abnormal thinking or hallucinations, abnormal, extreme moods and/or excessive activity, or if aggressive behavior or hostility develops or worsens while taking OROS(R) MPH, consult your health care professional. The most common adverse events reported in children receiving up to 54 mg were headache, upper respiratory tract infection and abdominal pain. The most common adverse events reported by adolescents receiving up to 72 mg were headache, accidental injury and insomnia.

Johnson & Johnson Pharmaceutical Research & Development, LLC (J&JPRD) is part of Johnson & Johnson, the world's most broadly based producer of healthcare products. J&JPRD is headquartered in Raritan, NJ, and has facilities throughout Asia, Europe and the United States. J&JPRD is leveraging drug discovery and drug development in a variety of therapeutic areas to address unmet medical needs worldwide.

McNeil Pediatrics(TM), Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc., is committed to meeting the needs of pediatric medicine through the development of therapies specifically formulated for children. McNeil Pediatrics(TM) markets OROS(R) methylphenidate HCL for treatment of children and adolescents with ADHD in the US. McNeil Pediatrics(TM) is continuing to explore other new therapies to meet the special needs of children and the pediatric community. Visit http://www.mcneilpediatrics.net/ for more information.

OROS(R) is a registered trademark of ALZA Corporation.

1: Kessler RC et al, Journal of American Occupational Environmental

Medicine 2005

2: Kessler RC, Adler L, Barkley R, et
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SOURCE McNeil Pediatrics(TM), Division of Ortho-McNeil-Janssen
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