Navigation Links
OHSU Cancer Institute researcher: radiation, immunotherapy gives greater effectiveness
Date:9/25/2008

PORTLAND, Ore. Oregon Health & Science University Cancer Institute researchers have found the right formula of radiation and immunotherapy for fighting lung cancer tumors in mice, which they hope will translate to better treatment in human lung cancers.

The study was presented today at the 50th annual American Society for Therapeutic Radiology and Oncology conference in Boston.

Principal investigator Marka Crittenden, M.D., Ph.D., and colleagues designed the study in order to look at the effects of stereotactic body radiation therapy (SBRT) on the immune system. This type of radiation is delivered in three large doses over several days. The extreme precision of this technology helps to spare normal, healthy tissue, more accurately targeting the cancerous tumor.

"We studied the consequences of SBRT radiation doses in preclinical tumors and found that there were fewer of the cells that turn off the immune system and more of the good 'killer' immune cells following these radiation doses," said Crittenden, OHSU Department of Radiation Medicine, OHSU School of Medicine.

Researchers then selected a form of immunotherapy that could boost the immune response while working with the immune response generated by the SBRT. Cancer immunotherapy works to boost the body's own immune system to attack tumor cells. They found that SBRT combined with immunotherapy was much more effective at clearing the tumor than either used alone.

"We hope to translate this to patient studies and develop therapies combining the potent tumor destruction of SBRT with the patient's own immune system to further improve the efficacy of radiation therapy for cancer," Crittenden said.

The presentation is titled: "Development of a Preclinical Model to Test Adjuvant Immunotherapy in Combination With SBRT."


'/>"/>

Contact: Christine Decker
deckerch@ohsu.edu
503-494-8231
Oregon Health & Science University
Source:Eurekalert

Page: 1

Related medicine news :

1. Video: One A Day(R) and Ellen DeGeneres Team Up to Deliver a Message to Women About Breast Cancer Through The One A Day Womens Wake-Up Call Program
2. Breast Cancer Action Targets Yoplait in Think Before You Pink Campaign; Calls for Yogurt Without Artificial Hormones
3. Early Breast Cancer No More Likely to Return in Young Women
4. Chilis Grill & Bar(R) to Donate 100 Percent of All Profits on Monday, Sept. 29 to St. Jude Childrens Research Hospital as Part of Annual Create-A-Pepper to Fight Childhood Cancer Campaign
5. Cancer patients who receive neoadjuvant therapy followed by mastectomy may not need radiation
6. Age alone should not be used to determine whether to treat prostate cancer with hormones
7. Molecular imaging technology used in gastric cancer
8. Racial disparities decline for cancer in Missouri
9. OHSU Cancer Institute researchers study breathing during radiation
10. Open cancer surgery set to become a thing of the past
11. Ovarian and Endometrial Cancer Patients Experience Improved Outcomes When Treated First by a Gynecologic Oncologist
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/10/2016)... IN (PRWEB) , ... February 10, 2016 , ... ... benefits advisory organization, welcomes S.S. Nesbitt as the latest addition to its growing ... has seven other locations throughout the Southeast, from Orlando to Huntsville and in ...
(Date:2/10/2016)... ... ... Armune BioScience signed a definitive agreement with ARCpoint Labs ... the country. Launched in April of 2015, Apifiny is the only cancer specific, non-PSA ... volume exceeded 3,000 tests in 2015. Primary care physicians and urologists have utilized Apifiny ...
(Date:2/10/2016)... ... February 10, 2016 , ... For additional information contact ... , Pioneering book "Better with Age: The Ultimate Guide to Brain Training" by award-winning ... improve memory. The book’s publication date is March 16, 2016. A free review ...
(Date:2/10/2016)... ... February 10, 2016 , ... Everseat has joined the award-winning ... to physicians. The integration will enable Allscripts users to post open appointments to ... mobile app. , The partnership gives Everseat substantial added power to help Allscripts ...
(Date:2/10/2016)... ... ... Workrite Ergonomics this week announced the launch of the Conform Monitor Arm Series, ... was to develop a product from the ground up that would provide the most ... Hulsey, Product Manager for Workrite Ergonomics. “The Conform series features a wide variety ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... BASEL, Switzerland and SAN DIEGO ... Houston , Inc., a global leader in viral gene ... gene therapy treatments for congestive heart failure and other ... to develop a scalable manufacturing process and produce cGMP-grade ... clinical trials. --> ...
(Date:2/10/2016)... Immune Pharmaceuticals Inc. (NASDAQ: IMNP ), ... has filed a patent application directed to the treatment ... --> --> The new invention ... (histamine dihydrochloride) in combination with immune checkpoint inhibitors. The ... of Ceplene and IL-2 therapy in patients with Acute ...
(Date:2/10/2016)... ANGELES , Feb. 10, 2016  Oxis International ... cancer drug, OXS-1550, was described as a "clinical trial ... the drug went into complete cancer remission. ... University of Minnesota Masonic Cancer Center. --> ... University of Minnesota Masonic Cancer Center. --> ...
Breaking Medicine Technology: