Navigation Links
OHSU Cancer Instutute researchers find abnormalities in gene for melanoma
Date:5/29/2008

PORTLAND, Ore. New research from the Oregon Health & Science University Cancer Institute about mutations in melanoma may bring a wellspring of hope to many patients.

Researchers have discovered that there are several different kinds of DNA abnormalities that can occur in a gene called the KIT gene. These abnormalities are associated with different kinds of acral and mucosal melanomas, which are less common, but highly malignant forms of skin cancer. Acral melanomas are found on the palms of hands, the soles of feet and under nails. Mucosal melanomas are found in the mucous membranes of some organs of the body.

If scientists can figure out the mutation, effective treatments can follow, explained Michael Heinrich, M.D., co-principal investigator, OHSU Cancer Institute member and head of the Hematology and Medical Oncology Section at the Portland Veterans Affairs Medical Center. The co-investigator is Christopher Corless, M.D., Ph.D., OHSU Cancer Institute member.

The research will be presented Sunday, June 1, at 5 p.m. during the annual American Society of Clinical Oncology in Chicago.

This study builds on recent research about the first instance in which a womans metastatic melanoma was driven into remission by the targeted therapy drug, Gleevec, which was developed at the OHSU Cancer Institute. Previously there had been few effective treatments for melanoma patients with metastatic disease. But not all melanomas respond so successfully to Gleevec.

In the current study, Heinrich and colleagues studied 129 samples gathered from people with different types of melanoma and found that there is a high rate of mutations in these cancers.

This means that if we can find the melanoma early, it can be screened to see what type of mutations are present, and eventually you can get the right medication or treatment, Heinrich said.

Heinrich explained that it is similar to testing of breast cancer tumors to decide if patients should receive s
'/>"/>

Contact: Christine Decker
deckerch@ohsu.edu
503-494-8231
Oregon Health & Science University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Enzyme may hold key to improved targeting of cancer-fighting drugs
2. Diabetes doubles liver cancer risk for patients with advanced hepatitis C
3. OHSU Cancer Institute researchers find many stomach cancer patients are not gertting best therapy
4. Certain Tests in ERs Raise Cancer Risk for Some
5. Combination of 2 novel anti-cancer agents may help fight CML resistant to current therapy
6. Initiative Links Celebrities to Cancer Research
7. USC researchers identify genetic markers that predict efficacy of novel cancer drug
8. Breast-Specific Gamma Imaging (BSGI) Found to Be Highly Sensitive for Early Stage Breast Cancer
9. Susan G. Komen for the Cure(R) Celebrity Ambassadors to Convene in Nations Capital to Help Race for the Cure, End Breast Cancer Forever
10. American Cancer Society, Patient Advocate Foundation Announce Free, Personalized Assistance for Cancer Patients
11. USC study finds sex, age and ethnicity assciated with colorectal cancer survival
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... New high priced hepatitis C drugs will ... projected $2.9 to $5.8 billion next year, according to ... today by the Pharmaceutical Care Management Association (PCMA). Milliman ... as much as 8.6 percent in 2015 as a ... Olysio. , The study finds that the majority of ...
(Date:7/29/2014)... Alto, CA (PRWEB) July 29, 2014 ... and well-being in older adults. Once again, the non-profit agency ... Celebration, a free event for seniors. , This event gives ... active and maintain better health. There will be a variety ... and dancing, wellness vendors, tech demonstrations and artists. In addition, ...
(Date:7/29/2014)... kidney transplants receive steady follow-up care, the living ... make follow-up care more accessible, UC San Francisco ... to launch the first program in the country ... to living kidney donors. , UCSF will provide ... than 4,500 Walgreens pharmacies and Healthcare Clinic at ...
(Date:7/29/2014)... Bret Busacker , a partner in ... appointed to the Board of Directors for the American ... experienced business attorney with a focus on employee benefits ... wide spectrum of topics regarding equity and incentive compensation, ... His clients include public and private businesses, governmental entities, ...
(Date:7/29/2014)... Georgia (PRWEB) July 29, 2014 Just ... expanding offices to 4 new states, the exciting FX ... Special FX and one time farmboy from Arkansas, is ... of bringing innovative event technologies to the masses. ... the event packed island of Jamaica. This new ...
Breaking Medicine News(10 mins):Health News:New Milliman Study: Hepatitis C Drugs Could Increase Medicare Part D Spending by $2.9 to $5.8 Billion in 2015 2Health News:Avenidas Hosts Third Annual Successful Aging Celebration 2Health News:Caring for donors 2Health News:Caring for donors 3Health News:Holland & Hart Partner Brett Busacker Appointed to Board of Directors for American Red Cross of Greater Idaho 2Health News:Atlanta Special FX Rapidly Expanding Just Opens First International Corporate Office in Jamaica 2
... ... seek pain-relief that doesn,t come in traditional drug-form. With the launch of Oram Plus, developer ... ... has done it again with the development of his new gum disease treatment, Oram Plus., ...
... , ... ... ... ...
... Phoenix magazine, the ... 44-year history in April, both in terms of page count and magazine advertising sales revenue. ... ... economic climate where newspapers and magazines are struggling, Phoenix magazine is setting an ...
... , ... ... ... ...
... An asthma program specifically tailored to teens could help ... fatal complications, Medical College of Georgia researchers say. Black ... times greater than their white counterparts, and Dr. Dennis Ownby, ... and Immunology, believes asthma rates are as bad in rural ...
... ... recorded over a unique Celtic themed musical soundscape. , ... (PRWEB) March 9, 2010 -- Welsh Tree LLC ... ,Celtic Pathways by Jason Evans, in time for Saint Patrick,s Day, Wednesday March 17th. ...
Cached Medicine News:Health News:Oram Plus Set to Take the Pain out of Gum Disease and Cavities, Naturally 2Health News:The Pediatric Dengue Vaccine Initiative Introduces www.DengueWatch.org - a News hub for Tracking Dengue Fever Epidemics Worldwide 2Health News:The Pediatric Dengue Vaccine Initiative Introduces www.DengueWatch.org - a News hub for Tracking Dengue Fever Epidemics Worldwide 3Health News:The Pediatric Dengue Vaccine Initiative Introduces www.DengueWatch.org - a News hub for Tracking Dengue Fever Epidemics Worldwide 4Health News:The Pediatric Dengue Vaccine Initiative Introduces www.DengueWatch.org - a News hub for Tracking Dengue Fever Epidemics Worldwide 5Health News:The Pediatric Dengue Vaccine Initiative Introduces www.DengueWatch.org - a News hub for Tracking Dengue Fever Epidemics Worldwide 6Health News:Phoenix Magazine Sets Magazine Advertising Sales Record With Best Doctors Issue 2Health News:Soft? Firm? When Choosing a Mattress, One Firmness Does Not Fit All 2Health News:Soft? Firm? When Choosing a Mattress, One Firmness Does Not Fit All 3Health News:Soft? Firm? When Choosing a Mattress, One Firmness Does Not Fit All 4Health News:Program could help teens control asthma 2Health News:Welsh Tree LLC Proudly Presents the Release of the Celtic Pathways CD by Jason Evans, in Time for Saint Patrick's Day 2Health News:Welsh Tree LLC Proudly Presents the Release of the Celtic Pathways CD by Jason Evans, in Time for Saint Patrick's Day 3
(Date:7/29/2014)... 29, 2014 Research and Markets ... Devices Market 2014-2018" report to their offering. ... respiratory device is a medical device used to provide ... in breathing and cannot achieve adequate oxygen levels to ... fibrosis, asthma, COPD, and ARDS require the need of ...
(Date:7/29/2014)... MOUNTAIN VIEW, Calif. , July 29, 2014 ... personal emergency response systems (PERS) market, Frost & ... Frost & Sullivan Award for Price Performance Value ... mobile usage directly captures expectations for tech progression ... of US consumers for these solutions. ...
(Date:7/29/2014)... CITY , July 29, 2014  The ... Grand American Hotel in Salt Lake City ... representing some of most respected healthcare organizations in the ... Catalyst , is an industry conference devoted to providing ... analytics,  an essential element of both accountable care initiatives ...
Breaking Medicine Technology:Global Respiratory Devices Market 2014-2018 2Frost & Sullivan Applauds MobileHelp for its Targeted Supplies for the PERS Market 2Frost & Sullivan Applauds MobileHelp for its Targeted Supplies for the PERS Market 3Health Catalyst Adds Keynote Speakers, New Sessions, and Expands Attendee Limit for Healthcare Analytics Summit 2014 2Health Catalyst Adds Keynote Speakers, New Sessions, and Expands Attendee Limit for Healthcare Analytics Summit 2014 3Health Catalyst Adds Keynote Speakers, New Sessions, and Expands Attendee Limit for Healthcare Analytics Summit 2014 4Health Catalyst Adds Keynote Speakers, New Sessions, and Expands Attendee Limit for Healthcare Analytics Summit 2014 5
... July 12 For two weeks beginning July 12 , ecoSTORE USA ... $1 off in-store coupon at 200 select Duane Reade drug stores in ... about why making No Nasty Ch e mic ... important. , , , ...
... GUANGZHOU, China , July 9 /PRNewswire-Asia/ -- ... "the Company"), a leading,manufacturer, developer and distributor of Western ... that its board of directors authorized a stock repurchase ... stock up to a value,of $2.0 million . ...
Cached Medicine Technology:Ecovisors to Advise Duane Reade Shoppers 2Ecovisors to Advise Duane Reade Shoppers 3China Medicine Announces Stock Repurchase Plan 2China Medicine Announces Stock Repurchase Plan 3
Shandon Paraffin Block Cartons...
... A histological embedment block ... This file system incorporates ... embedment block protection, simplified ... error and facilitation of ...
The Modular Storage Drawers provide permanent storage and identification of up to 165 embedding rings or 250 cassettes per drawer....
... The first instrumentation ... efficiently manage the ... Proven technology automatically ... collates cassettes sequentially. ...
Medicine Products: