Navigation Links
OHSU Cancer Institute researchers study breathing during radiation

PORTLAND, Ore. Oregon Health & Science University researchers have determined exactly how much breathing affects prostate movement during radiation treatment.

The results of this research are being presented from 5 p.m. to 6:30 p.m. today at the 50th annual American Society for Therapeutic Radiology and Oncology in Boston.

"Many people think that the prostate is a static organ, meaning that it doesn't move in relation to the bony pelvis, but that is not the case. The prostate is a moving organ, and we know it moves because of many factors including how full other organs are, such as the bladder," said Tasha McDonald, M.D., Radiological Society of North America research resident grant recipient, OHSU Department of Radiation Medicine.

Although previous studies have demonstrated that the prostate moves during the breathing cycle, McDonald used the new image-guided Calypso Medical System because it offers "real time" tracking. It works by using tiny beacons, inserted into the prostate, that report the exact location and the motion patterns inside the body over time.

"Our research demonstrates that the prostate moves during the breathing cycle, mostly up and down, as much as 2 millimeters. We were able to determine this motion by evaluating the Calypso tracings of patients," McDonald said. The Calypso results were also verified by other radiation technology.

"This is important information because in low-risk prostate patients, we treat the prostate (and seminal vesicles) with a small margin, 5 to 7 millimeters to account for prostate motion and set-up error. By knowing all the factors that contribute to prostate motion, we will be able to determine appropriate margins. If the margins are too large, there can be more normal tissue toxicity and if too small we could miss the prostate," McDonald said.

Greater accuracy allows the delivery of higher-dose radiation, leaving healthy cells alone. This process simultaneously reduces side effects, specifically rectal and bladder toxicities, and erectile dysfunction, as well as offering patients a better chance for a cure.

The presentation is titled, "Quantifying Respiratory-Induced Prostate Motion Using Real Time Tracking Technology."

Radiation therapy is used to treat approximately 1 million cancer patients in the United States each year. It is one of the most effective cancer therapies. Each year, 218,000 men are diagnosed with prostate cancer, according to the American Cancer Society. In prostate cancer treatment the most common side effects arise when the radiation beam misses the prostate but irradiates adjacent healthy organs, causing complications like impotence, urinary incontinence and rectal bleeding. Therefore, doctors must guard against damaging healthy tissues that surround the tumor caused by misalignment and unpredictable tumor motion.


Contact: Christine Decker
Oregon Health & Science University

Related medicine news :

1. Open cancer surgery set to become a thing of the past
2. Ovarian and Endometrial Cancer Patients Experience Improved Outcomes When Treated First by a Gynecologic Oncologist
3. Medicare HMO costs may prevent cancer patient clinical trial participation
4. Hormone Therapy Not Best for Older Prostate Cancer Patients
5. Model highlights benefits and risks of cervical cancer screening methods
6. Family History Key Player in Brain Cancer Risk
7. Nonprofit Charity for Women and Brookstone Dash to Fund Breast Cancer Support
8. Radiosurgery Proves Viable for Some Pancreatic Cancers
9. Pitt research indicates new virus is culprit, not bystander, in deadly skin cancer
10. Risk of colorectal cancer extremely low 5 years after a normal colonoscopy screening
11. Whole brain radiation increases risk of learning and memory problems in cancer patients
Post Your Comments:
(Date:11/30/2015)... ... , ... According to an article published November 13th by People ... to show her Instagram followers that the praise that they were bestowing on her ... she didn’t “want to mislead any mommy's who just had babies and are stressing,” ...
(Date:11/30/2015)... ... ... Cycling, running, and walking are regular Sunday activities for many South Floridians, ... 2016. , That’s when the 7th annual ANF Group Tour de Broward will ... families at Joe DiMaggio Children’s Hospital. , The community fundraiser, sponsored by ...
(Date:11/30/2015)... ... November 30, 2015 , ... ... component of bacteria could be effective in fighting methicillin-resistant Staphylococcus aureus (MRSA), one ... , Their study showed that small molecule analogs that target the functions of ...
(Date:11/30/2015)... ... November 30, 2015 , ... Using a combination of two blood sugar ... and adults, according to a new study by researchers at the School of Public ... and Adults: Using Combinations of Blood Glucose Tests ,” published in Frontiers in Public ...
(Date:11/30/2015)... Pittsburgh, PA (PRWEB) , ... November 30, 2015 ... ... according to a new study by UPMC and KingMed Diagnostics ... UPMC over three years found that consultation with UPMC pathologists resulted in significantly ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... 2015 Booth #4303 – The Imaging Components business ... a broader array of products in a new booth (#4303) ... North America in Chicago ... feature X-ray components "At the Heart of Imaging." Products will ... from Varian,s Claymount brand, and computer-aided diagnostic software from MeVis ...
(Date:11/30/2015)... NAMUR , Belgium , Nov. 30, ... life sciences company focused on developing blood-based diagnostic tests for ... announced the Company will present at the LD Micro Conference, ... Los Angeles, CA. Attending from VolitionRx will ... and Scott Powell , Vice President of Investor Relations. ...
(Date:11/30/2015)... and REHOVOT, Israel , ... specialty pharmaceutical company focused on acquiring and developing innovative ... announced the appointment of Keith A. Katkin ... Gregory J. Flesher , chief executive officer for ... building successful organizations.  As chairman, he will be able ...
Breaking Medicine Technology: