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OHSU research team joins elite consortium dedicated to curing type 1 diabetes
Date:9/15/2010

ouse model. However, it is not yet know which liver cells can best be transformed into beta cells, and existing methods for growing liver cells in tissue culture are not well developed, according to Grompe.

With the support of this and similar grants, Grompe and colleagues are working to determine which type of liver cell is most easily converted and perfecting their methods of growing them in tissue culture. In addition, they are exploring the potential for harvesting and manipulating cells from novel sources, including the gall bladder.

"We have found that human gall bladder cells, which are very similar to the cells within the liver, can be grown and expanded in tissue culture very easily. It is a very promising source of reprogrammable beta cells," explained Grompe, who also is a professor of pediatrics and molecular and medical genetics in the OHSU School of Medicine, OHSU Doernbecher Children's Hospital.


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Contact: Tamara Hargens-Bradley
hargenst@ohsu.edu
503-494-8231
Oregon Health & Science University
Source:Eurekalert

Page: 1 2

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