Navigation Links
OHSU School of Dentistry uncovers mechanism for dental pain
Date:1/8/2009

PORTLAND, Ore. Researchers at Oregon Health & Science University's School of Dentistry (www.ohsu.edu/sod) have discovered a novel function of the peptide known as Nerve Growth Factor (NGF) in the development of the trigeminal nerve. The trigeminal nerve provides the signaling pathway for periodontal pain, dental surgical pain, and pain associated with temporomandibular disorder, trigeminal neuralgia, migraine, and other neuropathic and inflammatory conditions.

The study is posted online (www.neuropeptidesjournal.com/article/S0143-4179(08)00110-8/abstract) in the journal Neuropeptides and will appear in print issues of that journal in early 2009.

Working with researchers in the dental school departments of Endodontology and Integrative Biosciences, second-year endodontology resident and lead author of the study, Leila Tarsa, D.D.S., M.S., found a new mechanism involved in establishing junctions known as synapses between trigeminal nerve cells. Nerve cells communicate with one another through chemicals called transmitters that are released at synapses. The transmitter release from nerve cells endings is possible only if aided by several molecules that are critical for proper function of the synapse. Tarsa's research shows that NGF promotes transport of one of the molecules (called synaptophysin) from the nerve cell body to its ending.

"The data indicate that NGF participates in formation of neuronal connections in the trigeminal system," said Agnieszka Balkowiec, M.D., Ph.D., OHSU School of Dentistry assistant professor of integrative biosciences and OHSU School of Medicine adjunct assistant professor of physiology and pharmacology, who is the senior author of the study and whose lab hosted the research. "This study has broad implications for trigeminal nerve regeneration."


'/>"/>

Contact: Sydney Clevenger
clevenge@ohsu.edu
503-418-1792
Oregon Health & Science University
Source:Eurekalert

Page: 1

Related medicine news :

1. OHSU School of Dentistry team discovers new molecule in blood-pressure control system
2. New York Schools Receive Program for Children with Autism
3. National Association of Therapeutic Schools and Programs Announces New Executive Director
4. Kaiser Permanente Provides Seed Funding to the Institute for Healthcare Improvements New Open School for Health Professions
5. BMC, Boston University School of Medicine dermatologist named one of Americas Top Doctors
6. BMC, Boston University School of Medicine cardiologist named 1 of Americas Top Doctors
7. Augsburg: Weight issues in children starting school
8. Limiting School Snacks Boosts Fruit, Veggie Consumption
9. New Strategies for the New Year: Resolving to break an addiction? Help from Harvard Medical School
10. School Program Helps Cut Asthma Risks
11. Sharing The Arts & Ridgewood High School Present Musical Production of Charlie and The Chocolate Factory
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/28/2016)... ... 2016 , ... After a year and a half of planning the Multiple Pathways of ... Multiple Pathways of Recovery Conference was held May 2 -4, 2016 at the Mystic ... came together to explore the many pathways individuals use to get into and sustain their ...
(Date:5/27/2016)... ... May 27, 2016 , ... Two director-level employees of Horizon Blue Cross Blue ... Industry (TWIN) 2016 honorees. The award recognizes businesswomen who excel in their fields ... Director of the MLTSS (Managed Long-Term Services and Supports) Program at Horizon NJ Health ...
(Date:5/27/2016)... ... , ... This campaign aims to provide a path to improved education and ... and change. , As nearly 795,000 Americans suffering from a new or recurrent stoke ... with an estimated 129,000 of these people dying from stroke, it’s become our nation’s ...
(Date:5/27/2016)... ... 27, 2016 , ... Aimed at nurses and employees in ... courtesy of leaders in the nursing and health care industry. It also provides ... and associations—namely Jones & Bartlett Learning. , Jones & Bartlett Learning is adding ...
(Date:5/26/2016)... ... ... Despite last week’s media reports hinting at a June rate hike after the ... for an interest rate increase, according to Rajeev Dhawan of the Economic Forecasting Center ... Market Committee (FOMC) dot charts are of interest to the press for their noise ...
Breaking Medicine News(10 mins):
(Date:5/27/2016)... PUNE, India , May 27, 2016 ... in the instances of hypertension is driving ambulatory blood ... muscles lose their elasticity and their ability to respond ... blood pressure. This condition can lead to various cardiovascular ... and peripheral vascular disease. These diseases are growing in ...
(Date:5/26/2016)... , May 26, 2016 According ... "Medical Waste Management Market - U.S. Industry Analysis, Size, Share, ... management market in the U.S. was valued at US$ 5.89 ... CAGR of 3.4% from 2015 to 2023 to reach US$ ... analysis of current and emerging needle free drug delivery devices ...
(Date:5/25/2016)... May 25,2016 FDA 510(k) ... Cellvizio platform for urological and surgical applications ... inventor of Cellvizio®, the multidisciplinary confocal laser endomicroscopy ... in the US with the 12 th ... Administration (FDA). This new FDA clearance covers Confocal ...
Breaking Medicine Technology: