Navigation Links
ORNL's awake imaging device moves diagnostics field forward
Date:4/4/2013

A technology being developed at Oak Ridge National Laboratory promises to provide clear images of the brains of children, the elderly and people with Parkinson's and other diseases without the use of uncomfortable or intrusive restraints.

Awake imaging provides motion compensation reconstruction, which removes blur caused by motion, allowing physicians to get a transparent picture of the functioning brain without anesthetics that can mask conditions and alter test results. The use of anesthetics, patient restraints or both is not ideal because they can trigger brain activities that may alter the normal brain functions being studied.

With this new capability, researchers hope to better understand brain development in babies, pre-teens and teen-agers. In addition, they believe the technology will provide unprecedented insight into conditions such as autism, drug addictions, alcoholism, traumatic brain injuries and Alzheimer's disease.

"With this work, we're hoping to establish a new paradigm in noninvasive diagnostic imaging," said Justin Baba, a biomedical engineer who heads the ORNL development team.

The study, which was performed in collaboration with Thomas Jefferson National Accelerator Laboratory and Johns Hopkins University, utilized an awake imaging scanner and awake, unanesthetized, unrestrained mice that had been injected with a radiotracer known as DaTSCAN, provided by GE-Medical.

With awake imaging using DaTSCAN and other molecular probes, Baba and colleagues envision development of new, more effective therapies for a wide assortment of conditions and diseases while also contributing to pharmaceutical drug discovery, development and testing. The technology could also help with real-time stabilization and registration of targets during surgical intervention.

Baba noted that this technical accomplishment, detailed in a paper published in The Journal of Nuclear Medicine, has its origins in past Department of Energy-supported research on biomedical imaging. The paper is titled "Conscious, Unrestrained Molecular Imaging of Mice with AwakeSPECT." Jim Goddard of ORNL's Measurement Science and Systems Engineering Division is a co-author.

While a working prototype scanner is located at Johns Hopkins School of Medicine, ORNL is pursuing commercialization of the technology.


'/>"/>

Contact: Ron Walli
wallira@ornl.gov
865-576-0226
DOE/Oak Ridge National Laboratory
Source:Eurekalert

Related medicine news :

1. Violent TV Shows Keep Young Kids Awake: Study
2. Traffic May Keep City Dwellers Awake, Harming Health
3. Subcortical damage is primary cause of neurological deficits after awake craniotomy
4. Anesthesiologist reveals unique tactic to calm young patient during awake craniotomy
5. Live imaging shows response to cancer drugs can be boosted by altering tumor microenvironment
6. MR enterography is as good or better than standard imaging exams for pediatric Crohns patients
7. Use of dedicated pediatric imaging departments for pediatric CT reduces radiation dose
8. Low-dose whole-body CT finds disease missed on standard imaging for patients with multiple myeloma
9. Study examines necessity of additional imaging in PET/CT oncologic reports
10. Fox Chase researchers find no disparities in imaging before breast cancer surgery
11. Piramal imaging to present data at Society for Nuclear Medicine Annual Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/21/2017)... ... April 21, 2017 , ... The adage “Show, don’t tell” applies perfectly ... in the company’s esteemed VISION House demonstration project series. Manifesting the concept of right-sized ... resources they need to live affordably and abundantly without unduly taxing the resources of ...
(Date:4/21/2017)... ... April 21, 2017 , ... The Hong Kong Polytechnic University ... printing facility among higher education institutions in Hong Kong to support teaching, learning and ... the range and quantity of facilities in Hong Kong. , With an area ...
(Date:4/21/2017)... ... April 21, 2017 , ... Alive for Wellness is a group ... mental health struggles. The Alive team uses advanced behavioral sciences treatment modalities to ... with a mental health struggle is based on 10 modalities of treatment ...
(Date:4/21/2017)... ... April 21, 2017 , ... ... category of International Trade, the UK’s most prestigious award for business success. ... 95% of total revenues and has grown by a total of 400% over ...
(Date:4/21/2017)... ... , ... BrightStar Care Salt Lake City, a home care agency that also ... has appointed Rex Wheeler as its new Director of Business Development. “This partnership helps ... ability to provide quality care to the community,” said Tammara Brown, owner of BrightStar ...
Breaking Medicine News(10 mins):
(Date:4/18/2017)... , April 18, 2017 Viverae ® ... to announce the integration of IBM ® Watson ... to deliver targeted communications for a personalized experience. Through ... actions on their health in real time. The enhanced ... matter most to members, wherever they are in their ...
(Date:4/18/2017)... 2017  Astute Medical, Inc., developer of biomarkers for ... presented at the 2017 National Kidney Foundation (NKF) ... through April 22. Physicians will present data on two ... risk for acute kidney injury (AKI) during the management ... Elevated levels of TIMP-2 and IGFBP-7 have ...
(Date:4/18/2017)... SUNNYVALE, Calif. , April 18, 2017 /PRNewswire/ ... results of collaboration started in 2016, in which ... "Artificial Brain SOINN". The companies achieved initial results ... ultrasound solution by Artificial Brain SOINN. The results ... Tokyo Big Sight, April 19-21, at booths 4505 ...
Breaking Medicine Technology: