Navigation Links
OHSU is part of national effort to preserve, restore fertility in women with cancer
Date:9/11/2007

Portland, Ore. - The Oregon National Primate Research Center and the Oregon Health & Science University School of Medicine have been named to a national team of institutions hoping to preserve or restore fertility in women battling cancer. The Oncofertility Consortium, funded for five years by the National Institutes of Health, features participants from five universities and comprises researchers, physicians, engineers, educators, social workers and medical ethicists.

Biomedical research has helped save the lives of many women battling cancer, explained Richard Stouffer, Ph.D., director of the research team at OHSU. Stouffer also directs ONPRCs reproductive sciences division and is a professor of obstetrics and gynecology in the OHSU School of Medicine. However, the powerful chemotherapy drugs and radiation used to beat cancer can also result in a loss of reproductive function, which is a tremendous blow to young cancer patients who hope to have children. The bottom-line goal for this research team across the United States is to help these women through various avenues including research, treatment and counseling.

Additional members of the OHSU research team include Mary Zelinski, Ph.D., an affiliate assistant scientist at ONPRC, and David Lee, M.D., an assistant professor of obstetrics and gynecology, reproductive endocrinology and infertility in the OHSU School of Medicine.

Together the scientists are working on methods for restoring fertility in cancer patients by studying rhesus macaque monkeys who have reproductive systems very similar to humans. Specifically, the team is hoping to gain additional understanding about the growth of follicles in the ovaries and either to preserve or restart this function. Follicle growth is necessary for the development of oocytes (fertile eggs) in the ovaries.

Past research has demonstrated that cancer therapies often destroy follicles in the ovaries, thereby reducing fertility. Working with researchers at Northwestern University and University of Missouri-Columbia, the OHSU group will investigate methods to freeze and store monkey ovary tissue and, following thawing, to grow follicles in culture or to promote follicle growth after transplantation back into the monkey.

In 2004 Lee and colleagues published results in the journal Nature demonstrating great strides in re-establishing fertility in a rhesus macaque monkey after ovarian tissue transplantation that resulted in a successful birth. This research aims to build upon these earlier findings.

Because this is a relatively new field, OHSU is home to one of the only fertility preservation programs in the country, explained Lee, who serves as director of the OHSU Fertile Future Program. Past fertility research milestones at OHSU include our research in monkeys who underwent ovarian tissue transplantation and also human studies such as the first human pregnancy from frozen-thawed eggs.

While the Oregon researchers conduct their research, other team members at the University of California, San Diego; the University of Pennsylvania, the University of Missouri-Columbia and the lead institution: Northwestern University will conduct additional studies. These studies will relate to preserving reproductive tissues for future transplantation, studying human follicles, and global and social studies of the oncofertility issue. Additional information on these studies and the educational opportunities in the consortium can be located at the research teams Web site: http://oncofertility.northwestern.edu/


'/>"/>

Contact: Jim Newman
newmanj@ohsu.edu
503-494-8231
Oregon Health & Science University
Source:Eurekalert

Related medicine news :

1. International community warns India on HIV situation
2. Mexico and US border attain a new outlook due to BiNational Sustainability Laboratory
3. National Lung Study in the process
4. Indian Nationals with Foreign Medical Degrees can now practice in India
5. Key step forward on International Health Rules
6. ICMR along with other International Research organisation with drug development for Neglected Diseases
7. International Osteoporosis Research Centre To Be Started In India.
8. Hepatitis B Vaccine To Be Included In National Immunization Programme
9. Indian hospitals require International Accreditation
10. International Conference On Malaria - Laveran To Genomics
11. UK Govt Says On Course For National Chlamydia Screening
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a ... has been awarded a contract by the Center for Medicare and Medicaid Services ... accelerate the enterprise use of Agile methodologies in a consistent and high value ...
(Date:10/12/2017)... San Francisco, CA (PRWEB) , ... October 12, ... ... and Dr. Cheng, are now treating sleep apnea using cutting-edge Oventus ... sleep apnea, a serious sleep disorder characterized by frequent cessation in breathing. Oral ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of ... Carol Friedman, PhD, FACMI, during the Opening Session of AMIA’s Annual Symposium in Washington, ... In honor of Morris F. Collen, a pioneer in the field of medical informatics, ...
(Date:10/12/2017)... ... October 12, 2017 , ... HMP , a leader in healthcare events ... Magazine Eddie Digital Award for ‘Best B-to-B Healthcare Website.’ Winners were announced during the ... The annual award competition recognizes editorial and design excellence across a range of sectors. ...
(Date:10/12/2017)... ... October 12, 2017 , ... Health Literacy Innovations (HLI), ... software tool, and the Cancer Patient Education Network (CPEN), an independent professional organization ... a new strategic alliance. , As CPEN’s strategic partner, HLI will help ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... 2, 2017  Eli Lilly and Company (NYSE: ... the third quarter of 2017 on Tuesday, October 24, ... that day with the investment community and media to ... conference call will begin at 9 a.m. Eastern time. ... live webcast of the conference call through a link ...
(Date:9/28/2017)... 28, 2017 Cohen Veterans Bioscience and Early ... of wearable and home sensors for real-time monitoring of ... Foundation, a nonprofit organization focused on disruptive health solutions ... affordable analytical system to record and integrate behavioral, cognitive, ... ...
(Date:9/23/2017)... Pa. , Sept. 22, 2017 Janssen ... a complete response letter from the U.S. Food and ... seeking approval of sirukumab for the treatment of moderately ... letter indicates additional clinical data are needed to further ... moderately to severely active RA. ...
Breaking Medicine Technology: