Navigation Links
OHSU School of Dentistry uncovers mechanism for dental pain
Date:1/8/2009

PORTLAND, Ore. Researchers at Oregon Health & Science University's School of Dentistry (www.ohsu.edu/sod) have discovered a novel function of the peptide known as Nerve Growth Factor (NGF) in the development of the trigeminal nerve. The trigeminal nerve provides the signaling pathway for periodontal pain, dental surgical pain, and pain associated with temporomandibular disorder, trigeminal neuralgia, migraine, and other neuropathic and inflammatory conditions.

The study is posted online (www.neuropeptidesjournal.com/article/S0143-4179(08)00110-8/abstract) in the journal Neuropeptides and will appear in print issues of that journal in early 2009.

Working with researchers in the dental school departments of Endodontology and Integrative Biosciences, second-year endodontology resident and lead author of the study, Leila Tarsa, D.D.S., M.S., found a new mechanism involved in establishing junctions known as synapses between trigeminal nerve cells. Nerve cells communicate with one another through chemicals called transmitters that are released at synapses. The transmitter release from nerve cells endings is possible only if aided by several molecules that are critical for proper function of the synapse. Tarsa's research shows that NGF promotes transport of one of the molecules (called synaptophysin) from the nerve cell body to its ending.

"The data indicate that NGF participates in formation of neuronal connections in the trigeminal system," said Agnieszka Balkowiec, M.D., Ph.D., OHSU School of Dentistry assistant professor of integrative biosciences and OHSU School of Medicine adjunct assistant professor of physiology and pharmacology, who is the senior author of the study and whose lab hosted the research. "This study has broad implications for trigeminal nerve regeneration."


'/>"/>

Contact: Sydney Clevenger
clevenge@ohsu.edu
503-418-1792
Oregon Health & Science University
Source:Eurekalert

Page: 1

Related medicine news :

1. OHSU School of Dentistry team discovers new molecule in blood-pressure control system
2. New York Schools Receive Program for Children with Autism
3. National Association of Therapeutic Schools and Programs Announces New Executive Director
4. Kaiser Permanente Provides Seed Funding to the Institute for Healthcare Improvements New Open School for Health Professions
5. BMC, Boston University School of Medicine dermatologist named one of Americas Top Doctors
6. BMC, Boston University School of Medicine cardiologist named 1 of Americas Top Doctors
7. Augsburg: Weight issues in children starting school
8. Limiting School Snacks Boosts Fruit, Veggie Consumption
9. New Strategies for the New Year: Resolving to break an addiction? Help from Harvard Medical School
10. School Program Helps Cut Asthma Risks
11. Sharing The Arts & Ridgewood High School Present Musical Production of Charlie and The Chocolate Factory
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... NY (PRWEB) September 20, 2014 As summer ... Krishnan DMD in Queens, NY now reminds area patients about ... than 80% of our population affected by gum disease, there ... longer.” , For over 20 years Dr. Krishnan has treated ... Hills office location. “Most patients that come in due to ...
(Date:9/19/2014)... collaborative research team led by Medical College of Wisconsin (MCW) ... and insulin levels in rats, mice and in humans. The ... Genetics . , Leah Solberg Woods, Ph.D., associate ... Children,s Hospital of Wisconsin Research Institute, led the study and ... of the paper identified a gene called Tpcn2 in which ...
(Date:9/19/2014)... Albany,NY (PRWEB) September 19, 2014 ... Dr. Reed Ference, is excited to announce the ... with periodontal disease, gingivitis and those needing dental ... the LANAP® laser treatment removes the fear factor ... no stitches, less discomfort and bleeding make, this ...
(Date:9/19/2014)... 2014 York University researchers say a simple ... to detect heightened risk for developing Alzheimer,s disease ... telltale behavioural signs of dementia., Faculty of Health ... who led the study asked the participants to ... on dual screen laptop computers. The test aimed ...
(Date:9/19/2014)... 2014 Recent financial data reveled ... increased their sales by 7% in the last quarter ... industry can be used as a bellwether to determine ... This data has been proven to show trends with ... transportation. Other non-trucking data is largely influenced by international ...
Breaking Medicine News(10 mins):Health News:New York Periodontist Dr. Prabha Krishnan Now Raises Awareness about the Dangers of Untreated Decay, Gingivitis and Gum Disease During Self-Awareness Month 2Health News:New York Periodontist Dr. Prabha Krishnan Now Raises Awareness about the Dangers of Untreated Decay, Gingivitis and Gum Disease During Self-Awareness Month 3Health News:Albany, NY Periodontist Reed Ference, DMD, Calms Fears of Patients with Gum Disease by Offering LANAP®, An Advanced, Less Invasive Treatment Solution 2Health News:Albany, NY Periodontist Reed Ference, DMD, Calms Fears of Patients with Gum Disease by Offering LANAP®, An Advanced, Less Invasive Treatment Solution 3Health News:Simple test can help detect Alzheimer's before dementia signs show: York U study 2Health News:LeaseQ Announces Good News For The Truck Leasing Industry As Truck Rentals In The U.S Continues to Gain Traction 2Health News:LeaseQ Announces Good News For The Truck Leasing Industry As Truck Rentals In The U.S Continues to Gain Traction 3
... survey conducted in US in 2002 and observed that half of ... have had previous ones earlier. ,Women who had come ... 30, were from a large family and with low income. Most ... conceived in spite of it. ,Abortions are not uncommon ...
... South Korea has caused Japan to temporarily suspend the ... around 6000 chickens have died as a result of ... outbreak have been sought from South Korea. "As a ... Korean poultry", Chief Cabinet Secretary Yasuhisa Shiozaki of Japan ...
... of botulism following cosmetic injections to the face indicates ... that resulted in toxin levels up to 40 times ... ,Botulism is a rare paralytic illness caused by ... toxin-producing strains of Clostridium baratii and Clostridium butyricum. Botulism, ...
... a cheap and simple way of cutting heart disease ... to a study by heart experts, folic acid could ... blood considered to be a cause of cardiovascular disease, ... from the London School of Medicine and Barts Hospital, ...
... Two recent articles in Science by researchers at Yale School ... the risk of developing //the aggressive 'wet' form of age-related ... people over age 50. ,AMD causes light-sensitive cells ... of central vision. Of the two forms of AMD, the ...
... for Ageing, Senator Santo Santoro, to discuss the issue of ... AMA's Federal Budget Submission 2007-08. ,The current ... difficult for GPs to provide ongoing care to residents of ... Haikerwal, said today the number of general practitioners able to ...
Cached Medicine News:Health News:Highly-Concentrated Botulinum Preparation Can Result in Severe Illness 2Health News:Highly-Concentrated Botulinum Preparation Can Result in Severe Illness 3Health News:Gene Linked With Aggressive 'Wet' Form Of AMD 2
(Date:9/19/2014)... According to market research ... Industrial, & Laboratory), Industry (Food, Pharmaceutical, Biotechnology, Surgical ... & Geography - Global Trends & Forecast to ... lyophilization market on the basis of various types, ... the market size of each of these segments ...
(Date:9/19/2014)... Technologies Corp. (NASDAQ: BSTC ), a biopharmaceutical company ... in the U.S. and XIAPEX ® in the ... will present a corporate overview at the 21 st ... The presentation will take place on Friday, September 26, ... in New York, NY . A live ...
(Date:9/19/2014)... VIENNA , Sept. 19, 2014 ... positive interim clinical data for its lead candidate ITCA ... diabetes patients with high baseline HbA1c levels at the ... for the Study of Diabetes (EASD). Data from the ... reduced levels of blood sugar in patients with poorly ...
Breaking Medicine Technology:Lyophilization Market Worth $5,121.5 Million by 2019 2Lyophilization Market Worth $5,121.5 Million by 2019 3BioSpecifics Technologies Corp. to Present at the 21st Annual BioCentury NewsMakers in the Biotech Industry Conference 2Intarcia Announces Presentation of Phase 3 Data at EASD Showing ITCA 650 Markedly Reduces Blood Sugar In Patients With Poorly Controlled Type 2 Diabetes 2Intarcia Announces Presentation of Phase 3 Data at EASD Showing ITCA 650 Markedly Reduces Blood Sugar In Patients With Poorly Controlled Type 2 Diabetes 3Intarcia Announces Presentation of Phase 3 Data at EASD Showing ITCA 650 Markedly Reduces Blood Sugar In Patients With Poorly Controlled Type 2 Diabetes 4
... General Dynamics Information Technology, a business unit of General ... a contract to support the U.S. Army Medical Department,s ... facilities and transition to newly constructed facilities. The indefinite ... by the U.S. Army Corps of Engineers, has a ...
... Oct. 12 Misonix, Inc. (Nasdaq: MSON ... medical device technology, which worldwide is used for acute ... its non-exclusive distribution arrangement in the United States with ... As a result, Misonix will assume exclusive ...
Cached Medicine Technology:General Dynamics Awarded Contract to Outfit and Transition U.S. Army Medical Facilities 2General Dynamics Awarded Contract to Outfit and Transition U.S. Army Medical Facilities 3Misonix Announces Change in Distribution of SonaStar® Surgical Aspiration System in the U.S. 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: