Navigation Links
OHSU is part of national effort to preserve, restore fertility in women with cancer
Date:9/11/2007

Portland, Ore. - The Oregon National Primate Research Center and the Oregon Health & Science University School of Medicine have been named to a national team of institutions hoping to preserve or restore fertility in women battling cancer. The Oncofertility Consortium, funded for five years by the National Institutes of Health, features participants from five universities and comprises researchers, physicians, engineers, educators, social workers and medical ethicists.

Biomedical research has helped save the lives of many women battling cancer, explained Richard Stouffer, Ph.D., director of the research team at OHSU. Stouffer also directs ONPRCs reproductive sciences division and is a professor of obstetrics and gynecology in the OHSU School of Medicine. However, the powerful chemotherapy drugs and radiation used to beat cancer can also result in a loss of reproductive function, which is a tremendous blow to young cancer patients who hope to have children. The bottom-line goal for this research team across the United States is to help these women through various avenues including research, treatment and counseling.

Additional members of the OHSU research team include Mary Zelinski, Ph.D., an affiliate assistant scientist at ONPRC, and David Lee, M.D., an assistant professor of obstetrics and gynecology, reproductive endocrinology and infertility in the OHSU School of Medicine.

Together the scientists are working on methods for restoring fertility in cancer patients by studying rhesus macaque monkeys who have reproductive systems very similar to humans. Specifically, the team is hoping to gain additional understanding about the growth of follicles in the ovaries and either to preserve or restart this function. Follicle growth is necessary for the development of oocytes (fertile eggs) in the ovaries.

Past research has demonstrated that cancer therapies often destroy follicles in the ovaries, thereby reducing fertility. Working with researchers at Northwestern University and University of Missouri-Columbia, the OHSU group will investigate methods to freeze and store monkey ovary tissue and, following thawing, to grow follicles in culture or to promote follicle growth after transplantation back into the monkey.

In 2004 Lee and colleagues published results in the journal Nature demonstrating great strides in re-establishing fertility in a rhesus macaque monkey after ovarian tissue transplantation that resulted in a successful birth. This research aims to build upon these earlier findings.

Because this is a relatively new field, OHSU is home to one of the only fertility preservation programs in the country, explained Lee, who serves as director of the OHSU Fertile Future Program. Past fertility research milestones at OHSU include our research in monkeys who underwent ovarian tissue transplantation and also human studies such as the first human pregnancy from frozen-thawed eggs.

While the Oregon researchers conduct their research, other team members at the University of California, San Diego; the University of Pennsylvania, the University of Missouri-Columbia and the lead institution: Northwestern University will conduct additional studies. These studies will relate to preserving reproductive tissues for future transplantation, studying human follicles, and global and social studies of the oncofertility issue. Additional information on these studies and the educational opportunities in the consortium can be located at the research teams Web site: http://oncofertility.northwestern.edu/


'/>"/>

Contact: Jim Newman
newmanj@ohsu.edu
503-494-8231
Oregon Health & Science University
Source:Eurekalert

Related medicine news :

1. International community warns India on HIV situation
2. Mexico and US border attain a new outlook due to BiNational Sustainability Laboratory
3. National Lung Study in the process
4. Indian Nationals with Foreign Medical Degrees can now practice in India
5. Key step forward on International Health Rules
6. ICMR along with other International Research organisation with drug development for Neglected Diseases
7. International Osteoporosis Research Centre To Be Started In India.
8. Hepatitis B Vaccine To Be Included In National Immunization Programme
9. Indian hospitals require International Accreditation
10. International Conference On Malaria - Laveran To Genomics
11. UK Govt Says On Course For National Chlamydia Screening
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... June 25, 2016 , ... ... issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the ... several important health care topics including advance care planning, healthcare costs and patient ...
(Date:6/25/2016)... , ... June 25, 2016 , ... "With 30 hand-drawn ... specific project," said Christina Austin - CEO of Pixel Film Studios. , ProHand ... all within Final Cut Pro X . Simply select a ProHand generator and ...
(Date:6/25/2016)... ... 25, 2016 , ... Dr. Calvin Johnson has dedicated his ... implemented orthobiologic procedures as a method for treating his patients. The procedure is ... to perform the treatment. Orthobiologics are substances that orthopaedic surgeons use to help ...
(Date:6/24/2016)... , ... June 24, 2016 , ... A recent ... most people are unfamiliar with. The article goes on to state that individuals are ... many of these less common operations such as calf and cheek reduction. The Los ...
(Date:6/24/2016)... ... , ... Marcy was in a crisis. Her son James, eight, was out of control. Prone ... physically. , “When something upset him, he couldn’t control his emotions,” remembers Marcy. “If ... at my other children and say he was going to kill them. If we ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016  Consumers have taken ... regulators/payers have placed more emphasis on patient outcomes. ... support programs in the pharmaceutical industry have evolved ... Consequently, pharmaceutical companies are focusing on becoming more ... providing products and services that improve health. ...
(Date:6/24/2016)... SAN FRANCISCO, Calif. , June 24, 2016 ... GBT ), a biopharmaceutical company developing novel therapeutics ... significant unmet needs, today announced the closing of ... shares of common stock, at the public offering ... shares in the offering were offered by GBT. ...
(Date:6/24/2016)... 2016 Dublin ... addition of the " Global Markets for Spectroscopy ... This report focuses on the ... review, including its applications in various applications. The report ... includes three main industries: pharmaceutical and biotechnology, food and ...
Breaking Medicine Technology: