Navigation Links
OHSU School of Dentistry uncovers mechanism for dental pain
Date:1/8/2009

PORTLAND, Ore. Researchers at Oregon Health & Science University's School of Dentistry (www.ohsu.edu/sod) have discovered a novel function of the peptide known as Nerve Growth Factor (NGF) in the development of the trigeminal nerve. The trigeminal nerve provides the signaling pathway for periodontal pain, dental surgical pain, and pain associated with temporomandibular disorder, trigeminal neuralgia, migraine, and other neuropathic and inflammatory conditions.

The study is posted online (www.neuropeptidesjournal.com/article/S0143-4179(08)00110-8/abstract) in the journal Neuropeptides and will appear in print issues of that journal in early 2009.

Working with researchers in the dental school departments of Endodontology and Integrative Biosciences, second-year endodontology resident and lead author of the study, Leila Tarsa, D.D.S., M.S., found a new mechanism involved in establishing junctions known as synapses between trigeminal nerve cells. Nerve cells communicate with one another through chemicals called transmitters that are released at synapses. The transmitter release from nerve cells endings is possible only if aided by several molecules that are critical for proper function of the synapse. Tarsa's research shows that NGF promotes transport of one of the molecules (called synaptophysin) from the nerve cell body to its ending.

"The data indicate that NGF participates in formation of neuronal connections in the trigeminal system," said Agnieszka Balkowiec, M.D., Ph.D., OHSU School of Dentistry assistant professor of integrative biosciences and OHSU School of Medicine adjunct assistant professor of physiology and pharmacology, who is the senior author of the study and whose lab hosted the research. "This study has broad implications for trigeminal nerve regeneration."


'/>"/>

Contact: Sydney Clevenger
clevenge@ohsu.edu
503-418-1792
Oregon Health & Science University
Source:Eurekalert

Page: 1

Related medicine news :

1. OHSU School of Dentistry team discovers new molecule in blood-pressure control system
2. New York Schools Receive Program for Children with Autism
3. National Association of Therapeutic Schools and Programs Announces New Executive Director
4. Kaiser Permanente Provides Seed Funding to the Institute for Healthcare Improvements New Open School for Health Professions
5. BMC, Boston University School of Medicine dermatologist named one of Americas Top Doctors
6. BMC, Boston University School of Medicine cardiologist named 1 of Americas Top Doctors
7. Augsburg: Weight issues in children starting school
8. Limiting School Snacks Boosts Fruit, Veggie Consumption
9. New Strategies for the New Year: Resolving to break an addiction? Help from Harvard Medical School
10. School Program Helps Cut Asthma Risks
11. Sharing The Arts & Ridgewood High School Present Musical Production of Charlie and The Chocolate Factory
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/28/2015)... Early surgery may not be the best ... injuries, according to new research from Tripler Army Medical ... Society for Sports Medicine’s ( AOSSM ) Specialty Day, ... was not performed. , The final study group focused ... 17 receiving non-surgical therapy. Of the non-surgery group, 8 ...
(Date:3/28/2015)... March 28, 2015 Aureus Medical ... staffing, including physical therapy jobs, has announced that ... Ohio Physical Therapy Association Annual Conference to be ... Downtown Hotel in Columbus, OH. , The ... and exhibits with products and services. , ...
(Date:3/28/2015)... ARDX will sponsor the 7th Annual Women’s Wellness Celebration on ... Center in Chesapeake, Virginia. Each year, ARDX celebrates Women’s ... the Hampton Roads region. The 2015 Women’s History Month ... grow stronger through sharing their stories and learning the strategies ... theme is T-talk where we will share a cup of ...
(Date:3/27/2015)... 2015 The Monogamy Method ... Samantha Sanderson and Jason Rogers has just been released ... attention. The commotion surrounding the course's launch has caught ... publish an in-depth review of the new program. , ... in their lives suddenly start pulling away or expressing ...
(Date:3/27/2015)... New York (PRWEB) March 27, 2015 ... http://www.lipitorlawsuitcenter.com/ ) that allege the statin medication increases the ... has granted Pfizer Inc.’s Motion to Dismiss four individual ... to a Case Management Order issued in the U.S. ... the Court determined that the dismissals were warranted because ...
Breaking Medicine News(10 mins):Health News:For Type V AC Joint Injuries, Early Surgery May Not Be the Best Approach 2Health News:Healthcare Staffing Leader, Aureus Medical Group, to Exhibit at the Ohio Physical Therapy Association Annual Conference 2Health News:The Monogamy Method - Review Of Samantha Sanderson & Jason Rogers' Relationship Program Released 2Health News:Lipitor Lawsuits Move Forward in Federal Multidistrict Litigation, as Court Rules on Pfizer’s Motion to Dismiss Certain Cases 2Health News:Lipitor Lawsuits Move Forward in Federal Multidistrict Litigation, as Court Rules on Pfizer’s Motion to Dismiss Certain Cases 3
... don,t take candy from strangers, expert says , , FRIDAY, ... the corner, many parents are wondering how they can ... Meridith Sonnett, director of pediatric emergency services at Morgan ... precautions can help make Halloween a happy and safe ...
... Plan Options Provide Seniors with Affordable Access to Brand ... R.I., Oct. 31 SilverScript Insurance,Company, a subsidiary of ... it,will continue to offer a variety of Medicare Prescription ... regions and Puerto Rico. Medicare,beneficiaries can choose from three ...
... Intercim LLC, a global,leader in manufacturing and ... regulated industries, announced today,that Memko, an Australian-based organization ... defense industry, will resell its,Pertinence Suite powered by ... As Intercim President and CEO John Todd notes, ...
... - Q3 2008 Revenue of $49 million (+30%y/y), EPS $0.23 (+44% y/y) ... from $0.75 (+35% y/y) ... EPS Guidance of $0.96, NEW YORK, Oct. 31 HMS Holdings ... 2008., Third Quarter Results, For the quarter ended September 30, ...
... MD, noted medical researcher, clinical nutritionist and women,s health practitioner has ... to do something this holiday season--volunteer, contribute to a charity, or ... , ... Potomac, MD (PRWEB) October 31, 2008 -- ...
... doctor looks at a squiggly-lined graph to determine the ... help the doctor decide whether you,re having a heart ... Correct interpretation may prompt life-saving, emergency measures; incorrect interpretation ... no uniform way to teach doctors in training how ...
Cached Medicine News:Health News:Family Halloween Safety Can Be Fiendishly Simple 2Health News:SilverScript Insurance Company, a CVS Caremark Company, Provides Variety of Medicare Prescription Drug Plan Options for 2009 2Health News:SilverScript Insurance Company, a CVS Caremark Company, Provides Variety of Medicare Prescription Drug Plan Options for 2009 3Health News:Intercim Announces Australia-Based Memko to Resell its Pertinence Suite Powered by Velocity in Asia Pacific 2Health News:HMS Holdings Corp. Announces Q3 2008 Results, 2008 Revised Guidance and Initial 2009 Guidance 2Health News:HMS Holdings Corp. Announces Q3 2008 Results, 2008 Revised Guidance and Initial 2009 Guidance 3Health News:HMS Holdings Corp. Announces Q3 2008 Results, 2008 Revised Guidance and Initial 2009 Guidance 4Health News:HMS Holdings Corp. Announces Q3 2008 Results, 2008 Revised Guidance and Initial 2009 Guidance 5Health News:HMS Holdings Corp. Announces Q3 2008 Results, 2008 Revised Guidance and Initial 2009 Guidance 6Health News:HMS Holdings Corp. Announces Q3 2008 Results, 2008 Revised Guidance and Initial 2009 Guidance 7Health News:HMS Holdings Corp. Announces Q3 2008 Results, 2008 Revised Guidance and Initial 2009 Guidance 8Health News:HMS Holdings Corp. Announces Q3 2008 Results, 2008 Revised Guidance and Initial 2009 Guidance 9Health News:HMS Holdings Corp. Announces Q3 2008 Results, 2008 Revised Guidance and Initial 2009 Guidance 10Health News:Susan Lark, MD Says "Volunteer" Your Way to Good Health this Holiday Season 2Health News:Susan Lark, MD Says "Volunteer" Your Way to Good Health this Holiday Season 3Health News:Can your doctor correctly read a critical heart test? 2Health News:Can your doctor correctly read a critical heart test? 3
(Date:3/27/2015)... The Temple Health & Bioscience District (THBD) today announced it ... South First St. in the Temple Medical and Education District ... of Temple to receive funding for redevelopment. Located ... Health Care System, the new facility will enable THBD to ... life science companies. Temple ...
(Date:3/27/2015)... 27, 2015 XRpro Sciences, Inc., a ... and development services which features high throughput transporter ... announced financial results for the year ended December ... Chairman of XRpro Sciences commented, "We have completed ... development stage to commercial stage in large part ...
(Date:3/27/2015)... March 27, 2015 As of February, ... incontinence devices for women. "Shipping thousands ... gratifying part is the hundreds of letters, emails ... lives have been positively impacted by our technology," ... InControl recently released Apex, an over-the-counter ...
Breaking Medicine Technology:Temple Health & Bioscience District Relocates, Offers Office And Lab Space To Biotech Companies 2XRpro Sciences Announces Fiscal 2014 Financial Results 2XRpro Sciences Announces Fiscal 2014 Financial Results 3XRpro Sciences Announces Fiscal 2014 Financial Results 4InControl Medical Surpasses 40,000 Shipments Of Incontinence Devices For Women 2
... Rigel Pharmaceuticals, Inc. (Nasdaq: RIGL ) today reported financial ... For the first quarter of 2011, Rigel reported a net loss ... loss of $22.3 million, or $0.43 per share, in the first ... of 2011 and 2010 were 52.3 million and 52.0 million, respectively. ...
... 3, 2011 Delcath Systems, Inc. (Nasdaq: DCTH ... the newly created position of Executive Vice President, Global Operations. ... and operations team, and will implement logistics and supply chain ... later this year. Mr. Mapes will report directly to Eamonn ...
Cached Medicine Technology:Rigel Announces First Quarter Financial Results 2Rigel Announces First Quarter Financial Results 3Rigel Announces First Quarter Financial Results 4Delcath Names Harold C. Mapes as Executive Vice President of Global Operations 2Delcath Names Harold C. Mapes as Executive Vice President of Global Operations 3
The ALB method used on the Dimension clinical chemistry system is an in vitro diagnostic test intended for the quantitative determination of albumin in serum...
For the quantitative in vitro determination of creatinine in serum, plasma or urine....
The PHOS method used on the Dimension clinical chemistry system is an in vitro diagnostic test intended for the quantitative determination of phosphorus in serum....
The TBIL method used on the Dimension clinical chemistry system is an in vitro diagnostic test intended for the quantitative determination of total bilirubin in serum and plasma...
Medicine Products: